Acute Stroke
Neurology
3
Pipeline Programs
4
Companies
4
Clinical Trials
1 recruiting
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
2
1
0
0
Early DiscoveryClinical DevelopmentMarket
Competitive Landscape
4 companies ranked by most advanced pipeline stage
DiaMedica TherapeuticsMINNEAPOLIS, MN
1 program1
Recombinant human tissue kallikreinPhase 2/31 trial
Active Trials
DS
Daiichi SankyoChina - Shanghai
1 programIMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke CareN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
DiaMedica TherapeuticsRecombinant human tissue kallikrein
PharmazzNormal Saline along with standard treatment
GenentechIV rt-PA
Daiichi SankyoIMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care
Clinical Trials (4)
Total enrollment: 21,774 patients across 4 trials
Treatment of Acute Ischemic Stroke (ReMEDy2 Trial)
Start: Nov 2021Est. completion: Dec 2026
Phase 2/3Recruiting
PMZ-1620 (Sovateltide) in Acute Ischemic Stroke Patients
Start: Jan 2018Est. completion: Jun 201940 patients
Phase 2Completed
A Study of Intravenous Thrombolysis With Alteplase in MRI-Selected Patients
Start: Jan 2011Est. completion: May 201688 patients
Phase 2Completed
NCT04242784Daiichi SankyoIMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care
IMPROVE Stroke Care- Developing and Optimizing Regional Systems of Stroke Care
Start: Jan 2019Est. completion: Apr 202121,646 patients
N/ACompleted
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Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
1 actively recruiting trials targeting 21,774 patients
4 companies competing in this space