NDAORALTABLET, EXTENDED RELEASE
Approved
Nov 2011
Lifecycle
LOE Approaching
Competitive Pressure
15/100
Clinical Trials
4
Data completeness
7/8 — Comprehensive
FORFIVO XL (bupropion hydrochloride) by Lavipharm is unknown, as is the case with other antidepressants. Approved for major depressive disorder, smoking cessation. First approved in 2011.
Drug data last refreshed 18h ago · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
FORFIVO XL is an extended-release oral tablet formulation of bupropion hydrochloride, a noradrenergic and dopaminergic antidepressant with unknown exact mechanism of action. It treats major depressive disorder, smoking cessation, seasonal affective disorder, attention deficit disorder, and is being studied in lung cancer. The drug works as a weak inhibitor of neuronal norepinephrine and dopamine reuptake, distinguishing it from serotonergic antidepressants.
$0.414MPart D
LOE Approaching2.3 years to LOEDeclining market trajectory with 2.4 years to LOE signals accelerated focus on generic transition support and managed care contracting; brand team will contract significantly post-2028.
Mechanism of Action
unknown, as is the case with other antidepressants. However, it is presumed that this action is mediated by noradrenergic and/or dopaminergic mechanisms. Bupropion is a relatively weak inhibitor of the neuronal uptake of norepinephrine and dopamine, and does not inhibit monoamine oxidase or the…
Indications (2)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.