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Relapsing-remitting Multiple Sclerosis (RRMS)

Neurology
7
Pipeline Programs
11
Companies
11
Clinical Trials
2 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
2
0
0
0
5
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
4100%
+ 10 programs with unclassified modality

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.6yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

Competitive Landscape

10 companies ranked by most advanced pipeline stage

Sandoz
SandozAustria - Kundl
2 programs
1
1
fingolimodPhase 31 trial
CLS12311 lowPhase 11 trial
Active Trials
NCT06430671Active Not Recruiting11Est. Dec 2025
NCT01633112Terminated1,064Est. Apr 2018
Biocad
BiocadRussia - St. Petersburg
1 program
1
BCD-281Phase 31 trial
Active Trials
NCT07321093Recruiting292Est. Dec 2028
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
DaclizumabPhase 3Monoclonal Antibody
Polpharma Biologics
Polpharma BiologicsNetherlands - Amsterdam
1 program
1
IntravenousPhase 31 trial
Active Trials
NCT04115488Completed265Est. Feb 2022
Amgen
AmgenTHOUSAND OAKS, CA
1 program
1
OcrelizumabPhase 3Monoclonal Antibody1 trial
Active Trials
NCT06700343Recruiting444Est. Dec 2027
Cellerys
CellerysSwitzerland - Schlileren
1 program
1
CLS12311 lowPhase 1
Biogen
BiogenCAMBRIDGE, MA
4 programs
NatalizumabN/AMonoclonal Antibody1 trial
DaclizumabPHASE_3Monoclonal Antibody1 trial
peginterferon beta-1aPHASE_41 trial
peginterferon beta-1aPHASE_41 trial
Active Trials
NCT05304520Completed318Est. Apr 2024
NCT02881567Terminated41Est. Sep 2018
NCT02587065Completed193Est. Dec 2017
+1 more trials
GE HealthCare
1 program
Arm 1 - GEH120714PHASE_11 trial
Active Trials
NCT01738347Completed30Est. May 2016
Immunic Therapeutics
Immunic TherapeuticsGermany - Grafelfing
1 program
IMU-838PHASE_21 trial
Active Trials
NCT03846219Active Not Recruiting210Est. Dec 2029
Novartis
NovartisBASEL, Switzerland
1 program
fingolimodPHASE_3

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Biogenpeginterferon beta-1a
Biogenpeginterferon beta-1a
BiocadBCD-281
AmgenOcrelizumab
Polpharma BiologicsIntravenous
BiogenDaclizumab
Sandozfingolimod
Immunic TherapeuticsIMU-838
SandozCLS12311 low
GE HealthCareArm 1 - GEH120714
BiogenNatalizumab

Clinical Trials (11)

Total enrollment: 2,868 patients across 11 trials

NCT02587065Biogenpeginterferon beta-1a

Plegridy Satisfaction Study in Participants

Start: Feb 2016Est. completion: Dec 2017193 patients
Phase 4Completed
NCT02568111Biogenpeginterferon beta-1a

Brimonidine Tartrate for the Treatment of Injection Related Erythema

Start: Feb 2016Est. completion: Aug 20160
Phase 4Withdrawn

A Study of the Efficacy and Safety of BCD-281 in Patients With Relapsing-Remitting Multiple Sclerosis

Start: Nov 2025Est. completion: Dec 2028292 patients
Phase 3Recruiting
NCT06700343AmgenOcrelizumab

Comparison Between ABP 692 and Ocrevus® (Ocrelizumab)

Start: Jan 2025Est. completion: Dec 2027444 patients
Phase 3Recruiting

Efficacy and Safety of the Biosimilar Natalizumab PB006 in Comparison to Tysabri®

Start: Oct 2019Est. completion: Feb 2022265 patients
Phase 3Completed

Efficacy and Safety of Daclizumab in Participants With RRMS Switching From Natalizumab

Start: Apr 2017Est. completion: Sep 201841 patients
Phase 3Terminated

MS Study Evaluating Safety and Efficacy of Two Doses of Fingolimod Versus Copaxone

Start: Aug 2012Est. completion: Apr 20181,064 patients
Phase 3Terminated

MRI Trial to exPlore the efficAcy and Safety of IMU-838 in Relapsing Remitting Multiple Sclerosis (EMPhASIS)

Start: Jan 2019Est. completion: Dec 2029210 patients
Phase 2Active Not Recruiting
NCT06430671SandozCLS12311 low

Peptide-coupled Red Blood Cells for the Treatment of Multiple Sclerosis

Start: Jun 2024Est. completion: Dec 202511 patients
Phase 1Active Not Recruiting
NCT01738347GE HealthCareArm 1 - GEH120714

Assess Safety, Bio-distribution, Radiation Dosimetry and Optimize the Imaging Protocol of GEH120714 (18F) Injection in Healthy Volunteers and Participants With Relapsing and Remitting Multiple Sclerosis (rrMS).

Start: Apr 2013Est. completion: May 201630 patients
Phase 1Completed

A Study for Tysabri Participant Preference

Start: Oct 2021Est. completion: Apr 2024318 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

5 late-stage (Phase 3) programs, potential near-term approvals
2 actively recruiting trials targeting 2,868 patients
11 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.