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Partial Seizures

Neurology
5
Pipeline Programs
4
Companies
10
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
0
0
0
4
1
Early DiscoveryClinical DevelopmentMarket

Neurology is a $26.9B market dominated by a single blockbuster anticoagulant (ELIQUIS), representing a mature but consolidating therapeutic area.

$26.9B marketMature→ Stable30 products15 companies

Key Trends

  • Extreme market concentration: 68% of spending driven by one FXa inhibitor product
  • Psychiatric and migraine therapies emerging as secondary growth drivers
  • High clinical trial activity (8,279 trials) signals continued pipeline development

Career Verdict

Neurology offers solid career stability with good hiring demand, but limited upside growth—best suited for professionals seeking established market positions rather than emerging-area innovation.

AI-generated market analysis based on FDA, CMS, ClinicalTrials.gov, and hiring data

Market Leaders

#1ELIQUISStable
$18.3B
Bristol Myers Squibb·Launch15.0yr
$1.8B
#3BRILINTAStable
$692M
AstraZeneca·Peak10.2yr
#4NUPLAZIDStable
$596M
$530M
Johnson & Johnson·Peak15.6yr

Drug Class Breakdown

FXa Inhibitors (anticoagulant)
$18.3B(68%)

market-defining single product

Dopamine/Serotonin Antagonists (psychiatric)
$2.4B(9%)

stable mature class

P2Y12 Receptor Antagonists (antiplatelet)
$692M(3%)

niche but stable

5-HT2A Inverse Agonists (psychiatric)
$596M(2%)

specialty indication focus

CGRP Receptor Antagonists (migraine)
$931M(3%)

emerging growth segment

Immunomodulators (MS)
$747M(3%)

stable with LOE risk

Other mechanisms
$2.6B(10%)

diverse small products

Career Outlook

Stable

Neurology represents a mature, cash-generative market with limited growth tailwinds but strong hiring stability. The dominance of ELIQUIS creates a bifurcated career landscape: high-opportunity positions in emerging segments (CGRP antagonists, psychiatric therapeutics) and commoditized roles in anticoagulant franchises. Job availability is solid but growth expectations should be tempered relative to oncology or immunology.

Breaking In

Entry-level professionals should target clinical operations or commercial support roles at J&J, AstraZeneca, or Sanofi to build domain expertise in neurology disease states and competitive dynamics.

For Experienced Professionals

Experienced professionals should prioritize emerging mechanism roles (CGRP, tau-targeting programs) or pivot to medtech/neurotech (Stryker, Medtronic) to capture higher growth and salary potential than traditional pharma incumbents.

In-Demand Skills

Medical Science Liaisons (MSL) for specialist engagementClinical trial operations expertisePsychiatric/neurodegenerative disease educationRegulatory affairs (given patent cliff activity)Commercial strategy around branded/generic transitions

Best For

Medical Science LiaisonCommercial Brand Manager (anticoagulant/psychiatric franchises)Clinical Operations ManagerRegulatory Affairs SpecialistClinical Development Manager (CGRP/immunomodulator pipelines)

Hiring Landscape

$100K-$199K

Neurology shows moderate but distributed hiring across pharma and medtech employers, with 4,186 total jobs listed. Commercial functions lead (947 roles, $169K avg), followed by clinical operations (467 roles, $132K avg), indicating bias toward commercialization over R&D. Takeda leads external hiring (762 jobs) with strong representation in contract research and CRO spaces.

4,186
Open Roles
5
Companies Hiring
5
Departments

Top Hiring Companies

762Growing
434Stable
302Stable

By Department

Commercial(23%)
$169K
Clinical Operations(11%)
$132K
Engineering(8%)
$199K
IT(4%)
$100K
Manufacturing(3%)
$170K

Commercial and clinical operations roles dominate, offering stable mid-career positions; engineering roles command premium salaries ($199K), suggesting strong device/neurotech hiring pockets.

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
4 programs
3
1
PregabalinPhase 41 trial
pregabalinPhase 31 trial
pregabalinPhase 31 trial
pregabalinPhase 31 trial
Active Trials
NCT01262677Completed325Est. Aug 2012
NCT00141258Completed178Est. Aug 2006
NCT00537238Completed509Est. May 2012
+1 more trials
Abbott
AbbottABBOTT PARK, IL
1 program
1
Divalproex SodiumPhase 31 trial
Active Trials
NCT00102713Completed50
Eisai
EisaiChina - Liaoning
4 programs
PerampanelN/A1 trial
ZonisamidePHASE_31 trial
ZonisamidePHASE_31 trial
Adjunctive ZonisamidePHASE_41 trial
Active Trials
NCT04257604Completed243Est. Apr 2019
NCT01136954Completed144Est. Mar 2012
NCT00327717Completed240Est. May 2008
+1 more trials
UCB Pharma
UCB PharmaBelgium - Brussels
1 program
LevetiracetamPHASE_31 trial
Active Trials
NCT03340064Completed38Est. Jul 2023

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
EisaiAdjunctive Zonisamide
PfizerPregabalin
UCB PharmaLevetiracetam
Pfizerpregabalin
EisaiZonisamide
Pfizerpregabalin
EisaiZonisamide
Pfizerpregabalin
AbbottDivalproex Sodium
EisaiPerampanel

Clinical Trials (10)

Total enrollment: 2,063 patients across 10 trials

NCT01630057EisaiAdjunctive Zonisamide

Evaluation of the Efficacy and Safety of Adjunctive Zonisamide vs Replacement With Zonisamide of the Last Added Antiepileptic Drug

Start: Sep 2009Est. completion: Jul 2012200 patients
Phase 4Completed

Pregabalin In Partial Seizures (PREPS): An Open-Label, Multicenter Add On Therapy Trial

Start: Mar 2007Est. completion: Aug 2009136 patients
Phase 4Terminated

A Study of Levetiracetam as Monotherapy or Adjunctive Treatment of Partial Seizures in Pediatric Epileptic Subjects Ranging From 1 Month to Less Than 4 Years of Age

Start: Nov 2017Est. completion: Jul 202338 patients
Phase 3Completed

Once-A-Day Pregabalin For Partial Seizures

Start: Feb 2011Est. completion: Aug 2012325 patients
Phase 3Completed

A Study to Assess the Efficacy and Safety of Adjunctive Zonisamide in Paediatric Partial Onset Seizures (CATZ Extension Study)

Start: Jul 2008Est. completion: Mar 2012144 patients
Phase 3Completed

Pregabalin Versus Levetiracetam In Partial Seizures

Start: Oct 2007Est. completion: May 2012509 patients
Phase 3Completed

Evaluating the Efficacy and Safety of Zonisamide in the Treatment of Partial Seizures

Start: Sep 2006Est. completion: May 2008240 patients
Phase 3Completed

Pregabalin Epilepsy Add-On Trial

Start: Oct 2005Est. completion: Aug 2006178 patients
Phase 3Completed
NCT00102713AbbottDivalproex Sodium

A Study for Treatment of Partial Seizures in Children

Start: Feb 200550 patients
Phase 3Completed

A Study of Perampanel as Add-on Therapy in Adult and Adolescent Participants With Focal Seizures

Start: Jan 2016Est. completion: Apr 2019243 patients
N/ACompleted

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

4 late-stage (Phase 3) programs, potential near-term approvals
4 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.