Moderate to Severe Ulcerative Colitis

Immunology
2
Pipeline Programs
2
Companies
2
Clinical Trials
1 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Monoclonal Antibody
1100%
+ 1 programs with unclassified modality

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Connect Biopharma
Connect BiopharmaSAN DIEGO, CA
1 program
1
Double-Blind 0.2mg CBP-307Phase 21 trial
Active Trials
NCT04700449CompletedEst. Nov 2022
Genentech
GenentechCA - Oceanside
1 program
1
VixarelimabPhase 1/2Monoclonal Antibody1 trial
Active Trials
NCT06693908Recruiting24Est. Jun 2026

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
Connect BiopharmaDouble-Blind 0.2mg CBP-307
GenentechVixarelimab

Clinical Trials (2)

Total enrollment: 24 patients across 2 trials

NCT04700449Connect BiopharmaDouble-Blind 0.2mg CBP-307

A Study Assessing the Efficacy and Safety of CBP-307 in Subjects With Moderate to Severe Ulcerative Colitis (UC)

Start: Feb 2019Est. completion: Nov 2022
Phase 2Completed

A Study to Evaluate the Activity, and Safety of Vixarelimab in Participants With Moderate to Severe Active Ulcerative Colitis

Start: Mar 2025Est. completion: Jun 202624 patients
Phase 1/2Recruiting

Related Jobs in Immunology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 actively recruiting trials targeting 24 patients
Monoclonal Antibody is the dominant modality (100% of programs)
2 companies competing in this space