Corneal Edema

Ophthalmology
7
Pipeline Programs
2
Companies
7
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
1
1
0
1
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Aurion Biotech
Aurion BiotechWA - Seattle
4 programs
1
1
1
1
Combination Product: AURN001 + Y-27632Phase 31 trial
Cryopreserved AURN001Phase 21 trial
AURN001Phase 1/21 trial
HCEC-1Phase 11 trial
Active Trials
NCT05309135Completed22Est. Mar 2023
NCT06041256Completed97Est. Apr 2025
NCT06630169Active Not Recruiting25Est. Oct 2025
+1 more trials
Emmecell
EmmecellCA - Menlo Park
3 programs
3
EO1404Phase 11 trial
EO2002Phase 11 trial
EO2002Phase 11 trial
Active Trials
NCT04191629Unknown35Est. Feb 2021
NCT05636579Recruiting12Est. Dec 2025
NCT04894110Completed42Est. Oct 2024

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Aurion BiotechCombination Product: AURN001 + Y-27632
Aurion BiotechCryopreserved AURN001
Aurion BiotechAURN001
EmmecellEO2002
Aurion BiotechHCEC-1
EmmecellEO2002
EmmecellEO1404

Clinical Trials (7)

Total enrollment: 353 patients across 7 trials

NCT07368959Aurion BiotechCombination Product: AURN001 + Y-27632

AURN001 Efficacy in Participants With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Start: May 2026Est. completion: Jan 2028120 patients
Phase 3Not Yet Recruiting
NCT06630169Aurion BiotechCryopreserved AURN001

Study of Cryopreserved AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction

Start: Sep 2024Est. completion: Oct 202525 patients
Phase 2Active Not Recruiting

A Phase 1/2 Study of AURN001 in Subjects With Corneal Edema Secondary to Corneal Endothelial Dysfunction (ABA-1)

Start: Oct 2023Est. completion: Apr 202597 patients
Phase 1/2Completed

Study to Assess Safety and Tolerability of Multiple Doses of EO2002

Start: Nov 2022Est. completion: Dec 202512 patients
Phase 1Recruiting

A Safety and Efficacy Study of Corneal Injection for Endothelial Dysfunction Using Human Corneal Endothelial Cell Therapy in Subjects With Corneal Edema Secondary to Endothelial Dysfunction

Start: Mar 2022Est. completion: Mar 202322 patients
Phase 1Completed

Study of Safety and Tolerability of EO2002 in the Treatment of Corneal Edema

Start: Jun 2021Est. completion: Oct 202442 patients
Phase 1Completed

Phase 1 Study to Evaluate the Safety and Tolerability of EO1404 in the Treatment of Corneal Edema

Start: May 2016Est. completion: Feb 202135 patients
Phase 1Unknown

Related Jobs in Ophthalmology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 353 patients
2 companies competing in this space