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Surgery

6
Pipeline Programs
30
Companies
33
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
0
4
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Small Molecule
1100%
+ 41 programs with unclassified modality

Competitive Landscape

27 companies ranked by most advanced pipeline stage

Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
3 programs
1
1
Haider ETT Tube Holder and Bite GuardPhase 41 trial
Adductor Canal Block + Catheter & IPACK blockPhase 11 trial
The Pediatric Anesthesia Quality Improvement ProjectN/A
Active Trials
NCT03774966Completed60Est. May 2019
NCT02347488Completed30Est. Jan 2016
Medtronic
MedtronicNJ - Phillipsburg
2 programs
1
atenololPhase 4Small Molecule1 trial
Enhanced Vitals MonitoringN/A
Active Trials
NCT00202358Unknown60Est. Sep 2008
Bactiguard
BactiguardSweden - Tullinge
1 program
1
BIP CVCPhase 41 trial
Active Trials
NCT02811380Completed36Est. Jan 2015
Next Science
Next ScienceAustralia - Sydney
1 program
1
Povidone-IodinePhase 41 trial
Active Trials
NCT05919888Completed60Est. Nov 2023
AstraZeneca
AstraZenecaCAMBRIDGE, United Kingdom
1 program
1
andexanet alfaPhase 21 trial
Active Trials
NCT04233073Terminated10Est. Jan 2022
Masimo
MasimoIRVINE, CA
8 programs
Blinded continuous vital sign monitoringN/A1 trial
DCI pulse oximeter sensorN/A1 trial
In vivo SpHb and PVi MonitoringN/A1 trial
Masimo Pulse CO-OximeterN/A1 trial
O3 regional oximeter sensorN/A1 trial
+3 more programs
Active Trials
NCT06232876Not Yet Recruiting522Est. Nov 2026
NCT03124901Completed147Est. Oct 2008
NCT02986789Terminated43Est. Aug 2018
+5 more trials
Medasense Biometrics
Medasense BiometricsIsrael - Ramat Gan
3 programs
Base level of remifentanil effect side concentration: 2ng/mlN/A1 trial
Clinical Evaluation of Medasense Pain Monitor PerformancesN/A1 trial
PMD-200N/A1 trial
Active Trials
NCT01762332Completed82Est. May 2014
NCT01631695Completed96Est. May 2012
NCT03276260Terminated2Est. Apr 2019
Oregon Therapeutics
3 programs
Oculus Quest: TRIPPN/A1 trial
SmartphoneN/A1 trial
Virtual RealityN/A1 trial
Active Trials
NCT04828980Completed32Est. Aug 2022
NCT04464304Completed30Est. Oct 2021
NCT04828109Completed80Est. Sep 2022
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
2 programs
Telehealth follow-upN/A1 trial
The Pediatric Anesthesia Quality Improvement ProjectN/A1 trial
Active Trials
NCT06210204Not Yet Recruiting3,000Est. Jul 2027
NCT00674388Recruiting5,000,000Est. Dec 2040
Nielsen BioSciences
Nielsen BioSciencesCA - San Diego
1 program
Bypass PACU in Knee and Hip ArthroplastyN/A1 trial
Active Trials
NCT03984942Completed600Est. Nov 2020
Apollo Therapeutics
Apollo TherapeuticsUK - Cambridge
1 program
Endoscopic Suturing (ES) RegistryN/A1 trial
Active Trials
NCT03776188Completed204Est. Nov 2021
Providence Therapeutics
1 program
Enhanced Vitals MonitoringN/A1 trial
Active Trials
NCT06584825Recruiting110Est. Dec 2027
Human BioSciences
Human BioSciencesWV - Martinsburg
1 program
In-home drug disposal pouchN/A1 trial
Active Trials
NCT05991687Recruiting100Est. Aug 2026
Solventum
SolventumMN - St. Paul
1 program
New PIV DressingN/A1 trial
Active Trials
NCT02725788Terminated247Est. May 2015
Asensus Surgical
Asensus SurgicalNC - Durham
1 program
Robotic Surgical SystemN/A
Nordic Pharma
Nordic PharmaFrance - Paris
1 program
Robotic-Arm Assisted THAN/A1 trial
Active Trials
NCT03891199Completed40Est. Aug 2020
Stryker
StrykerCA - San Jose
1 program
Robotic-Arm Assisted THAN/A
Fresenius Kabi
Fresenius KabiGermany - Bad Homburg
1 program
Safety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical PatientsN/A1 trial
Active Trials
NCT01820949Completed110,000Est. Sep 2015
CSL Behring
CSL BehringIL - Bradley
1 program
Safety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical PatientsN/A
B. Braun
B. BraunGermany - Melsungen
1 program
Safety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical PatientsN/A
CSL Seqirus
CSL SeqirusUK - Maidenhead
1 program
Safety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical PatientsN/A
Alcon
AlconFORT WORTH, TX
1 program
Surgical video gradingN/A1 trial
Active Trials
NCT06964139Completed5Est. Jul 2025
Haemonetics
HaemoneticsMA - Boston
1 program
TEG 6s Citrated K, KH, RTH, FFH CartridgeN/A1 trial
Active Trials
NCT06352125Completed338Est. Jan 2023
Cardinal Health
Cardinal HealthDUBLIN, OH
1 program
The Pediatric Anesthesia Quality Improvement ProjectN/A
Cook Medical
Cook MedicalIN - Bloomington
1 program
The Pediatric Anesthesia Quality Improvement ProjectN/A
Standard Bariatrics
Standard BariatricsNC - Morrisville
1 program
Titan SGS staplerN/A1 trial
Active Trials
NCT04347837Completed62Est. Dec 2020
Integra LifeSciences
Integra LifeSciencesAustralia - Clayton
1 program
craniectomyN/A1 trial
Active Trials
NCT01824706Completed110Est. May 2016

