Major Depressive Disorder
Pipeline by Development Stage
Drug Modality Breakdown
On Market (17)
Approved therapies currently available
Competitive Landscape
90 companies ranked by most advanced pipeline stage
+60 more companies
Trial Timeline
Clinical trial activity over time
Showing 15 of 50 trials with date data
Clinical Trials (50)
Total enrollment: 9,876 patients across 50 trials
To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets
A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms
Brexpiprazole as Adjunctive Therapy in Adults With Major Depressive Disorder
Leveraging EEG for Antidepressant Prediction With Sertraline and Escitalopram
Leveraging EEG for Antidepressant Prediction With Duloxetine and Bupropion
Comparison of Vortioxetine and Desvenlafaxine in Adult Patients Suffering From Depression
Vortioxetine in Patients With Depression and Early Dementia
Open-label, Flexible-dose Study of Vortioxetine in Patients With Depression in India
Vortioxetine Monotherapy for Major Depressive Disorder in Type 2 Diabetes
Study With Vortioxetine on Emotional Functioning in Patients With Depression
Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment
Brainsway DTMS for Treatment of MDD Using iTBS
Pattern Separation, Brain Derived Neurotrophic Factors, and Mechanisms of Vortioxetine
Goal Achievement After a Change to Vortioxetine in Adults With Major Depressive Disorder
The Relationship Among Changes in Brain Network Activation in Adult Outpatients With Major Depressive Disorder
Remediation of Age-related Cognitive Decline: Vortioxetine and Cognitive Training
Vortioxetine for MDD, Cognition, and Systemic Inflammatory Biomarkers
Trial of Levomilnacipran in Geriatric Depression
Vortioxetine for Menopausal Depression
Vortioxetine, 5, 10, and 20 mg, Relapse Prevention Study in Adults With Major Depressive Disorder (MDD)
Assessment in Work Productivity and the Relationship With Cognitive Symptoms in Patients With MDD Taking Vortioxetine
Desvenlafaxine in Opioid-Dependent Patients
Vilazodone for Treatment of Geriatric Depression
Lexapro®'s Efficacy After Dose Escalation in Remission Study
Aripiprazole (Abilify®) as an Adjunctive Treatment for Inadequate Response in Major Depressive Disorder
Effect of Antidepressants on White Matter Structure
Aripiprazole for the Augmentation of Antidepressant Therapy
12-Week Study of Pristiq (Desvenlafaxine) Social Anxiety Disorder
Biomarkers of Antidepressant Treatment in Adolescents With Major Depression (The Adolescents MDD Study)
A Study of the Neurobiology of Depression
Biomarkers for Outcomes In Late-life Depression (BOLD)
A Study of Patients With Major Depressive Disorder and Residual Apathy
Study Evaluating Effexor XR in Chinese Subjects With Major Depressive Disorder
Neuroimaging Study of Bupropion Treatment in Patients With Major Depressive Disorder
Quantitative Electroencephalogram (QEEG) Predictors of Response to Psychotherapy Versus Antidepressant Treatment in Depression
Brain Mechanisms and Targeting Insomnia in Major Depression
Duloxetine Treatment of Major Depression and Chronic Low Back Pain For Older Adults
Study Comparing the Efficacy of Venlafaxine XR Vs. SSRIs and Conventional Antidepressants in Depressed Patients
Acamprosate Added to Escitalopram and Behavioral Treatment for Comorbid Depression and Alcoholism
A Study Evaluating Duloxetine in Patients Hospitalized for Severe Depression
Escitalopram and Sleep Architecture in Patients With Major Depressive Disorder
A Study Comparing the Efficacy and Safety of Duloxetine and Placebo for the Treatment of Depression in Elderly Patients
Efficacy and Tolerability of Escitalopram and Duloxetine in Outpatients With Major Depressive Disorder
Treatment of Nicotine Dependence and Acute Depression
Quantitative EEG (QEEG) as a Predictor of Treatment Outcome in Depression
Electroencephalography (EEG) Biomarkers of Response in Depression
Major Depressive Disorder Study In Adults
Neurophysiologic Monitoring of Antidepressant Treatment
Study Evaluating DVS-233 SR and Venlafaxine ER in Adult Outpatients With Major Depressive Disorder
Study Evaluating DVS-233 SR And Venlafaxine ER In Adult Outpatients With Major Depressive Disorder
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