Denali Therapeutics
Focus: Denali Therapeutics is a 5,000+ employee biotech company headquartered in South San Francisco specializing in neurodegenerative disease therapies with proprietary blood-brain barrier crossing antibody technology.
Profile data last refreshed 14h ago · AI intelligence enriched 2mo ago
Employees
5000+
Open Jobs
8+2 this month
Stable — net +2 jobs in 30d
5 added, 3 removed. Backfill posture.
Should You Work at Denali Therapeutics?
AI assessmentStrong science and scale appeal undermined by recent clinical failure, cost restructuring, and early-stage pipeline concentration; suitable for risk-tolerant scientists but flag execution concerns in interviews.
Why Work Here
- Deep focus on high-unmet-need neurology with 17 active clinical programs spanning Parkinson's, Alzheimer's, ALS, and rare lysosomal storage disorders
Data completeness
4/9 — Basic
Company HealthSolid
Pipeline
Mid-stage
1 Phase 3+
LOE Risk
Protected
No near-term cliffs
Hiring
Slowing
Jobs decreasing
Automated analysis based on publicly available data (FDA, SEC, ClinicalTrials.gov). May be incomplete or delayed. This score does not reflect insider knowledge and should not be used as the sole basis for investment or employment decisions.
Pipeline & Clinical Trials
No intervention
Mucopolysaccharidosis III-AClinical Trials (1)
NCT05523206A Natural History Study of Biomarkers and Clinical Outcomes in Mucopolysaccharidosis Type IIIA (MPS IIIA; Sanfilippo Syndrome)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.