Smoking Cessation
Pipeline by Development Stage
Drug Modality Breakdown
On Market (1)
Approved therapies currently available
Competitive Landscape
31 companies ranked by most advanced pipeline stage
+1 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 19,107 patients across 50 trials
Varenicline Augmentation of Patch Outcomes in Heavy Drinkers' Smoking Cessation
Smoking Cessation Study In Healthy Adolescent Smokers
A Multi-National Study To Assess How Effective And Safe The Smoking Cessation Medicine Varenicline Is In Smokers Who Have Already Tried Varenicline In The Past As A Prescription Medicine From Their Usual Healthcare Provider
Safety And Efficacy Of 12 Weeks Of Varenicline For Smoking Cessation In Smokers With Depression
Varenicline Treatment for Smoking Cessation in Patients With Bipolar Disorder
A Pilot Study Of Smoking Cessation Treatment Including Varenicline In Patients Scheduled For Planned Surgery
Impact Of Smoking Cessation Treatment Reimbursement On The Quit Rates In Smokers Motivated To Quit
Assessing Neuropsychiatric Symptoms Including Depression, Anxiety, Irritability, and Suicidal Thoughts or Behavior in Subjects Quitting Smoking on Varenicline Tartrate or Placebo
Assessment of Safety and Efficacy of Varenicline in Patients That Wish to Stop Smoking
Message Priming and Enrollment in, and Response to, a Smoking Cessation Program: A Pilot Study
Phase 3 Trial Evaluating the Efficacy and Safety of Cytisinicline for Vaping Cessation in Adults Using Nicotine-Containing E Cigarettes
Safety Study of Cytisinicline in Adult Combustible and/or E-cigarette Smokers
A Second Study of Cytisinicline for Smoking Cessation in Adult Smokers
A Study of Cytisinicline for Smoking Cessation in Adult Smokers
Evaluation of Deep Transcranial Magnetic Stimulation (DTMS) With the H-ADD Coil as an Aid to Smoking Cessation.
Nicotine Mouth Film for Craving Relief.
Combining Varenicline and Bupropion for Smoking Cessation
Disease Management for Smoking Cessation
Efficacy and Safety of Dianicline Treatment as an Aid to Smoking Cessation in Cigarette Smokers (AMERIDIAN)
An Investigation of Effectiveness and Safety of Varenicline Tartrate in Helping People Quit Smoking
A Twelve-Week Study of Varenicline for Safety and Efficacy in Comparison With Placebo for Smoking Cessation
An Open Label Study That Compares Varenicline to Transdermal Nicotine Patch for Smoking Cessation
A 52-Week Placebo-Controlled Study Evaluating the Safety of Varenicline
A Twelve-Week Study of Varenicline for Safety and Efficacy in Comparison With Placebo and Zyban for Smoking Cessation
A 52-Week Multicenter Study Evaluating the Safety and Efficacy of Varenicline for the Maintenance of Smoking Cessation
Comparison of the Efficacy and Safety of 2 Oral Doses of Rimonabant, 5 mg/Day or 20 mg/Day, Versus Placebo, as an Aid to Smoking Cessation (STRATUS US)
Smoking Reduction or Cessation With Nicotine Replacement Therapy
Evaluating Smoking Cessation Interventions for PWH in South Africa
Smoking Cessation & Opioid Dependence Treatment Integration
Examining the Effects of Cytisinicline on Neural Substrates of Cigarette Cue-reactivity
Study Assessing Efficacy and Safety of NFL-101 on Reduction of Reinforcing Properties of Cigarettes (PRECESTO)
A Study of Cytisinicline for Vaping Cessation in Adult Smokers
Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment
High Dose Bupropion for Smoking Cessation - Pilot Study
Study Assessing Efficacy and Safety of NFL-101 as a Tobacco Cessation Therapy
Effectiveness of Combination Varenicline and Oral Nicotine Replacement Therapy (COMBO)
Daily Liraglutide for Nicotine Dependence
Trial of Cytisine in Adult Smokers
AXS-05 Phase II Trial on Smoking Behavior
Efficacy of 2 Probiotics During Nicotine Replacement Therapy on Withdrawal Symptoms Associated With Smoking Cessation
Efficacy and Safety of Βeta-adrenoceptor Inverse Agonist and Biased Ligand, Nadolol, In Smoking Cessation of Patients With Chronic Cough With or Without Airflow Obstruction
Pharmacokinetic Study of 4 mg Nicotine Lozenge.
Provoked Craving Relief Study by NRT
Randomized Trial to Evaluate the Effectiveness of X-22 as a Smoking Cessation Aid
A Study to Evaluate the Safety and Efficacy of Three Doses of a Controlled Release Formulation of Varenicline for Smoking Cessation
An Alternative Dosing Schedule of Varenicline for Smoking Cessation
Pilot Study of a New Nicotine Replacement Therapy
12 Week Evaluation of the Safety and Efficacy of 3 Doses of CP-526,555 and Placebo for Smoking Cessation
12 Week Evaluation of the Safety and Efficacy of a Flexible Dose of CP-526,555 and Placebo for Smoking Cessation
12 Week Evaluation of the Safety and Efficacy of 4 Dosing Strategies of CP-526,555 and Placebo for Smoking Cessation.
Phase Legend
Key Insights
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.