HeartFlow(HTFL)

SAN FRANCISCO, CABiotechnology1 H-1B visas (FY2023)

Focus: HeartFlow is a public biotechnology company specializing in AI-enabled coronary heart disease assessment, focused on non-invasive diagnostic solutions for coronary artery disease evaluation. The company operates in the high-value cardiovascular diagnostics market with a public market presence (NASDAQ: HTFL).

Cardiovascular Metabolic Diseases

Profile data last refreshed 2h ago · AI intelligence enriched 2w ago

Funding Stage

PUBLIC

Open Jobs

53-1 this month

Stable — net -1 jobs in 30d

23 added, 24 removed. Backfill posture.

Should You Work at HeartFlow?

AI assessment

Best fit for commercial, healthcare IT, and early-career professionals seeking growth-stage exposure; less ideal for drug development-focused scientists given diagnostic rather than therapeutic focus.

Why Work Here

Heavy commercial hiring (26 of 53 active roles) signals market expansion phase for established diagnostic platform
41% R&D intensity indicates sustained innovation investment in AI-powered coronary imaging analysis

Data completeness

5/9 — Partial

Company HealthStrong

Pipeline

Early-stage

23 total

LOE Risk

Protected

No near-term cliffs

Hiring

Stable

Revenue

$87M

Key Products

HeartFlow CT-FFR

Stable angina, coronary artery disease

Growth

Flagship AI-enabled coronary computed tomography FFR analysis product driving commercial expansion and clinical validation studies.

HeartFlow PCI Navigator

Coronary artery disease intervention planning

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Pipeline & Clinical Trials

Heartflow PCI Navigator

Coronary Artery Disease (CAD)

N/A

Clinical Trials (1)

NCT07479433The NAVIGATE-PCI Registry: A New Approach to VIew CT-derived Guidance Ahead of Stenting To Plan Efficient PCI

N/A

ICA

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT01757678HeartFlowNXT - HeartFlow Analysis of Coronary Blood Flow Using Coronary CT Angiography

N/A

FFRCT

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT05325112Assessing Diagnostic Value of Non-invasive FFR-CT (Fractional Flow Reserve - Computed Tomography) in Coronary Care in the Emergency Department

N/A

Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography a

Acute Coronary Syndrome

N/A

Clinical Trials (1)

NCT02374775Exploring the MEchanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and computationaL Fluid Dynamic

N/A

CMR and CTCA with CT-FFR

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT04761991CMR Versus CT in Coronary Artery Disease

N/A

HeartFLow CT-FFR

Angina, Stable Chest Pain

N/A

Clinical Trials (1)

NCT03026283The Value of CT Fractional Flow Reserve

N/A

Coronary Angiography

Coronary Artery Diseases

N/A

Clinical Trials (1)

NCT02813473SYNTAX III REVOLUTION Trial: A Randomized Study Investigating the Use of CT Scan and Angiography of the Heart to Help the Doctors Decide Which Method is the Best to Improve Blood Supply to the Heart in Patients With Complex Coronary Artery Disease

N/A

Coronary computed tomography angiography

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT04142021Safety and Feasibility Evaluation of Planning and Execution of Surgical Revascularization Solely Based on Coronary CTA and FFRCT in Patients With Complex Coronary Artery Disease (FASTTRACK CABG)

N/A

AI-enabled quantitative coronary plaque analysis

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT06376851AI DErived Plaque Quantification: CCTA and AI-QCPA for Determining Effective CAD Management

N/A

High intensity lipid lowering

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT05368545Influence of Lipid Lowering on Impaired Coronary Flow

N/A

The PLATFORM Study: Prospective LongitudinAl Trial of FFRct: Outcome and Resource IMpacts)

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT01943903The PLATFORM Study: Prospective LongitudinAl Trial of FFRct: Outcome and Resource IMpacts)

N/A

FFR

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT01233518Determination of Fractional Flow Reserve by Anatomic Computed Tomographic Angiography

N/A

Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT02499679Assessing Diagnostic Value of Non-invasive FFRCT in Coronary Care

N/A

cCTA with selective FFRct

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT03702244The PRECISE Protocol: Prospective Randomized Trial of the Optimal Evaluation of Cardiac Symptoms and Revascularization

N/A

Total Plaque Volume

Coronary Artery Disease (CAD) (E.G., Angina, Myocardial Infarction, and Atherosclerotic Heart Disease (ASHD))

N/A

Clinical Trials (1)

