CENTANY (mupirocin) by Design Pharmaceuticals is clinical pharmacology following the application of centany (mupirocin ointment),2% to a 400 cm area on the back of 23 healthy volunteers once daily for 7 days, the mean (range) cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1. First approved in 2002.
Drug data last refreshed 6h ago · AI intelligence enriched 1w ago
CENTANY (mupirocin) is a topical antibiotic ointment that inhibits bacterial protein synthesis by binding to isoleucyl-tRNA synthetase, making it bactericidal against gram-positive bacteria including Staphylococcus aureus and Streptococcus pyogenes. It is indicated for treatment of skin infections caused by susceptible bacteria. The unique mechanism of action provides no cross-resistance with other antimicrobial classes.
Product is in LOE-approaching phase with moderate competitive pressure (30), signaling shift toward lifecycle management and potential team restructuring.
CLINICAL PHARMACOLOGY Following the application of Centany (mupirocin ointment),2% to a 400 cm area on the back of 23 healthy volunteers once daily for 7 days, the mean (range) cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1.25% (0.2% to 3.0%) of the…
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The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.
Indication data is being enriched from DailyMed and FDA labeling. Check back soon for approved therapeutic uses.
Mupirocin to Reduce Staphylococcus Aureus Colonization in Infants Hospitalized in a NICU
Study to Assess Eradication of Nasal Carriage of Staphylococcus Aureus (SA) With Mupirocin (Bactroban 2% Nasal Ointment)
Safety and Efficacy of Mupirocin in Eradicating Colonization With S. Aureus in Critically Ill Infants
Impact of Mupirocin Decolonization on the Nasal Microbiome
Prevention of Surgical Site Infections: Effectiveness of Nasal Povidone-Iodine and Nasal Mupirocin
Roles linked to CENTANY are primarily in commercial and lifecycle management, not clinical development or growth initiatives. Working on this product offers experience in managing mature/declining products, generic defense strategies, and market access optimization—valuable for career transition to turnaround or portfolio management roles.