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Chronic Inflammatory Demyelinating Polyneuropathy

Neurology
4
Pipeline Programs
10
Companies
16
Clinical Trials
6 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
0
0
3
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 22 programs with unclassified modality

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.6yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

Competitive Landscape

9 companies ranked by most advanced pipeline stage

CSL Seqirus
CSL SeqirusUK - Maidenhead
6 programs
2
10% liquid formulation of human immunoglobulinPhase 3
IgPro20Phase 3
HOME LINKN/A
HizentraN/A
Immune Globulin SubcutaneousN/A
+1 more programs
Nihon Pharmaceutical
1 program
1
NPB-01Phase 31 trial
Active Trials
NCT01824251Completed49Est. Sep 2015
Kite Pharma
Kite PharmaCA - El Segundo
1 program
1
KITE-363Phase 11 trial
Active Trials
NCT07304154Recruiting52Est. Jun 2029
CSL Behring
CSL BehringIL - Bradley
6 programs
HOME LINKN/A1 trial
HizentraN/A1 trial
Immune Globulin SubcutaneousN/A1 trial
Intravenous ImmunoglobulinN/A1 trial
10% liquid formulation of human immunoglobulinPHASE_31 trial
+1 more programs
Active Trials
NCT03779828Terminated11Est. Jun 2019
NCT04672733Recruiting100Est. Dec 2027
NCT02465359Completed15Est. May 2021
+3 more trials
Immunovant
ImmunovantDURHAM, NC
3 programs
BatoclimabPHASE_2Monoclonal Antibody1 trial
Batoclimab 680 milligramsPHASE_21 trial
IMVT-1402PHASE_21 trial
Active Trials
NCT07188844Enrolling By Invitation108Est. Nov 2028
NCT05581199Active Not Recruiting277Est. Jan 2027
NCT07032662Recruiting162Est. May 2030
argenx
argenxBelgium - Zwijnaarde
3 programs
Empasiprubart IVPHASE_31 trial
empasiprubartPHASE_31 trial
Efgartigimod PH20 SCPHASE_41 trial
Active Trials
NCT07091630Recruiting160Est. Jan 2031
NCT06920004Recruiting218Est. Sep 2030
NCT06637072Completed23Est. Feb 2026
Alnylam Pharmaceuticals
1 program
CIDP treatment patterns and outcomesN/A
Octapharma
OctapharmaAustria - Vienna
1 program
ImmunoglobulinsN/A1 trial
Active Trials
NCT02111590Completed36Est. Jul 2015
Dianthus Therapeutics
1 program
DNTH103PHASE_31 trial
Active Trials
NCT06858579Recruiting256Est. Dec 2030

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
argenxEfgartigimod PH20 SC
argenxEmpasiprubart IV
argenxempasiprubart
Dianthus TherapeuticsDNTH103
Nihon PharmaceuticalNPB-01
CSL BehringIgPro20
CSL Behring10% liquid formulation of human immunoglobulin
ImmunovantBatoclimab
ImmunovantIMVT-1402
ImmunovantBatoclimab 680 milligrams
Kite PharmaKITE-363
CSL BehringHizentra
CSL BehringHOME LINK
CSL BehringIntravenous Immunoglobulin
CSL BehringImmune Globulin Subcutaneous

Showing 15 of 16 trials with date data

Clinical Trials (16)

Total enrollment: 1,736 patients across 16 trials

NCT06637072argenxEfgartigimod PH20 SC

A Study to Assess Adults With CIDP Transitioning From IVIg to Efgartigimod PH20 SC

Start: Dec 2024Est. completion: Feb 202623 patients
Phase 4Completed
NCT07091630argenxEmpasiprubart IV

A Study to Assess the Efficacy and Safety of Empasiprubart in Adults With CIDP

Start: Sep 2025Est. completion: Jan 2031160 patients
Phase 3Recruiting
NCT06920004argenxempasiprubart

A Study to Assess Efficacy and Safety of Empasiprubart Versus IVIg in Adults With CIDP

Start: Aug 2025Est. completion: Sep 2030218 patients
Phase 3Recruiting

A Study to Evaluate the Efficacy and Safety of DNTH103 in Adults With Chronic Inflammatory Demyelinating Polyneuropathy (CAPTIVATE)

Start: Feb 2025Est. completion: Dec 2030256 patients
Phase 3Recruiting

Phase III Clinical Trial of NPB-01maintenance Therapy in Patients With Chronic Inflammatory Demyelinating Polyneuropathy.

Start: Apr 2013Est. completion: Sep 201549 patients
Phase 3Completed

Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) and Treatment With Subcutaneous Immunoglobulin (IgPro20)

Start: Mar 2012Est. completion: Sep 2016208 patients
Phase 3Completed
NCT01184846CSL Behring10% liquid formulation of human immunoglobulin

Study of Efficacy and Safety of Privigen in Subjects With Chronic Inflammatory Demyelinating Polyneuropathy

Start: Nov 2010Est. completion: Nov 201131 patients
Phase 3Completed

An Open-Label Extension Study of Batoclimab in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Start: Aug 2025Est. completion: Nov 2028108 patients
Phase 2Enrolling By Invitation

IMVT-1402 in Adult Participants With Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Start: Mar 2025Est. completion: May 2030162 patients
Phase 2Recruiting
NCT05581199ImmunovantBatoclimab 680 milligrams

To Assess Efficacy and Safety of Batoclimab in Adult Participants With Active CIDP

Start: Dec 2022Est. completion: Jan 2027277 patients
Phase 2Active Not Recruiting

A Study Evaluating the Safety and Efficacy of KITE-363 in Relapsed/Refractory Autoimmune Neurologic Diseases

Start: Apr 2026Est. completion: Jun 202952 patients
Phase 1Recruiting

Hizentra® in Inflammatory Neuropathies - pHeNIx Study

Start: Jun 2022Est. completion: Dec 2027100 patients
N/ARecruiting

Evaluating the Effectiveness of Telemonitoring System in the Management of Patients With CIDP

Start: Nov 2017Est. completion: Jun 201911 patients
N/ATerminated
NCT02414490CSL BehringIntravenous Immunoglobulin

IVIg Treatment-Related Fluctuations in CIDP Patients Using Daily Grip Strength Measurements

Start: Mar 2015Est. completion: May 202030 patients
N/ACompleted
NCT02465359CSL BehringImmune Globulin Subcutaneous

Subcutaneous Immunoglobulin for Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Start: Sep 2014Est. completion: May 202115 patients
N/ACompleted
NCT02111590OctapharmaImmunoglobulins

Immunoglobulin Dosage and Administration Form in CIDP and MMN

Start: Jan 2014Est. completion: Jul 201536 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals
6 actively recruiting trials targeting 1,736 patients
10 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.