NDAOPHTHALMICOINTMENT
Approved
Sep 1959
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4
Data completeness
4/8 — Partial
DECADRON (dexamethasone sodium phosphate) by Merck & Co. is clinical pharmacology naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Approved for ataxia telangiectasia, peripheral arterial disease, chronic limb ischemia and 3 more indications. First approved in 1959.
Drug data last refreshed 23h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
DECADRON (dexamethasone sodium phosphate) is a synthetic glucocorticoid used for its potent anti-inflammatory effects across multiple organ systems. It works by modifying immune responses and metabolic effects while lacking the sodium-retaining properties of natural glucocorticoids. The ophthalmic ointment formulation treats conditions including atopic keratoconjunctivitis and perioperative inflammation.
LOE Approaching
As a legacy product approaching loss of exclusivity with moderate competitive pressure (30/100), teams are likely focused on brand defense and cost management rather than expansion.
Mechanism of Action
CLINICAL PHARMACOLOGY Naturally occurring glucocorticoids, (hydrocortisone and cortisone), which also have salt-retaining properties, are used as replacement therapy in adrenocortical deficiency states. Their synthetic analogs, including dexamethasone, are primarily used for their potent…
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.