NDAORALCAPSULE
Approved
Apr 2016
Lifecycle
Peak
Competitive Pressure
30/100
Mechanism of Action
12.1 Mechanism of Action Doxycycline is a tetracycline-class antimicrobial drug [see ] . 12.3 Pharmacokinetics Absorption Doxycycline hyclate tablets: Following administration of a single 300 mg dose to adult volunteers, average peak plasma doxycycline levels were 3.0 mcg per mL at 3 hours,…
Indications (21)
Rocky Mountain spotted fevertyphus feverthe typhus groupQ feverrickettsial poxtick fevers caused by Rickettsiaethe following sexually transmitted infections: Uncomplicated urethralendocervicalrectal infections caused by Chlamydia trachomatisthe following respiratory tract infections: Respiratory tract infections caused by Mycoplasma pneumoniaeinfections caused by the following microorganismsbacteriological testing indicates appropriate susceptibility to the drug: Respiratory tract infections caused by Haemophilus influenzaethe following specific bacterial infections: Relapsing fever due to Borrelia recurrentisinfections caused by the following gram-negative microorganismsthe following ophthalmic infections: Trachoma caused by Chlamydia trachomatisalthough the infectious agent is not always eliminatedAnthrax due to Bacillus anthracisincluding inhalational anthrax (post-exposure)malaria due to Plasmodium falciparum in short-term travelers (less than 4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strains [seeincidenceprogression of disease following exposure to aerosolized Bacillus anthracis