Cataracts

Ophthalmology
4
Pipeline Programs
3
Companies
50
Clinical Trials
4 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
2
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Alcon
AlconFORT WORTH, TX
17 programs
2
2
ToricPhase 41 trial
Toric IOLPhase 41 trial
DisCoViscPhase 31 trial
Nepafenac 1mg/ml eye drops, suspensionPhase 31 trial
AcrySof® IQ PanOptix™ Presbyopia-Correcting IOLN/A1 trial
+12 more programs
Active Trials
NCT02691741Completed215Est. Jul 2017
NCT01605877Completed70Est. Dec 2013
NCT01684007CompletedEst. Aug 2013
+13 more trials
J&
Johnson & JohnsonNEW BRUNSWICK, NJ
4 programs
InterventionN/A5 trials
Model C0002N/A1 trial
Model Series ZXTN/A1 trial
Test IOL Model DEN00VN/A1 trial
Active Trials
NCT06353711Recruiting180Est. Oct 2026
NCT06767319Completed79Est. Mar 2025
NCT06646289Active Not Recruiting24Est. Oct 2030
+5 more trials
Novartis
NovartisBASEL, Switzerland
1 program
Cataract Refractive SuiteN/A1 trial
Active Trials
NCT02974140Terminated39Est. Jul 2017

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
AlconToric
Johnson & JohnsonIntervention
AlconToric IOL
Johnson & JohnsonIntervention
AlconDisCoVisc
AlconNepafenac 1mg/ml eye drops, suspension
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention
Johnson & JohnsonIntervention

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 26,731 patients across 50 trials

A Long Term Post-Marketing Study on the EffIcacy and Safety of Osmotic Release Oral System (OROS) Methylphenidate on the Cognitive Functions of Attention Deficit Hyperactivity Disorder (ADHD) Participants

Start: Dec 2009Est. completion: Nov 2010194 patients
Phase 4Completed

SORT-OUT V - Randomised Clinical Comparative Study of the Nobori and the Cypher Stent.

Start: Jul 2009Est. completion: Dec 20112,504 patients
Phase 4Completed

Comparison of Corneal Aberrations and Visual Outcomes in AcrySof IQ Toric Patients Versus Limbal Relaxing Incision (LRI) Patients

Start: Jun 2009Est. completion: Oct 20090
Phase 4Withdrawn

A Pilot Trial to Evaluate the Effect of Diet and Exercise in Renal Transplant Recipients on Tacrolimus

Start: Jul 2007Est. completion: Jun 201055 patients
Phase 4Completed

Low Cylinder Toric

Start: Jun 200726 patients
Phase 4Completed

Prodrome-Based Early Intervention With Antipsychotics vs. Benzodiazepines in First-Episode Schizophrenia

Start: Nov 2001Est. completion: Jun 200671 patients
Phase 4Completed

DisCoVisc Comparative Evaluation

Start: May 2007
Phase 3Completed
NCT00405730AlconNepafenac 1mg/ml eye drops, suspension

Nepafenac 0.1% Eye Drops, Suspension Compared to Ketorolac Trometamol 0.5% Eye Drops, Solution and Placebo

Start: Nov 2005Est. completion: Jul 2006227 patients
Phase 3Completed

Efficacy of a Web-based Tailored Weight Management Program

Start: Sep 2003Est. completion: Jul 20061,848 patients
Phase 2/3Completed

A Follow-on Study for Second-Eye Treatment for Participants Previously Treated With Gene Therapy for X-Linked Retinitis Pigmentosa (XLRP)

Start: Oct 2024Est. completion: Oct 203024 patients
Phase 2Active Not Recruiting

Methylphenidate for Apathy in Veterans With Parkinson's Disease

Start: Jan 2024Est. completion: Jun 202860 patients
Phase 2Not Yet Recruiting

CAR- PRISM (PRecision Intervention Smoldering Myeloma)

Start: Apr 2023Est. completion: Jan 204020 patients
Phase 2Active Not Recruiting

Immuno-PRISM (PRecision Intervention Smoldering Myeloma)

Start: Aug 2022Est. completion: Jul 203052 patients
Phase 2Recruiting

A Study of Health-Related Quality of Life in People With Multiple Myeloma Receiving Daratumumab or Lenalidomide

Start: Aug 2020Est. completion: Aug 202695 patients
Phase 2Active Not Recruiting

A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 4

Start: Aug 2022Est. completion: Nov 202220 patients
Phase 1Completed

A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 3

Start: Jul 2021Est. completion: Sep 202112 patients
Phase 1Completed

A Study Exploring the Use of Challenge Agents in Healthy Volunteers - Intervention Specific Appendix

Start: Mar 2021Est. completion: May 202110 patients
Phase 1Completed

A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 2

Start: Oct 2020Est. completion: May 202113 patients
Phase 1Completed

A Study Validating the Use of Candin as a Challenge Agent in Healthy Participants - Intervention Specific Appendix 1

Start: Oct 2020Est. completion: May 202112 patients
Phase 1Completed

Caring Connections Youth Suicide Detection and Intervention Study

Start: Aug 2025Est. completion: Oct 2026180 patients
N/ARecruiting

Prospective, Multi-center, Non-interventional, Open Label, Randomized (Depth of Focus Testing Sequences), Clinical Study

Start: Dec 2024Est. completion: Mar 202579 patients
N/ACompleted
NCT06377514Johnson & JohnsonTest IOL Model DEN00V

Clinical Investigation of the TECNIS® Next-Generation Intraocular Lens

Start: Jun 2024Est. completion: Apr 2025245 patients
N/ACompleted

Benefits of Individual Physical Activity Intervention on Health-related Quality of Life in Participants With Chronic Lymphocytic Leukemia

