ST Elevation Myocardial Infarction

Pipeline Programs

Companies

Clinical Trials

4 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

14 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Boston ScientificCA - Valencia

3 programs

ColchicinePhase 31 trial

CT Coronary AngiographyN/A

Percutaneous coronary interventionN/A1 trial

Active Trials

NCT05604976Unknown430Est. Dec 2025

NCT03048825Completed7,264Est. Aug 2024

AstraZenecaCAMBRIDGE, United Kingdom

2 programs

Ticagrelor orodispersible tabletsPhase 31 trial

TicagrelorPhase 21 trial

Active Trials

NCT03145194Unknown140Est. Nov 2019

NCT03822377Completed130Est. Aug 2020

Medica CorpMA - Bedford

1 program

DLBS1033Phase 2/31 trial

Active Trials

NCT02976701Terminated23Est. Mar 2023

Dexa MedicaIndonesia - Tangerang

1 program

DLBS1033Phase 2/3

BiocorpFrance - Issoire

2 programs

Allogeneic umbilical cord mesenchymal stem cellsPhase 21 trial

NP202Phase 21 trial

Active Trials

NCT06147986Recruiting41Est. Jun 2027

NCT02557217Unknown120Est. Feb 2018

ResoTher PharmaDenmark - Holte

1 program

RTP-026Phase 21 trial

Active Trials

NCT06465303Recruiting96Est. Dec 2025

AbbottABBOTT PARK, IL

2 programs

Continuous Saline ThermodilutionN/A1 trial

angiographyN/A1 trial

Active Trials

NCT06795035Recruiting70Est. Dec 2027

NCT04996277Unknown300Est. Mar 2024

InspireMDIsrael - Tel Aviv

2 programs

MGuard PrimeN/A1 trial

MGuard™ Prime Embolic Protection Stent SystemN/A1 trial

Active Trials

NCT01869738Terminated310Est. Aug 2015

NCT02292823Terminated63Est. Sep 2016

HeartFlowSAN FRANCISCO, CA

1 program

CT Coronary AngiographyN/A1 trial

Active Trials

NCT06506448Recruiting320Est. Jan 2029

Pulse BiosciencesCA - Hayward

1 program

PCIN/A1 trial

Active Trials

NCT04259853UnknownEst. Feb 2026

Miracor MedicalBelgium - Awans

1 program

PICSON/A1 trial

Active Trials

NCT03473015Completed105Est. Oct 2020

MicroPortChina - Shanghai

1 program

Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular N/A

Acist Medical SystemsMN - Eden Prairie

1 program

Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular N/A1 trial

Active Trials

NCT05007535Unknown200Est. Feb 2023

PEEL TherapeuticsUT - Salt Lake City

1 program

autoRICN/A1 trial

Active Trials

NCT03265067CompletedEst. Jul 2019

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

2029

AstraZenecaTicagrelor orodispersible tablets

Boston ScientificColchicine

Medica CorpDLBS1033

ResoTher PharmaRTP-026

BiocorpAllogeneic umbilical cord mesenchymal stem cells

AstraZenecaTicagrelor

BiocorpNP202

AbbottContinuous Saline Thermodilution

HeartFlowCT Coronary Angiography

Boston ScientificPercutaneous coronary intervention

Abbottangiography

Acist Medical SystemsTissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular

Pulse BiosciencesPCI

PEEL TherapeuticsautoRIC

Miracor MedicalPICSO

Showing 15 of 17 trials with date data

Clinical Trials (17)

Total enrollment: 9,612 patients across 17 trials

NCT03822377 AstraZenecaTicagrelor orodispersible tablets

Ticagrelor Administered as Standard Tablet or Orodispersible Formulation

Start: Jun 2019Est. completion: Aug 2020130 patients

Phase 3Completed

NCT03048825 Boston ScientificColchicine

Colchicine and Spironolactone in Patients with MI / SYNERGY Stent Registry

Start: Feb 2018Est. completion: Aug 20247,264 patients

Phase 3Completed

NCT02976701 Medica CorpDLBS1033

Effect of DLBS1033 After Primary PCI in Patients With STE-ACS

Start: Nov 2016Est. completion: Mar 202323 patients

Phase 2/3Terminated

NCT06465303 ResoTher PharmaRTP-026

A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)

