PEMETREXED DISODIUM (pemetrexed) by Viatris (2) is folate-dependent metabolic processes essential for cell replication. Approved for non-small cell lung cancer, non-small cell lung cancer [see ], lung cancer and 1 more indications. First approved in 2022.
Drug data last refreshed 20h ago
folate-dependent metabolic processes essential for cell replication. In vitro studies show that pemetrexed inhibits thymidylate synthase (TS), dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase (GARFT), which are folate-dependent enzymes involved in the de novo biosynthesis…
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