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Relapsing Multiple Sclerosis

Neurology
18
Pipeline Programs
17
Companies
36
Clinical Trials
11 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
2
0
10
5
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1869%
Small Molecule
519%
Cell Therapy
28%
Vaccine
14%
+ 23 programs with unclassified modality

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.6yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

Competitive Landscape

16 companies ranked by most advanced pipeline stage

Sandoz
SandozAustria - Kundl
23 programs
1
1
10
4
FingolimodPhase 4
OfatumumabPhase 4Monoclonal Antibody
OfatumumabPhase 4Monoclonal Antibody
Quadrivalent influenza vaccinePhase 4Vaccine
FTY720Phase 3
+18 more programs
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
1 program
1
OzanimodPhase 41 trial
Active Trials
NCT06529406Recruiting100Est. Aug 2029
Genentech
GenentechCA - Oceanside
1 program
1
FenebrutinibPhase 2Small Molecule1 trial
Active Trials
NCT07161258Recruiting12Est. Feb 2029
Merck & Co.
Merck & Co.RAHWAY, NJ
5 programs
RebifN/A1 trial
Atacicept 25 mgPHASE_21 trial
Rebif New Formulation + prophylactic IbuprofenPHASE_3Small Molecule1 trial
TeriflunomidePHASE_31 trial
TeriflunomidePHASE_31 trial
Active Trials
NCT01601119Completed545Est. Jul 2014
NCT00853762Terminated74Est. Feb 2011
NCT00619307Completed117Est. Apr 2008
+2 more trials
Biogen
BiogenCAMBRIDGE, MA
5 programs
natalizumabN/AMonoclonal Antibody1 trial
CDP323PHASE_1_21 trial
BIIB017PHASE_31 trial
BIIB017PHASE_31 trial
peginterferon beta-1aPHASE_35 trials
Active Trials
NCT01070836Completed35,895Est. Nov 2015
NCT00726648Completed71Est. Mar 2009
NCT00906399Completed1,516Est. Oct 2013
+6 more trials
TG Therapeutics
TG TherapeuticsNEW YORK, NY
3 programs
UblituximabPHASE_2_3Monoclonal Antibody1 trial
UblituximabPHASE_3Monoclonal Antibody1 trial
UblituximabPHASE_3Monoclonal Antibody1 trial
Active Trials
NCT07220252Not Yet Recruiting240Est. Jun 2033
NCT05877963Recruiting800Est. Dec 2027
NCT07211633Recruiting360Est. Dec 2028
Teva
TevaIsrael - Petach Tikva
2 programs
LaquinimodPHASE_31 trial
LaquinimodPHASE_34 trials
Active Trials
NCT01047319Terminated1,047Est. Jun 2017
NCT02284568Completed374Est. Oct 2017
NCT02085863Completed40Est. Nov 2014
+2 more trials
Providence Therapeutics
1 program
Cerebrospinal and Blood Serum Semaphorin 4A LevelsN/A
Bristol Myers Squibb
1 program
Cerebrospinal and Blood Serum Semaphorin 4A LevelsN/A1 trial
Active Trials
NCT05077956Withdrawn0Est. Oct 2023
Cinnagen
CinnagenIran - Tehran
1 program
Glatiramer AcetateN/A1 trial
Active Trials
NCT04928313Completed368Est. Feb 2020
UCB Pharma
UCB PharmaBelgium - Brussels
1 program
CDP323PHASE_1_2
Novartis
NovartisBASEL, Switzerland
1 program
rapcabtagene autoleucelPHASE_1_2Cell Therapy5 trials
Active Trials
NCT07443137Not Yet Recruiting20Est. Aug 2028
NCT07048197Recruiting27Est. Nov 2028
NCT06868290Recruiting126Est. May 2030
+2 more trials
Zenas BioPharma
Zenas BioPharmaWALTHAM, MA
1 program
ObexelimabPHASE_2Monoclonal Antibody1 trial
Active Trials
NCT06564311Active Not Recruiting93Est. Feb 2026
Clene
CleneSALT LAKE CITY, UT
1 program
CNM-Au8PHASE_2_31 trial
Active Trials
NCT04626921Completed55Est. Sep 2023
Roche
RocheSTAVANGER NORWAY, Norway
1 program
FenebrutinibPHASE_3Small Molecule
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
1 program
Dimethyl Fumarate Enteric-coated CapsulesPHASE_41 trial
Active Trials
NCT07138833Not Yet Recruiting50Est. Aug 2028

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Qilu PharmaceuticalDimethyl Fumarate Enteric-coated Capsules
Colorado TherapeuticsOzanimod
Biogenpeginterferon beta-1a
TG TherapeuticsUblituximab
TG TherapeuticsUblituximab
Merck & Co.Teriflunomide
Merck & Co.Teriflunomide
Biogenpeginterferon beta-1a
BiogenBIIB017
Biogenpeginterferon beta-1a
TevaLaquinimod
TevaLaquinimod
BiogenBIIB017
Merck & Co.Rebif New Formulation + prophylactic Ibuprofen
TG TherapeuticsUblituximab

