HIV Disease

Infectious Diseases
2
Pipeline Programs
4
Companies
4
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
2
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

CSL Behring
CSL BehringIL - Bradley
1 program
1
alpha-1-Proteinase InhibitorPhase 2/31 trial
Active Trials
NCT01370018Completed4Est. Feb 2007
Grifols
GrifolsNEW YORK, NY
1 program
1
α1 Proteinase InhibitorPhase 2/31 trial
Active Trials
NCT01731691TerminatedEst. Jul 2014
Rational Vaccines
1 program
Blood drawN/A1 trial
Active Trials
NCT05823779UnknownEst. Apr 2025
GS
Gilead SciencesFOSTER CITY, CA
1 program
StribildN/A1 trial
Active Trials
NCT01929759Completed10Est. Oct 2015

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Grifolsα1 Proteinase Inhibitor
CSL Behringalpha-1-Proteinase Inhibitor
Rational VaccinesBlood draw
Gilead SciencesStribild

Clinical Trials (4)

Total enrollment: 14 patients across 4 trials

NCT01731691Grifolsα1 Proteinase Inhibitor

Safety and Efficacy of (α1Proteinase Inhibitor, α1PI) in HIV Disease

Start: Apr 2012Est. completion: Jul 2014
Phase 2/3Terminated
NCT01370018CSL Behringalpha-1-Proteinase Inhibitor

Therapy to Elevate CD4 Counts in HIV-1 Disease

Start: Dec 2006Est. completion: Feb 20074 patients
Phase 2/3Completed
NCT05823779Rational VaccinesBlood draw

A 48 Week Observational Study of the Frequency of Symptomatic Herpes Virus I and II in HIV Infected Subjects

Start: Apr 2022Est. completion: Apr 2025
N/AUnknown
NCT01929759Gilead SciencesStribild

Advanced Neuroimaging Evaluation of the Central Nervous System Biological Changes Associated With Efavirenz Therapy and Switch to an Elvitegravir-based Regimen

Start: Jan 2014Est. completion: Oct 201510 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

Related Indications

HIV Infections(449)COVID-19(223)Hepatitis C(191)Influenza(173)HIV(138)HIV-1-infection(115)Hepatitis C, Chronic(94)Chronic Hepatitis B(93)Chronic Hepatitis C(91)Covid19(79)