NDASUBCUTANEOUSSOLUTIONPriority Review
Approved
May 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20
Data completeness
6/8 — Strong
Priority Review
MOUNJARO (tirzepatide) by Eli Lilly and Company is g-protein-linked receptor interactions [moa]. Approved for glucose-dependent insulinotropic polypeptide receptor agonist [epc]. First approved in 2022.
Drug data last refreshed 20h ago · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
MOUNJARO (tirzepatide) is a subcutaneous solution approved by the FDA on May 13, 2022, developed by Eli Lilly and Company. It is a dual glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist that works through G-protein-linked receptor interactions. MOUNJARO is indicated for type 2 diabetes management and represents a mechanistically distinct approach to glycemic control by simultaneously activating two incretin pathways, offering enhanced glucose-dependent insulin secretion.
$2.4BPart D
15.7 years to LOEMechanism of Action
G-Protein-linked Receptor Interactions
Pharmacologic Class:
Glucose-dependent Insulinotropic Polypeptide Receptor Agonist
Indications
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Clinical Trials (20)
Safety and Efficacy of NA-931 and Tirzepatide in Adults Who Are Overweight or Obese
Started Aug 2026
224 enrolled
Obesity and Overweight
A Study of Tirzepatide (LY3298176) in Adult Participants in India With Either Type 2 Diabetes Mellitus or Obesity
Started Feb 2026
344 enrolled
Diabetes Mellitus, Type 2ObesityOverweight
Tirzepatide in Idiopathic Intracranial Hypertension Trial
Started Feb 2026
60 enrolled
Idiopathic Intracranial Hypertension (IIH)
A Study to Evaluate the Effect of Fasting Duration and Tirzepatide Withholding on the Amount of Food and Fluid in the Stomach in Participants With Type 2 Diabetes Mellitus and Participants With Overweight or Obesity Without Type 2 Diabetes Mellitus
Started Jan 2026
40 enrolled
Diabetes Mellitus, Type 2OverweightObesity
A Trial Within Cohort Feasibility Study Design Comparing Standard of Care Versus Weight Loss (Achieved Through Tirzepatide) for Obesity-related Hypertension in Young Adults
Started Jan 2026
60 enrolled
HypertensionObesity & Overweight
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.