NDAINJECTIONINJECTABLE
Approved
May 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
3
Data completeness
6/8 — Strong
Drug Shortage Active
DEPO-MEDROL is currently in shortage. Reason: Available. This may impact manufacturing, supply chain, and quality hiring at the manufacturer.
DEPO-MEDROL (methylprednisolone acetate) by Pfizer is clinical pharmacology glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids. Approved for dermatomyositis, polymyositis, systemic lupus erythematosus and 13 more indications. First approved in 1959.
Drug data last refreshed Yesterday · AI intelligence enriched 2w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DEPO-MEDROL (methylprednisolone acetate) is a synthetic glucocorticoid administered via injection that suppresses inflammation and modifies immune response across multiple organ systems. It treats autoimmune and inflammatory conditions including rheumatoid arthritis, lupus, ulcerative colitis, asthma, and allergic reactions by inhibiting pro-inflammatory mediators and immune cell activation.
$21KPart D
LOE ApproachingDeclining
Product is in late-stage maturity with minimal Part D penetration; commercial teams should focus on niche indications and specialist segments rather than volume growth.
Mechanism of Action
CLINICAL PHARMACOLOGY Glucocorticoids, naturally occurring and synthetic, are adrenocortical steroids. Naturally occurring glucocorticoids (hydrocortisone and cortisone), which also have salt retaining properties, are used in replacement therapy in adrenocortical deficiency states. Their synthetic…
Indications (16)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.