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
2030
2031
Next SciencePovidone-Iodine
Angeles TherapeuticsHaider ETT Tube Holder and Bite Guard
BactiguardBIP CVC
Medtronicatenolol
AstraZenecaandexanet alfa
Angeles TherapeuticsAdductor Canal Block + Catheter & IPACK block
Providence TherapeuticsEnhanced Vitals Monitoring
MasimoBlinded continuous vital sign monitoring
Colorado TherapeuticsTelehealth follow-up
AlconSurgical video grading
Human BioSciencesIn-home drug disposal pouch
HaemoneticsTEG 6s Citrated K, KH, RTH, FFH Cartridge
Oregon TherapeuticsVirtual Reality
Oregon TherapeuticsOculus Quest: TRIPP
Oregon TherapeuticsSmartphone

Showing 15 of 33 trials with date data

Clinical Trials (33)

Total enrollment: 5,116,477 patients across 33 trials

NCT05919888Next SciencePovidone-Iodine

SURGX Antimicrobial Gel Versus Povidone-iodine Skin Incision Prep in Total Shoulder Arthroplasty

Start: Jun 2023Est. completion: Nov 202360 patients
Phase 4Completed
NCT02347488Angeles TherapeuticsHaider ETT Tube Holder and Bite Guard

Endotracheal Tube Holder and Bite Guard Research

Start: Feb 2015Est. completion: Jan 201630 patients
Phase 4Completed
NCT02811380BactiguardBIP CVC

BIP CVC Clinical Safety and Performance Study

Start: Sep 2013Est. completion: Jan 201536 patients
Phase 4Completed
NCT00202358Medtronicatenolol

Perioperative Effect of Atenolol on Cytokine Profiles

Start: Nov 2002Est. completion: Sep 200860 patients
Phase 4Unknown
NCT04233073AstraZenecaandexanet alfa

Trial of Andexanet in Patients Receiving an Oral FXa Inhibitor Who Require Urgent Surgery

Start: Jun 2021Est. completion: Jan 202210 patients
Phase 2Terminated
NCT03774966Angeles TherapeuticsAdductor Canal Block + Catheter & IPACK block

IPACK and Adductor Canal Catheter Patient Outcomes for TKAs?

Start: Feb 2019Est. completion: May 201960 patients
Phase 1Completed
NCT06584825Providence TherapeuticsEnhanced Vitals Monitoring

Enhanced Vitals Monitoring After Major Surgery Trial

Start: Nov 2025Est. completion: Dec 2027110 patients
N/ARecruiting
NCT06232876MasimoBlinded continuous vital sign monitoring

Continuous Versus Intermittent Ward Monitoring

Start: Nov 2025Est. completion: Nov 2026522 patients
N/ANot Yet Recruiting
NCT06210204Colorado TherapeuticsTelehealth follow-up

Improving Access to Surgical Care: Safety, Efficacy, and Satisfaction With Postoperative Telehealth

Start: Jan 2025Est. completion: Jul 20273,000 patients
N/ANot Yet Recruiting
NCT06964139AlconSurgical video grading

Hydrus Learning Curve Study

Start: Dec 2024Est. completion: Jul 20255 patients
N/ACompleted
NCT05991687Human BioSciencesIn-home drug disposal pouch

Methods for Effective Disposal of Surplus Analgesics to Facilitate Elimination

Start: Jul 2023Est. completion: Aug 2026100 patients
N/ARecruiting
NCT06352125HaemoneticsTEG 6s Citrated K, KH, RTH, FFH Cartridge

An Observational Trial to Assess the Performance of the TEG® 6s Diagnostic System With the Citrated K, KH, RTH, FFH Cartridge

Start: Dec 2021Est. completion: Jan 2023338 patients
N/ACompleted
NCT04828109Oregon TherapeuticsVirtual Reality

