In Vitro Fertilization
6
Pipeline Programs
3
Companies
4
Clinical Trials
3
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
2
4
Early DiscoveryClinical DevelopmentMarket
On Market (3)
Approved therapies currently available
U
PROGESTASERTApproved
progesterone
Unknown Companyintrauterine1976
U
PROGESTERONEApproved
progesterone
Unknown CompanyProgesterone [EPC]oral2017
U
PROMETRIUMApproved
progesterone
Unknown Companyoral1998
Competitive Landscape
3 companies ranked by most advanced pipeline stage
M&
IBSA Institut BiochimiqueSwitzerland - Lugano-Pazzallo
2 programs2
ProgesteronePhase 31 trial
ProgesteronePhase 31 trial
Active Trials
City TherapeuticsMA - Cambridge
1 programEstrogen Levels and Postoperative Recovery in IVF PatientsN/A1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
Merck & Co.Gonal -f® [r-hFSH]
IBSA Institut BiochimiqueProgesterone
IBSA Institut BiochimiqueProgesterone
City TherapeuticsEstrogen Levels and Postoperative Recovery in IVF Patients
Clinical Trials (4)
EXpression PRofile Endometrium Samples Study
Start: Aug 2008Est. completion: Aug 2010
Phase 4Terminated
Subcutaneous Progesterone Versus Vaginal Progesterone Gel for Luteal Phase Support in Patients Undergoing In-Vitro Fertilization (IVF)
Start: Jan 2009Est. completion: May 2011
Phase 3Completed
Subcutaneous Progesterone Versus Vaginal Progesterone Tablets for Luteal Phase Support in In Vitro Fertilization (IVF)
Start: Dec 2008Est. completion: Feb 2012
Phase 3Completed
Estrogen Levels and Postoperative Recovery in IVF Patients
Start: Apr 2025Est. completion: Dec 2025
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
2 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space