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Social Anxiety Disorder

Neurology
12
Pipeline Programs
15
Companies
18
Clinical Trials
2 recruiting
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
3
0
3
4
Early DiscoveryClinical DevelopmentMarket

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.5yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

On Market (1)

Approved therapies currently available

AbbVie
VRAYLARApproved
cariprazine
AbbVie
Atypical Antipsychotic [EPC]oral2015
936M Part D

Competitive Landscape

15 companies ranked by most advanced pipeline stage

Lundbeck
LundbeckDenmark - Copenhagen
2 programs
1
1
EscitalopramPhase 41 trial
CipralexPhase 21 trial
Active Trials
NCT00485888Completed71Est. Aug 2013
NCT00902226Completed30Est. Mar 2010
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
CariprazinePhase 41 trial
Active Trials
NCT05384483Completed40Est. Apr 2024
Alliance Pharmaceuticals
1 program
1
QuetiapinePhase 4
Temple Therapeutics
Temple TherapeuticsNetherlands - Geleen
1 program
1
ParoxetinePhase 31 trial
Active Trials
NCT00074802Completed150Est. May 2008
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
SeroquelPhase 31 trial
Active Trials
NCT00773162Completed21Est. Aug 2013
Pfizer
PfizerNEW YORK, NY
1 program
1
Venlafaxine ERPhase 31 trial
Active Trials
NCT00238719Completed293Est. Jun 2003
ViiV Healthcare
ViiV HealthcareNC - Durham
2 programs
1
1
paroxetinePhase 2
GW679769Phase 1
Oregon Therapeutics
Oregon TherapeuticsFrance - Paris
1 program
1
MDMAPhase 21 trial
Active Trials
NCT05138068Completed90Est. Aug 2025
Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
4 programs
1
ScopolaminePhase 11 trial
Acceptance- and commitment-based behavioral therapyN/A1 trial
Inhibitory Learning-Based ExposureN/A1 trial
Very Brief Exposure to Facial ExpressionsN/A1 trial
Active Trials
NCT00872820Completed50Est. Sep 2013
NCT04048824Completed89Est. Jan 2025
NCT06526260Recruiting80Est. Jul 2026
+1 more trials
GSK
GSKLONDON, United Kingdom
2 programs
GW679769PHASE_11 trial
paroxetinePHASE_21 trial
Active Trials
NCT00332046Completed57
NCT00273039Completed242Est. Sep 2006
UNION therapeutics
UNION therapeuticsDenmark - Hellerup
1 program
Group Cognitive Behavioral TherapyN/A1 trial
Active Trials
NCT07464561Completed34Est. Feb 2026
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
Group Exposure for Social AnxietyN/A1 trial
Active Trials
NCT06673407Recruiting200Est. Oct 2025
Jerusalem Pharmaceuticals
Jerusalem PharmaceuticalsIsrael - Ramallah
1 program
Internet delivered CBT for social anxiety disorderN/A1 trial
Active Trials
NCT03709615Completed120Est. Jun 2020
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Systemic Therapy for Social Anxiety DisorderN/A1 trial
Active Trials
NCT02360033Completed38Est. Sep 2017
Biohaven
BiohavenNEW HAVEN, CT
1 program
BHV-0223PHASE_2_31 trial
Active Trials
NCT03017508Completed22Est. Jan 2021

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
AbbVieCariprazine
LundbeckEscitalopram
AstraZenecaSeroquel
Temple TherapeuticsParoxetine
PfizerVenlafaxine ER
BiohavenBHV-0223
Oregon TherapeuticsMDMA
LundbeckCipralex
GSKparoxetine
Angeles TherapeuticsScopolamine
GSKGW679769
Angeles TherapeuticsVery Brief Exposure to Facial Expressions
Colorado TherapeuticsGroup Exposure for Social Anxiety
UNION therapeuticsGroup Cognitive Behavioral Therapy
Jerusalem PharmaceuticalsInternet delivered CBT for social anxiety disorder

Showing 15 of 18 trials with date data

Clinical Trials (18)

Total enrollment: 1,687 patients across 18 trials

Cariprazine Versus Placebo for Social Anxiety Disorder

Start: Jul 2022Est. completion: Apr 202440 patients
Phase 4Completed

Escitalopram in Patients With Social Anxiety Disorder

Start: Mar 2009Est. completion: Mar 201030 patients
Phase 4Completed

Flushing in Social Anxiety Disorder on Seroquel

Start: Oct 2008Est. completion: Aug 201321 patients
Phase 3Completed

Adding Cognitive Behavioral Therapy to Drug Treatment for Social Anxiety Disorder

Start: Dec 2003Est. completion: May 2008150 patients
Phase 3Completed
NCT00238719PfizerVenlafaxine ER

Study Evaluating Venlafaxine ER in Children and Adolescents With Social Anxiety Disorder

Start: Dec 1999Est. completion: Jun 2003293 patients
Phase 3Completed

Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder

Start: Jan 2017Est. completion: Jan 202122 patients
Phase 2/3Completed

Social Anxiety MDMA-Assisted Therapy Investigation

Start: Apr 2022Est. completion: Aug 202590 patients
Phase 2Completed

Flushing in Social Anxiety Disorder on Cipralex

Start: Oct 2008Est. completion: Aug 201371 patients
Phase 2Completed
NCT00273039GSKparoxetine

A Study Of A New Medicine (GW679769) For The Treatment Of Social Anxiety Disorder

Start: Aug 2005Est. completion: Sep 2006242 patients
Phase 2Completed

Generalization of Extinction Learning

Start: Aug 2013Est. completion: Aug 201760 patients
Phase 1Completed

fMRI Study Comparing BOLD Activation Patterns Using GW679769 In Subjects With Social Anxiety Disorder

Start: Jan 200657 patients
Phase 1Completed
NCT06526260Angeles TherapeuticsVery Brief Exposure to Facial Expressions

Very Brief Exposure: Development of a Novel Exposure Modality for Social Anxiety Disorder in Transition-Age Youth

Start: Aug 2024Est. completion: Jul 202680 patients
N/ARecruiting
NCT06673407Colorado TherapeuticsGroup Exposure for Social Anxiety

Group Exposure Workshops for Socially Anxious Undergraduates

Start: Jun 2024Est. completion: Oct 2025200 patients
N/ARecruiting
NCT07464561UNION therapeuticsGroup Cognitive Behavioral Therapy

RESCCUE4 - Group CBT for Social Anxiety in Adolescents

Start: May 2024Est. completion: Feb 202634 patients
N/ACompleted
NCT03709615Jerusalem PharmaceuticalsInternet delivered CBT for social anxiety disorder

Therapeutic Processes in iCBT for SAD

Start: Dec 2017Est. completion: Jun 2020120 patients
N/ACompleted
NCT04048824Angeles TherapeuticsInhibitory Learning-Based Exposure

Optimizing Exposure Therapy for Anxiety Disorders

Start: Aug 2015Est. completion: Jan 202589 patients
N/ACompleted
NCT02360033Heidelberg PharmaSystemic Therapy for Social Anxiety Disorder

Systemic Therapy and Cognitive Behavioral Therapy for Social Anxiety Disorders

Start: Jan 2015Est. completion: Sep 201738 patients
N/ACompleted
NCT00872820Angeles TherapeuticsAcceptance- and commitment-based behavioral therapy

Examining Long-Term Effects and Neural Mediators of Behavioral Treatments for Social Anxiety Disorder

Start: Oct 2008Est. completion: Sep 201350 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

3 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 1,687 patients
15 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.