Chemotherapy-Induced Peripheral Neuropathy

Neurology
3
Pipeline Programs
4
Companies
5
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
2
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

4 companies ranked by most advanced pipeline stage

Veloxis Pharmaceuticals
2 programs
1
1
thrombomodulin alfaPhase 21 trial
thrombomodulin alfaPhase 11 trial
Active Trials
NCT05251727TerminatedEst. Jun 2024
NCT04492436WithdrawnEst. Jul 2024
WinSanTor
WinSanTorCA - San Diego
1 program
1
WST-057 ActivePhase 21 trial
Active Trials
NCT05488873Active Not RecruitingEst. May 2026
Heidelberg Pharma
Heidelberg PharmaGermany - Ladenburg
1 program
Limb hypothermiaN/A1 trial
Active Trials
NCT06541769Completed122Est. Jul 2022
Knight Therapeutics
Knight TherapeuticsQC - Montréal
1 program
Whole Body VibrationN/A1 trial
Active Trials
NCT04170075Completed38Est. Dec 2022

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
WinSanTorWST-057 Active
Veloxis Pharmaceuticalsthrombomodulin alfa
Veloxis Pharmaceuticalsthrombomodulin alfa
Heidelberg PharmaLimb hypothermia
Knight TherapeuticsWhole Body Vibration

Clinical Trials (5)

Total enrollment: 160 patients across 5 trials

NCT05488873WinSanTorWST-057 Active

A Study of Topical Pirenzepine or Placebo in Oncology Patients With Chemotherapy Induced Peripheral Neuropathy

Start: Nov 2022Est. completion: May 2026
Phase 2Active Not Recruiting
NCT04492436Veloxis Pharmaceuticalsthrombomodulin alfa

A Trial Measuring ART-123 Ability to Prevent Sensory Neuropathy in Unresectable mCRC Subjects w/Oxaliplatin-based Chemo

Start: Oct 2021Est. completion: Jul 2024
Phase 2Withdrawn
NCT05251727Veloxis Pharmaceuticalsthrombomodulin alfa

Assess Safety and Tolerability of ART-123 + FOLFOX + Bevacizumab in Metastatic Colorectal Cancer Patients

Start: Mar 2022Est. completion: Jun 2024
Phase 1Terminated
NCT06541769Heidelberg PharmaLimb hypothermia

CIPN-prevention Trial Evaluating the Efficacy of Hand-cooling and Hand-compression

Start: Oct 2019Est. completion: Jul 2022122 patients
N/ACompleted
NCT04170075Knight TherapeuticsWhole Body Vibration

Whole Body Vibration for the Improvement of Health and Functioning in Participants With Chemotherapy-Induced Peripheral Neuropathy

Start: Aug 2019Est. completion: Dec 202238 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

4 companies competing in this space

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