Community-acquired Pneumonia

Infectious Diseases
4
Pipeline Programs
3
Companies
4
Clinical Trials
1 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
2
1
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
2100%
+ 2 programs with unclassified modality

On Market (1)

Approved therapies currently available

Paratek Pharmaceuticals
NUZYRAApproved
omadacycline
Paratek Pharmaceuticals
Tetracycline-class Antibacterial [EPC]intravenous2018

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Paratek Pharmaceuticals
2 programs
1
1
1
OmadacyclinePhase 3Small Molecule1 trial
OmadacyclinePhase 1Small Molecule1 trial
Active Trials
NCT04160260Completed18Est. Apr 2020
NCT04779242Completed670Est. Mar 2024
Biotest Pharmaceuticals
Biotest PharmaceuticalsGermany - Dreieich
1 program
1
TrimodulinPhase 31 trial
Active Trials
NCT05722938RecruitingEst. Jul 2028
Pfizer
PfizerNEW YORK, NY
1 program
Urinary antigen detection assayN/A1 trial
Active Trials
NCT03696303Completed959Est. Mar 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
Biotest PharmaceuticalsTrimodulin
Paratek PharmaceuticalsOmadacycline
Paratek PharmaceuticalsOmadacycline
PfizerUrinary antigen detection assay

Clinical Trials (4)

Total enrollment: 1,647 patients across 4 trials

Efficacy and Safety of Trimodulin (BT588) in Subjects With Severe Community-acquired Pneumonia (sCAP)

Start: Sep 2023Est. completion: Jul 2028
Phase 3Recruiting

Omadacycline vs. Moxifloxacin for the Treatment of Community-Acquired Bacterial Pneumonia

Start: Feb 2021Est. completion: Mar 2024670 patients
Phase 3Completed

Study to Evaluate the PK of PO Omadacycline in Adults With Community-Acquired Bacterial Pneumonia

Start: Nov 2019Est. completion: Apr 202018 patients
Phase 1Completed
NCT03696303PfizerUrinary antigen detection assay

Determination of the Utility of Pfizer's Pneumococcal Urine Antigen Test in Children 5 Years of Age or Younger With Community Acquired Pneumonia in Guatemala

Start: Mar 2019Est. completion: Mar 2022959 patients
N/ACompleted

Related Jobs in Infectious Diseases

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
1 actively recruiting trials targeting 1,647 patients
3 companies competing in this space