Acute Migraine

Neurology
4
Pipeline Programs
3
Companies
3
Clinical Trials
1
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
1
1
Early DiscoveryClinical DevelopmentMarket

On Market (1)

Approved therapies currently available

U
RIMEGEPANTApproved
rimegepant
Unknown Company
oral

Competitive Landscape

3 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
1 program
1
RimegepantPhase 31 trial
Active Trials
NCT04574362CompletedEst. Dec 2021
Kallyope
KallyopeNY - New York
1 program
1
ElismetrepPhase 21 trial
Active Trials
NCT06848075CompletedEst. Aug 2025
Teva
TevaIsrael - Petach Tikva
1 program
1
PROT-CL-NP101-015.01Phase 11 trial
Active Trials
NCT02684409Completed37Est. Nov 2014

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerRimegepant
KallyopeElismetrep
TevaPROT-CL-NP101-015.01

Clinical Trials (3)

Total enrollment: 37 patients across 3 trials

Safety and Efficacy Trial of BHV3000 (Rimegepant) 75 mg for the Acute Treatment of Migraine

Start: Oct 2020Est. completion: Dec 2021
Phase 3Completed

A Phase IIb, Randomized, Double-Blind, Placebo-Controlled Study of Elismetrep (K-304) in the Treatment of Migraine

Start: Mar 2025Est. completion: Aug 2025
Phase 2Completed
NCT02684409TevaPROT-CL-NP101-015.01

Safety, Pharmacokinetic, and Tolerability Study of Zecuity® in Adolescent Subjects With a History of Acute Migraine

Start: Aug 2013Est. completion: Nov 201437 patients
Phase 1Completed

Related Jobs in Neurology

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space