DECADRON W/ XYLOCAINE
LOE Approachingdexamethasone sodium phosphate; lidocaine hydrochloride
NDAINJECTIONINJECTABLE
Approved
Jul 1962
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Data completeness
2/8 — Basic
DECADRON W/ XYLOCAINE (dexamethasone sodium phosphate; lidocaine hydrochloride) by Merck & Co.. Approved for rheumatoid arthritis, rheumatoid arthritis, psoriasis and 10 more indications. First approved in 1962.
Drug data last refreshed 15h ago · AI intelligence enriched 3d ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DECADRON W/ XYLOCAINE is a fixed-dose combination injectable containing dexamethasone sodium phosphate (corticosteroid) and lidocaine hydrochloride (local anesthetic). It is indicated for inflammatory and autoimmune conditions including rheumatoid arthritis, psoriasis, asthma, atopic dermatitis, ulcerative colitis, multiple sclerosis, and hematologic malignancies. The corticosteroid suppresses immune response and inflammation while lidocaine provides local anesthesia at the injection site.
LOE Approaching
As an aging NDA approaching loss of exclusivity with moderate competitive pressure (30%), the brand team likely focuses on cost management and defending market share against generic entrants rather than growth initiatives.
Mechanism of Action
Mechanism of action data is being enriched from DailyMed and FDA sources. Check back soon for updated drug intelligence.
Indications (11)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.