NCT05138289The REVEALPLAQUE Study: A pRospEctiVe, multicEnter Study to AnaLyze PLAQUE Using CCTA

N/A

Coronary computed tomography angiography

Coronary Artery Disease (CAD)

N/A

Clinical Trials (1)

NCT06831409Using CTA Measures to Define Cardiac Risk In NFL Alumni

N/A

CT Coronary Angiography

ST Elevation Myocardial Infarction

N/A

Clinical Trials (1)

NCT06506448Risk Characterization of Non-culprit Vessels in Patients Undergoing Primary PCI for ST-elevation MI in Multivessel Disease

N/A

DEFINing the PrEvalence and Characteristics of Coronary Artery Disease Among Patients With TYPE 2 My

Type 2 Myocardial Infarction

N/A

Clinical Trials (1)

NCT04864119DEFINing the PrEvalence and Characteristics of Coronary Artery Disease Among Patients With TYPE 2 Myocardial Infarction Using CT-FFR

N/A

data collection, non-intervention

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT03021382Comparisons of Morphological Measurement Between Coronary Computed Tomography and Optical Coherence Tomography

N/A

Rosuvastatin 40mg

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT06603363Changes in Plaque Characteristics After Short-term Statin Therapy as Assessed With Coronary CT

N/A

The COMPLETE Study

Coronary Artery Disease

N/A

Clinical Trials (1)

NCT06205810The COMPLETE Study

N/A

Evolocumab

Coronary Artery Disease

PHASE_4

Clinical Trials (1)

NCT03851263Multislice Computed Tomography Assessment of PCSK9 Inhibition on Coronary Perfusion

Phase 4

Multi-sliced computed tomography

Multivessel Coronary Artery Disease

PHASE_4

Clinical Trials (1)

NCT03851276A Multicentre, Pilot Study to Evaluate the Safety and the Feasibility of Planning and Execution of Surgical Revascularization in Patients With Complex Coronary Artery Disease, Based Solely on MSCT Imaging Utilizing GE Healthcare Revolution CT and HeartFlow FFRCT.

Phase 4

Interview Prep Quick Facts

Portfolio: 23 clinical trials

Top TAs: Cardiovascular

H-1B (2023): 1 approval

Publications: 25 in PubMed

SEC Filings: 1 available

Open Roles: 53 active jobs

Therapeutic Area Focus

Cardiovascular

20 pipeline

Marketed

Pipeline

Financials (FY2025)

Revenue

$87M

R&D Spend

$36M(41%)

Net Income

-$96M

Cash

$123M

Source: SEC 10-K Filing

Hiring Trend

Slowing Down

Open Roles

Added

-4

Filled/Removed

Based on last 4 crawl cycles

Visa Sponsorship

Sponsors Work Visas

H-1B Petitions (FY2023)

Approved

Denied

100%

Rate

Source: USCIS H-1B Employer Data Hub

Research Publications(10)

Recent peer-reviewed publications with author affiliations at this company

Artificial intelligence-enabled coronary plaque quantification for personalized risk assessment and lipid-lowering therapy: Insights from the FISH&CHIPS study(✰).

American journal of preventive cardiology

2026

PMID:42006406

Coronary Atherosclerosis in Former NFL Players: A Case Series From the GAMEFILM Registry.

HeartFlow(HTFL)

Should You Work at HeartFlow?

Why Work Here

Key Products

Watch Out For

Pipeline & Clinical Trials

Recent News · HeartFlow(2)

Open Jobs (53)

Staff Data Scientist

Marketing Communications Manager

Senior Software Engineer - Backend

Senior Data Engineer - AI Empowerment

Senior Software Engineer - Frontend

Senior Technical Project Manager

Senior Device Quality Engineer

Senior Manager, Device Quality Engineering

Solution Architect

Staff/Lead Site Reliability Engineer (SRE)

Territory Account Manager - Baltimore, MD / Washington DC

Territory Account Manager - Houston Medical Center

Territory Account Manager - Madison, WI

Territory Account Manager - Minneapolis, MN

Territory Account Manager - Morristown, NJ; Bridgewater, NJ

Regional Customer Success Director - Great Lakes

International Marketing Senior Manager

Implementation Manager - Great Lakes

District Sales Manager - UK Midlands

CT Applications Specialist – Heartflow EMEA

Clinical Trial Manager - West Coast

Clinical Trial Manager - San Francisco

Imaging Analyst

Clinical Trial Manager - East Coast

Principal Risk Quality Engineer

Financials (FY2025)

Hiring Trend

Visa Sponsorship

Research Publications(10)