Showing 15 of 36 trials with date data

Clinical Trials (36)

Total enrollment: 48,545 patients across 36 trials

NCT07138833Qilu PharmaceuticalDimethyl Fumarate Enteric-coated Capsules

A Phase IV Study of Dimethyl Fumarate Enteric-coated Capsules for Relapsing Multiple Sclerosis (RMS)

Start: Sep 2025Est. completion: Aug 202850 patients
Phase 4Not Yet Recruiting

Prospective Evaluation of Sequencing From antiCD-20 Therapies to Ozanimod

Start: Jul 2024Est. completion: Aug 2029100 patients
Phase 4Recruiting
NCT02234869Biogenpeginterferon beta-1a

Transition to Peginterferon Beta-1a (BIIB017) From Subcutaneous Interferon Therapy

Start: Oct 2014Est. completion: Mar 20180
Phase 4Withdrawn

A Study to Evaluate the Pharmacokinetics, Pharmacodynamics, Safety, Radiological and Clinical Effects of Subcutaneous Ublituximab in Participants With Relapsing Multiple Sclerosis (RMS)

Start: Jul 2025Est. completion: Dec 2028360 patients
Phase 3Recruiting

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

Start: Jun 2023Est. completion: Dec 2027800 patients
Phase 3Recruiting

Study of Evobrutinib in Participants With RMS (evolutionRMS 2)

Start: Jul 2020Est. completion: Mar 20241,166 patients
Phase 3Terminated

Study of Evobrutinib in Participants With RMS (evolutionRMS 1)

Start: Jun 2020Est. completion: Mar 20241,124 patients
Phase 3Terminated
NCT03958877Biogenpeginterferon beta-1a

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

Start: Oct 2019Est. completion: May 2027152 patients
Phase 3Active Not Recruiting

Characterize Flu-like Symptoms in Relapsing Multiple Sclerosis Patients Transitioning From Non-Pegylated Interferon Beta (IFN-β) Therapies to Peginterferon Beta-1a (BIIB017)

Start: Nov 2013Est. completion: Nov 2015251 patients
Phase 3Completed
NCT01332019Biogenpeginterferon beta-1a

Long-Term Safety and Efficacy Study of Peginterferon Beta-1a

Start: Apr 2011Est. completion: Oct 20151,077 patients
Phase 3Completed
NCT01047319TevaLaquinimod

A Study to Evaluate the Long-term Safety, Tolerability and Effect of Daily Oral Laquinimod 0.6 mg on Disease Course in Subjects With Relapsing Multiple Sclerosis

Start: May 2010Est. completion: Jun 20171,047 patients
Phase 3Terminated
NCT00988052TevaLaquinimod

A Study To Evaluate the Long-Term Safety, Tolerability and Effect on Disease Course

Start: Nov 2009Est. completion: Jul 2017839 patients
Phase 3Terminated

Efficacy and Safety Study of Peginterferon Beta-1a in Participants With Relapsing Multiple Sclerosis

Start: Jun 2009Est. completion: Oct 20131,516 patients
Phase 3Completed
NCT00619307Merck & Co.Rebif New Formulation + prophylactic Ibuprofen

Transition to Rebif New Formulation

Start: Jul 2007Est. completion: Apr 2008117 patients
Phase 3Completed

Study to Assess Effects of Ublituximab in Pediatric Participants With Relapsing Forms of Multiple Sclerosis

Start: Jun 2026Est. completion: Jun 2033240 patients
Phase 2/3Not Yet Recruiting

A Multi-Center, Open-Label Long-Term Extension Study of CNM-Au8 In Patients With Stable Relapsing Multiple Sclerosis

Start: Oct 2020Est. completion: Sep 202355 patients
Phase 2/3Completed

A Pharmacokinetics (PK), Pharmacodynamics (PD), Safety and Tolerability Study of Fenebrutinib in Children and Adolescents With Relapsing Multiple Sclerosis (RMS)

Start: Oct 2025Est. completion: Feb 202912 patients
Phase 2Recruiting
NCT06868290Novartisrapcabtagene autoleucel

Phase 2 Study Evaluating Rapcabtagene Autoleucel in Participants With Severe Active GPA or MPA

Start: Mar 2025Est. completion: May 2030126 patients
Phase 2Recruiting
NCT06665256Novartisrapcabtagene autoleucel

Phase 2 Study of Rapcabtagene Autoleucel in Myositis

Start: Dec 2024Est. completion: Jul 2030123 patients
Phase 2Recruiting
NCT06581198Novartisrapcabtagene autoleucel