Start: Jul 2024Est. completion: Dec 202596 patients

Phase 2Recruiting

NCT06147986 BiocorpAllogeneic umbilical cord mesenchymal stem cells

Evaluate the Efficacy and Safety of Allogeneic Umbilical Cord Mesenchymal Stem Cells As an Add-On Treatment for Acute ST-elevation Myocardial Infarction (STEMI) Patients

Start: Sep 2023Est. completion: Jun 202741 patients

Phase 2Recruiting

NCT03145194 AstraZenecaTicagrelor

TIMES: Ticagrelor vs. Placebo/ Clopidogrel With Aspirin in Anterior STEMI Patients Treated With Primary PCI

Start: Jan 2017Est. completion: Nov 2019140 patients

Phase 2Unknown

NCT02557217 BiocorpNP202

NP202 for Treatment of Post -STEMI Left Ventricular Systolic Dysfunction

Start: Oct 2015Est. completion: Feb 2018120 patients

Phase 2Unknown

NCT06795035 AbbottContinuous Saline Thermodilution

Assessment of Coronary Microvascular Dysfunction After STEMI Using Continuous Saline Thermodilution

Start: May 2025Est. completion: Dec 202770 patients

N/ARecruiting

NCT06506448 HeartFlowCT Coronary Angiography

Risk Characterization of Non-culprit Vessels in Patients Undergoing Primary PCI for ST-elevation MI in Multivessel Disease

Start: Jan 2025Est. completion: Jan 2029320 patients

N/ARecruiting

NCT05604976 Boston ScientificPercutaneous coronary intervention

Single Catheter Primary Percutaneous Coronary Intervention Method in Patients With ST Elevation Myocardial Infarction

Start: Nov 2022Est. completion: Dec 2025430 patients

N/AUnknown

NCT04996277 Abbottangiography

A Prospective Evaluation of Clinical Impact of Physiology Versus Optical Coherence Tomography Guided PCI in STEMI Patients Without Undergoing Primary PCI

Start: Jul 2021Est. completion: Mar 2024300 patients

N/AUnknown

NCT05007535 Acist Medical SystemsTissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular

Tissue Characterization and Primary Percutaneous Coronary Intervention Guidance Using Intravascular Ultrasound

Start: Nov 2020Est. completion: Feb 2023200 patients

N/AUnknown

NCT04259853 Pulse BiosciencesPCI

Quantitative Fractional Ratio-guided Revascularization in STEMI Patients With Multi-vessel Disease

Start: Jan 2020Est. completion: Feb 2026

N/AUnknown

NCT03265067 PEEL TherapeuticsautoRIC

Field Implementation of the autoRIC Device in STEMI

Start: Jul 2016Est. completion: Jul 2019

N/ACompleted

NCT03473015 Miracor MedicalPICSO

Oxford Acute Myocardial Infarction - Pressure-controlled Intermittent Coronary Sinus Occlusion

Start: Jul 2015Est. completion: Oct 2020105 patients

N/ACompleted

NCT02292823 InspireMDMGuard™ Prime Embolic Protection Stent System

MGuard™ Prime Embolic Protection Stent in Patients With Acute ST Elevation Myocardial Infarction

Start: Apr 2014Est. completion: Sep 201663 patients

N/ATerminated

NCT01869738 InspireMDMGuard Prime

MGuard™ Prime Stent System Clinical Trial in Patients With Acute ST Elevation Myocardial Infarction

Start: Jun 2013Est. completion: Aug 2015310 patients

N/ATerminated

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

2 late-stage (Phase 3) programs, potential near-term approvals

4 actively recruiting trials targeting 9,612 patients

14 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.