NDAORALCAPSULE, EXTENDED RELEASE
Approved
Oct 1997
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
12
Data completeness
6/8 — Strong
EFFEXOR XR (venlafaxine hydrochloride) by Viatris (2) is mdd, gad, sad, and pd is unclear, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake. Approved for major depressive disorder, generalized anxiety disorder. First approved in 1997.
Drug data last refreshed Yesterday · AI intelligence enriched 3w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
EFFEXOR XR (venlafaxine hydrochloride) is an extended-release oral capsule approved in October 1997 for the treatment of anxiety, depression, generalized anxiety disorder, social anxiety disorder, and panic disorder. The drug works by inhibiting the reuptake of serotonin and norepinephrine in the central nervous system, enhancing their activity. It represents a serotonin-norepinephrine reuptake inhibitor (SNRI) class medication and serves as a foundational treatment option in the psychiatric therapeutic landscape.
$0.0BPart D
Mechanism of Action
MDD, GAD, SAD, and PD is unclear, but is thought to be related to the potentiation of serotonin and norepinephrine in the central nervous system, through inhibition of their reuptake.
Indications (2)
Clinical Trials (12)
To Evaluate the Long-term Efficacy and Safety of Toludevenlafaxine Hydrochloride Sustained-release Tablets
Started May 2024
736 enrolled
Major Depressive Disorder
A Study to Evaluate Efficacy and Safety of Toludesvenlafaxine Hydrochloride Sustained-release Tablets in Generalized Anxiety Disorder.
Started Jul 2023
555 enrolled
Generalized Anxiety Disorder
A Study to Assess The Effects Of Effexor XR On Cardiac Repolarization In Healthy Adult Subjects
Started Dec 2015
54 enrolled
Healthy Subjects
Co-Administration of LDX (SPD489) and Venlafaxine XR (EFFEXOR XR) in Healthy Volunteers
Started Oct 2010
80 enrolled
Healthy
Study Evaluating Effexor XR in Chinese Subjects With Major Depressive Disorder
Started Apr 2009
0Major Depressive Disorder
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.