EPZICOM

Pre-Launch

abacavir; lamivudine

Viatris (2)

ANDAORALTABLET

Lifecycle

Pre-Launch

Clinical Trials

Data completeness

4/8 — Partial

EPZICOM (abacavir; lamivudine) by Viatris (2) is mechanism of action: abacavir is a carbocyclic synthetic nucleoside analogue. Approved for hiv-1 infection.

Drug data last refreshed 1mo ago

$0.0BPart D

Mechanism of Action

Mechanism of Action: Abacavir is a carbocyclic synthetic nucleoside analogue. Abacavir is converted by cellular enzymes to the active metabolite, carbovir triphosphate (CBV-TP), an analogue of deoxyguanosine-5′-triphosphate (dGTP). CBV-TP inhibits the activity of HIV-1 reverse transcriptase (RT)…

Indications (1)

HIV-1 infection

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Data Sources

Drug label: DailyMed / FDA
Clinical trials: ClinicalTrials.gov
Patent data: FDA Orange Book
Spending data: CMS Medicare

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.

Clinical Trials (5)

NCT02626923N/ACompleted

Study of Maraviroc (MVC) and Epzicom (ABC/3TC) Once-Daily in ART-Naive & First Switch Patients

Started Jul 2012

51 enrolled

Drug-induced Hypotension

NCT01102972Phase 4Completed

A Simplification Study of Unboosted Reyataz With Epzicom (ASSURE)

Started Apr 2010

297 enrolled

Infection, Human Immunodeficiency Virus

NCT00724711Phase 4Completed

Safety and Efficacy Study of Switching From Epzicom to Truvada

Started Jul 2008

312 enrolled

HIV Infection

NCT00740064Phase 4Unknown

Pilot Study With Isentress (Raltegravir) and Epzicom (Abacavir/Lamivudine) in Treatment Naive HIV-Infected Subjects

Started May 2008

30 enrolled

HIV Infections

NCT00337922Phase 4Completed

Pharmacokinetic Study Of EPZICOM Tablet

Started Jul 2006

8 enrolled

HIV Infection