Alzheimer Disease, Early Onset
Neurology
3
Pipeline Programs
4
Companies
4
Clinical Trials
2 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
1
0
0
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
4 companies ranked by most advanced pipeline stage
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
2027
ADvantage TherapeuticsAD04
Denali TherapeuticsDNL628
Therini BioTHN391
Cognito TherapeuticsGammaSense Stimulation System
Clinical Trials (4)
Effects of a Widely Used Vaccine Adjuvant in Subjects With Early Alzheimer's Disease Double-blind Study to Assess the Safety and Efficacy of AD04 in Patients With Early Alzheimer's Disease - ADVANCE
Start: Nov 2023Est. completion: Jul 2027
Phase 2Active Not Recruiting
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DNL628 in Participants With Early Alzheimer's Disease
Start: Jan 2026Est. completion: Feb 2027
Phase 1Recruiting
A Study to Assess THN391 in Subjects With Alzheimer's Disease
Start: Jul 2025Est. completion: Sep 2026
Phase 1Recruiting
Study of Tolerability, Safety and Efficacy of Sensory Stimulation at Multiple Dose Levels to Improve Brain Function (Etude Study)
Start: May 2018Est. completion: Mar 2022
N/AUnknown
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 actively recruiting trials
4 companies competing in this space