Generalized Epilepsy

Neurology
7
Pipeline Programs
2
Companies
3
Clinical Trials
4
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
1
2
4
Early DiscoveryClinical DevelopmentMarket

On Market (4)

Approved therapies currently available

UP
KEPPRAApproved
levetiracetam
UCB Pharma
oral2003
UP
KEPPRA XRApproved
levetiracetam
UCB Pharma
oral2008
U
LEVETIRACETAMApproved
levetiracetam
Unknown Company
oral2012
U
SPRITAMApproved
levetiracetam
Unknown Company
oral2015

Competitive Landscape

2 companies ranked by most advanced pipeline stage

UP
UCB PharmaBelgium - Brussels
2 programs
2
1
LEVETIRACETAMPhase 31 trial
Levetiracetam 166 mgPhase 31 trial
Active Trials
NCT00150735Completed580Est. Jul 2005
NCT00150748Completed217Est. Jul 2007
Biohaven
BiohavenNEW HAVEN, CT
1 program
1
BHV-7000Phase 2/31 trial
Active Trials
NCT06425159Active Not RecruitingEst. Jul 2027

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
UCB PharmaLEVETIRACETAM
UCB PharmaLevetiracetam 166 mg
BiohavenBHV-7000

Clinical Trials (3)

Total enrollment: 797 patients across 3 trials

NCT00150735UCB PharmaLEVETIRACETAM

Monotherapy With Levetiracetam in Newly Diagnosed Patients Suffering From Epilepsy

Start: Jun 2002Est. completion: Jul 2005580 patients
Phase 3Completed
NCT00150748UCB PharmaLevetiracetam 166 mg

Long Term Follow up Treatment With Levetiracetam in Subjects of 4 Years and Older With Generalized Epilepsy

Start: Nov 2001Est. completion: Jul 2007217 patients
Phase 3Completed
NCT06425159BiohavenBHV-7000

A Study to Determine if BHV-7000 is Effective and Safe in Adults With Idiopathic Generalized Epilepsy With Generalized Tonic-clonic Seizures

Start: Jun 2024Est. completion: Jul 2027
Phase 2/3Active Not Recruiting

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
2 companies competing in this space

Related Indications

Multiple Sclerosis(274)Schizophrenia(255)Epilepsy(242)Parkinson Disease(171)Alzheimer's Disease(165)Parkinson's Disease(160)Alzheimer Disease(117)Stroke(102)Relapsing-Remitting Multiple Sclerosis(83)Depression(82)