Non-Alcoholic Steatohepatitis (NASH)

Infectious Diseases
8
Pipeline Programs
7
Companies
11
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
0
4
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Peptide
1100%
+ 7 programs with unclassified modality

Competitive Landscape

7 companies ranked by most advanced pipeline stage

GS
Gilead SciencesFOSTER CITY, CA
2 programs
2
SELPhase 2
SELPhase 25 trials
Active Trials
NCT03278990Terminated26Est. Dec 2020
NCT03487900Unknown320Est. Dec 2023
NCT02466516Completed72Est. Oct 2016
+2 more trials
Inventiva
InventivaDAIX, France
1 program
1
IVA337Phase 21 trial
Active Trials
NCT03008070CompletedEst. Mar 2020
Boehringer Ingelheim
Boehringer IngelheimINGELHEIM, Germany
1 program
1
SurvodutidePhase 2Peptide1 trial
Active Trials
NCT04771273Completed295Est. Dec 2023
Eccogene
EccogeneChina - Shanghai
1 program
1
ECC4703Phase 11 trial
Active Trials
NCT05552274CompletedEst. Oct 2023
Galectin Therapeutics
1 program
1
GR-MD-02Phase 11 trial
Active Trials
NCT01899859CompletedEst. Feb 2015
Corcept Therapeutics
Corcept TherapeuticsCA - Redwood City
1 program
1
MiricorilantPhase 11 trial
Active Trials
NCT05553470Completed19Est. Sep 2024
Novo Nordisk
Novo NordiskBAGSVAERD DENMARK, Denmark
1 program
1
NNC0194-0499Phase 11 trial
Active Trials
NCT05727644Completed42Est. Nov 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Boehringer IngelheimSurvodutide
InventivaIVA337
Gilead SciencesSEL
Novo NordiskNNC0194-0499
EccogeneECC4703
Corcept TherapeuticsMiricorilant
Galectin TherapeuticsGR-MD-02
Gilead SciencesSEL
Gilead SciencesSEL
Gilead SciencesSEL
Gilead SciencesSEL

Clinical Trials (11)

Total enrollment: 1,404 patients across 11 trials

A Study to Test Safety and Efficacy of Survodutide (BI456906) in Adults With Non-alcoholic Steatohepatitis (NASH) and Fibrosis (F1-F3)

Start: Apr 2021Est. completion: Dec 2023295 patients
Phase 2Completed

Phase 2b Study in NASH to Assess IVA337

Start: Feb 2017Est. completion: Mar 2020
Phase 2Completed

Safety, Tolerability, and Efficacy of GS-4997 Alone or in Combination With Simtuzumab (SIM) in Adults With Nonalcoholic Steatohepatitis (NASH) and Fibrosis Stages F2-F3

Start: Jun 2015Est. completion: Oct 201672 patients
Phase 2Completed

A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function

Start: Feb 2023Est. completion: Nov 202342 patients
Phase 1Completed

FTIH of ECC4703 in Healthy Volunteers

Start: Aug 2022Est. completion: Oct 2023
Phase 1Completed

Study to Evaluate the Effects of Hepatic Impairment on the Pharmacokinetics of Miricorilant

Start: Mar 2022Est. completion: Sep 202419 patients
Phase 1Completed

Phase 1 Study to Evaluate Safety of GR-MD-02 in Subjects With Non-Alcoholic Steatohepatitis (NASH) and Advanced Fibrosis

Start: Jul 2013Est. completion: Feb 2015
Phase 1Completed

Dose Escalation Study of CAL-101 in Select Relapsed or Refractory Hematologic Malignancies

Start: Jun 2008Est. completion: Aug 2012192 patients
Phase 1Completed

Scalable Interventions to Increase PrEP Adherence: Value Affirmation and Future Selves

Start: Dec 2018Est. completion: Dec 202026 patients
N/ATerminated

Is the Endoscopic Remission Evaluation, Using the CREDO 1 Index / Score in CD Patients in Clinical Remission at Baseline, Predictive of Sustained Clinical Remission Using a 2-year Follow up

Start: Mar 2018Est. completion: Dec 2023320 patients
N/AUnknown

Intervention to Enhance PrEP Uptake and Adherence in a Community-Based Setting

Start: Jan 2014Est. completion: Jun 2018438 patients
N/ACompleted

Related Jobs in Infectious Diseases

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

7 companies competing in this space