FYCOMPA

LOE Approaching

perampanel

NDAORALSUSPENSION
Approved
Apr 2016
Lifecycle
LOE Approaching
Competitive Pressure
25/100
Clinical Trials
20

Mechanism of Action

AMPA Receptor Antagonists

Pharmacologic Class:

Noncompetitive AMPA Glutamate Receptor Antagonist

Clinical Trials (5)

NCT06657378N/ARecruiting

A Study to Evaluate the Safety of Fycompa Injection in Participants With Partial-Onset Seizures or Primary Generalized Tonic- Clonic Seizures

Started Nov 2024
110 enrolled
Partial-Onset SeizuresPrimary Generalized Tonic-clonic Seizures
NCT05533814Phase 4Completed

A Study to Evaluate the Efficacy and Safety of Perampanel Monotherapy in Untreated Participants With Focal Onset Seizures With or Without Focal to Bilateral Tonic-clonic Seizures

Started Oct 2022
125 enrolled
Epilepsy
NCT05201703Phase 4Terminated

Fycompa in Catamenial Epilepsy

Started Mar 2022
7 enrolled
Catamenial Epilepsy
NCT04417907Phase 4Terminated

Perampanel Titration and Cognitive Effects

Started Oct 2021
29 enrolled
Epilepsy
NCT04497142Phase 1/2Completed

Effect of Perampanel on Peritumoral Hyperexcitability in HGG

Started Nov 2020
12 enrolled
Glioma, MalignantSurgerySeizures

Loss of Exclusivity

LOE Date
Jul 1, 2026
4 months away
Patent Expiry
Jul 1, 2026

Patent Records (1)

Patent #ExpiryTypeUse Code
8772497
Jul 1, 2026
Substance