A Study of Rapcabtagene Autoleucel in Active, Refractory Systemic Lupus Erythematosus (SLE) or Lupus Nephritis (LN) Patients (AUTOGRAPH - SLE/LN)

Start: Sep 2024Est. completion: Feb 2032179 patients
Phase 2Recruiting

A Study of Obexelimab in Patients With Relapsing Multiple Sclerosis (MoonStone)

Start: Aug 2024Est. completion: Feb 202693 patients
Phase 2Active Not Recruiting
NCT02284568TevaLaquinimod

A Phase 2 Clinical Study in Subjects With Primary Progressive Multiple Sclerosis to Assess the Efficacy, Safety and Tolerability of Two Oral Doses of Laquinimod Either of 0.6 mg/Day or 1.5mg/Day (Experimental Drug) as Compared to Placebo

Start: Jan 2015Est. completion: Oct 2017374 patients
Phase 2Completed
NCT01404117TevaLaquinimod

A Multinational, Randomized, Double-blind, Parallel-group, Placebo-controlled Study Assessing the Safety and Tolerability

Start: Mar 2012Est. completion: Jan 20140
Phase 2Withdrawn
NCT00853762Merck & Co.Atacicept 25 mg

Atacicept in Multiple Sclerosis Extension Study, Phase II

Start: Mar 2009Est. completion: Feb 201174 patients
Phase 2Terminated
NCT07048197Novartisrapcabtagene autoleucel

A Study to Assess Safety, Cellular Kinetics and Exploratory Efficacy of Rapcabtagene Autoleucel in Rheumatoid Arthritis and Sjogren's Disease

Start: Jun 2025Est. completion: Nov 202827 patients
Phase 1/2Recruiting
NCT06617793Novartisrapcabtagene autoleucel

An Open-label Study to Assess the Safety, Efficacy, and Cellular Kinetics of YTB323 in Relapsing Multiple Sclerosis

Start: Feb 2025Est. completion: Oct 203028 patients
Phase 1/2Recruiting
NCT06675864Novartisrapcabtagene autoleucel

Open-label, Multi-center, Phase I/II Study to Assess Safety, Disease Progression and Cellular Kinetics Following YTB323 Administration in Participants With Non-active Progressive Multiple Sclerosis (PMS)

Start: Dec 2024Est. completion: Jun 203028 patients
Phase 1/2Recruiting

CDP323 Biomarker Study

Start: Jul 2008Est. completion: Mar 200971 patients
Phase 1/2Completed
NCT07443137Novartisrapcabtagene autoleucel

CAR-T ceLL for Eradication of Active Residual Disease in LBCL (CLEAR-1 Study)

Start: May 2026Est. completion: Aug 202820 patients
Phase 1Not Yet Recruiting
NCT02085863TevaLaquinimod

A Phase I Study in Young Healthy Women to Investigate the Effects of Laquinimod on Standard Oral Contraceptive When Both Treatments Are Given Together

Start: Feb 2014Est. completion: Nov 201440 patients
Phase 1Completed
NCT05077956Bristol Myers SquibbCerebrospinal and Blood Serum Semaphorin 4A Levels

Sema 4A as a Marker for Inflammatory Disease in Multiple Sclerosis

Start: Oct 2021Est. completion: Oct 20230
N/AWithdrawn
NCT05688436Biogenpeginterferon beta-1a

A Study to Learn More About The Safety of Diroximel Fumarate (VUMERITY®) in Participants Who Took it During Pregnancy And About the Health of Their Babies

Start: Sep 2021Est. completion: Jan 20311,178 patients
N/ARecruiting
NCT04655222Biogenpeginterferon beta-1a

Study to Investigate Pregnancy Outcomes in Female Participants Exposed to Subcutaneous (SC) Peginterferon Beta-1a and Intramuscular (IM) Interferon Beta-1a Reported in a German Participant Support Program

Start: Apr 2021Est. completion: Oct 2021470 patients
N/ACompleted
NCT04928313CinnagenGlatiramer Acetate

Safety and Effectiveness of Cinnomer® (Glatiramer Acetate) in Multiple Sclerosis (MS) Treatment in Iran

Start: Apr 2015Est. completion: Feb 2020368 patients
N/ACompleted

Impact of Disease Modifying Therapies (DMTs) and Associated Support Services in Relapsing Multiple Sclerosis (RMS) Patients

Start: Jan 2012Est. completion: Jul 2014545 patients
N/ACompleted

JC Virus Antibody Study of Participants With Relapsing Forms of MS Receiving Treatment With Natalizumab

Start: Mar 2010Est. completion: Nov 201535,895 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

10 late-stage (Phase 3) programs, potential near-term approvals
11 actively recruiting trials targeting 48,545 patients
17 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.