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Urethral Stricture

1
Pipeline Programs
3
Companies
4
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Laborie
LaborieNH - Portsmouth
2 programs
1
Optilume Urethral DCBPhase 41 trial
Optilume Drug Coated BalloonN/A1 trial
Active Trials
NCT03499964Active Not Recruiting127Est. Mar 2026
NCT05383274Recruiting34Est. Dec 2026
Verona Pharma
Verona PharmaUK - London
1 program
NANOfat graftingN/A1 trial
Active Trials
NCT05464290Unknown25Est. Jan 2023
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
Uroflowmetry with URI CalculationN/A1 trial
Active Trials
NCT07403786Not Yet RecruitingEst. Jul 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
LaborieOptilume Urethral DCB
City TherapeuticsUroflowmetry with URI Calculation
Verona PharmaNANOfat grafting
LaborieOptilume Drug Coated Balloon

Clinical Trials (4)

Total enrollment: 186 patients across 4 trials

NCT05383274LaborieOptilume Urethral DCB

Optilume PoST AppRoval Clinical Evaluation of Andrology ParaMeters

Start: Feb 2022Est. completion: Dec 202634 patients
Phase 4Recruiting
NCT07403786City TherapeuticsUroflowmetry with URI Calculation

Urethral Resistive Index (URI): A New Parameter for Diagnosing Urethral Obstruction

Start: Feb 2026Est. completion: Jul 2026
N/ANot Yet Recruiting
NCT05464290Verona PharmaNANOfat grafting

The Nanofat Regenerative Surgery for Management of Genital Lichen Sclerosus in Male and Female Patients

Start: Jul 2022Est. completion: Jan 202325 patients
N/AUnknown
NCT03499964LaborieOptilume Drug Coated Balloon

ROBUST III- Re-Establishing Flow Via Drug Coated Balloon For The Treatment Of Urethral Stricture Disease

Start: Jun 2018Est. completion: Mar 2026127 patients
N/AActive Not Recruiting

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 186 patients
3 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.