Start: May 2024Est. completion: Oct 2027180 patients
N/ARecruiting

A Multicenter, Observational, Single Arm Study of the TECNIS Presbyopia-correcting Intraocular Lens

Start: Apr 2024Est. completion: Jun 2025307 patients
N/ACompleted

Toolkit for Experiential Well-beiNg in Dementia (TEND)

Start: Feb 2024Est. completion: Apr 20240
N/AWithdrawn

A Positive Psychology Based Intervention (PATH-C) for Caregivers of HSCT Survivors

Start: Jan 2024Est. completion: Jan 202780 patients
N/AActive Not Recruiting

Evaluation of Real-World Data on the Performance of the TECNIS Odyssey™ IOL

Start: Sep 2023Est. completion: Dec 202396 patients
N/ACompleted

User Acceptability Evaluation of Pseudophakic Patients Previously Implanted With the TECNIS Odyssey IOL

Start: Sep 2023Est. completion: May 202444 patients
N/ACompleted

A Study in Participants With Major Depressive Disorder (MDD) With Anhedonia and Inadequate Response to Current Antidepressant Therapy Including a Selective Serotonin Reuptake Inhibitor (SSRI) or Serotonin Norepinephrine Reuptake Inhibitor (SNRI)

Start: Apr 2023Est. completion: Mar 2026545 patients
N/AActive Not Recruiting

A Study to Investigate Acute Respiratory Virus Infections in Participants at High Risk for Severe Illness

Start: Jan 2023Est. completion: Mar 2024140 patients
N/ACompleted

PROOF-OF-CONCEPT STUDY FOR NEW INTRAOCULAR LENS, MODEL C0002

Start: Nov 2022Est. completion: May 2025106 patients
N/ACompleted

A Post-market Clinical Study to Collect Safety and Performance Data on Johnson & Johnson Surgical Vision Products

Start: Jun 2022Est. completion: May 20251,674 patients
N/ACompleted

Imagery Interventions for Auditory Vocal Hallucinations

Start: Apr 2022Est. completion: Feb 202432 patients
N/ACompleted

Evaluation of the TECNIS Symfony® Toric Intraocular Lens

Start: Nov 2021Est. completion: Apr 202482 patients
N/ACompleted

A Study of Real-Life Current Standards of Care in Participants With Relapsed and/or Refractory Multiple Myeloma

Start: Nov 2021Est. completion: Jul 2028300 patients
N/ARecruiting

Testing the Causal Effects of a Civic Engagement Intervention on Health and Wellbeing Among Youth (I-ACTED)

Start: Jun 2021Est. completion: Aug 20251,659 patients
N/ACompleted

A Registry Study of Palmoplantar Pustulosis (PPP) Treatment Patterns, Disease Burden and Treatment Outcomes in Japan

Start: Mar 2021Est. completion: Dec 2025276 patients
N/ACompleted

Project PEER: Understanding the Lung Cancer Patient ExperiEnce in the Real-World Setting

Start: Aug 2020Est. completion: Dec 20251,300 patients
N/AUnknown

Study to Estimate How Common it is to Have Genetic Variants Associated With NAFLD

Start: Aug 2020Est. completion: Oct 2022830 patients
N/ACompleted

A Fighting Chance: Pilot Study of a Group Mentoring Intervention for Assault Injured Youth

Start: Aug 2020Est. completion: Dec 202014 patients
N/ACompleted

A Physical Activity Program to Improve Quality of Life and Reduce Fatigue in Metastatic Breast Cancer

Start: Jun 2020Est. completion: Jun 2025244 patients
N/AUnknown

A Study to Describe Routine Treatment Pathways in Participants With Major Depression and Active Suicidal Ideation With Intent in Italy

Start: Jun 2020Est. completion: Nov 2021136 patients
N/ACompleted

Prognostic Implications of Physiologic Investigation After Revascularization With Stent

Start: May 2020Est. completion: Feb 20215,100 patients
N/AUnknown

A Study of Smoking Cessation Patterns in Participants Undergoing Lung Surgery

Start: May 2020Est. completion: Dec 2021290 patients
N/ACompleted

Study of the Treatment and Outcomes in Critically Ill Patients With COVID-19

Start: Apr 2020Est. completion: Jul 20235,154 patients
N/ACompleted

Promoting Dignity, Meaningfulness and Mental Well-Being

Start: Mar 2020Est. completion: Nov 202310 patients
N/ACompleted

A Study to Evaluate the Impact of Care4Today® IBD, a Smart System to Facilitate the Management of Crohn's Disease by Patients and Health Care Providers

Start: Feb 2020Est. completion: Apr 202232 patients
N/ATerminated

A nUtrition and Lifestyle Intervention in Patients With Pulmonary Arterial HypertensIon

Start: Oct 2019Est. completion: Feb 202240 patients
N/ACompleted

A Study of Real-life Current Standards of Care in Patients With Relapsed and/or Refractory Multiple Myeloma Who Received at Least 3 Prior Lines of Therapy Including Proteasome Inhibitor (PI), Immunomodulatory Drug (IMID), and Cluster of Differentiation 38 (CD38) Monoclonal Antibody Treatment

Start: Aug 2019Est. completion: Oct 2022254 patients
N/ACompleted

A Registry Study of Participants With Multiple Myeloma in Latin America

Start: May 2019Est. completion: Jun 20222,059 patients
N/ACompleted

Related Jobs in Ophthalmology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

2 late-stage (Phase 3) programs — potential near-term approvals
4 actively recruiting trials targeting 26,731 patients
3 companies competing in this space