Digital Intervention Postoperative Protocol

Start: Oct 2021Est. completion: Sep 202280 patients
N/ACompleted
NCT04828980Oregon TherapeuticsOculus Quest: TRIPP

Utilization of Different Virtual Reality Experiences

Start: Feb 2021Est. completion: Aug 202232 patients
N/ACompleted
NCT04464304Oregon TherapeuticsSmartphone

Virtual Reality for Postoperative Pain Management

Start: Jul 2020Est. completion: Oct 202130 patients
N/ACompleted
NCT04347837Standard BariatricsTitan SGS stapler

Multisite Study of Titan SGS Stapler in Longitudinal Gastric Resection

Start: Jul 2020Est. completion: Dec 202062 patients
N/ACompleted
NCT03984942Nielsen BioSciencesBypass PACU in Knee and Hip Arthroplasty

Bypass PACU in Knee and Hip Arthroplasty

Start: Oct 2019Est. completion: Nov 2020600 patients
N/ACompleted
NCT03891199Nordic PharmaRobotic-Arm Assisted THA

Two Year Study With Robotic-Arm Assisted Hip Surgery.

Start: Apr 2019Est. completion: Aug 202040 patients
N/ACompleted
NCT03776188Apollo TherapeuticsEndoscopic Suturing (ES) Registry

Endoscopic Suturing (ES) Registry

Start: Oct 2018Est. completion: Nov 2021204 patients
N/ACompleted
NCT03706430MasimoPulse CO-Oximeter sensor

Validation of RPVi as a Parameter to Predict Fluid Responsiveness

Start: Sep 2018Est. completion: Oct 202163 patients
N/ATerminated
NCT03276260Medasense BiometricsPMD-200

Evaluation of Medasense's PMD-200 During Surgery and Post Anesthesia Care

Start: Jan 2018Est. completion: Apr 20192 patients
N/ATerminated
NCT02841397MasimoMasimo Pulse CO-Oximeter

Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI

Start: Mar 2017Est. completion: Oct 201750 patients
N/ACompleted
NCT02986789MasimoIn vivo SpHb and PVi Monitoring

Continuous Non-Invasive SpHb and PVI Monitoring on Intra-Operative and Post-Surgical Clinical Outcomes

Start: Dec 2016Est. completion: Aug 201843 patients
N/ATerminated
NCT02954952MasimoPSI Rev 1.X

EEG Data Collection to Evaluate New Patient State Index Performance

Start: Nov 2016Est. completion: Jan 201844 patients
N/ATerminated
NCT03123354MasimoO3 regional oximeter sensor

Calibration and Validation of Masimo's O3 Regional Oximetry Device in Neonates, Infants and Children

Start: May 2015Est. completion: Mar 201744 patients
N/ACompleted
NCT02725788SolventumNew PIV Dressing

Trial Comparing Peripheral I.V. Catheter Complication Rates of Two Different Catheter Dressings

Start: Sep 2014Est. completion: May 2015247 patients
N/ATerminated
NCT01762332Medasense BiometricsBase level of remifentanil effect side concentration: 2ng/ml

Clinical Validation of Medasense Pain Response Index (PRI)

Start: Jan 2013Est. completion: May 201482 patients
N/ACompleted
NCT01820949Fresenius KabiSafety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical Patients

Safety and Effectiveness of a Patient Blood Management (PBM) Program in Surgical Patients

Start: Jan 2013Est. completion: Sep 2015110,000 patients
N/ACompleted
NCT01824706Integra LifeSciencescraniectomy

Prospective, Multicenter Observational Study Evaluating the Long Term Safety of the Custombone Implant

Start: Dec 2012Est. completion: May 2016110 patients
N/ACompleted
NCT03128827MasimoRAM sensor

Use of Rainbow Acoustic Monitoring in Pediatric Patients - A Clinical Engineering Data Collection Protocol

Start: Aug 2011Est. completion: Jul 2015170 patients
N/ACompleted
NCT01631695Medasense BiometricsClinical Evaluation of Medasense Pain Monitor Performances

Clinical Evaluation of Medasense Pain Monitor Performances

Start: Nov 2009Est. completion: May 201296 patients
N/ACompleted
NCT03124901MasimoDCI pulse oximeter sensor

Accuracy of Noninvasive Pulse Oximeter Measurement of Hemoglobin for Rainbow DCI Sensor

Start: Sep 2008Est. completion: Oct 2008147 patients
N/ACompleted
NCT00674388Colorado TherapeuticsThe Pediatric Anesthesia Quality Improvement Project

The Pediatric Anesthesia Quality Improvement Project

Start: Feb 2008Est. completion: Dec 20405,000,000 patients
N/ARecruiting

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

3 actively recruiting trials targeting 5,116,477 patients
30 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.