NDATOPICALOINTMENT
Approved
Dec 2002
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
7
Data completeness
3/8 — Basic
CENTANY (mupirocin) by Design Pharmaceuticals is clinical pharmacology following the application of centany (mupirocin ointment),2% to a 400 cm area on the back of 23 healthy volunteers once daily for 7 days, the mean (range) cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1. First approved in 2002.
Drug data last refreshed 7h ago · AI intelligence enriched 1w ago
AI summarySynthesized from FDA + DailyMed + ClinicalTrials.gov data
Centany (mupirocin) is a topical antibiotic ointment that inhibits bacterial protein synthesis by binding to isoleucyl-tRNA synthetase, making it bactericidal against gram-positive bacteria including S. aureus and S. pyogenes. It is indicated for skin infections caused by susceptible strains and is applied directly to affected areas. The unique mechanism of action prevents cross-resistance with other antimicrobial classes, though plasmid-mediated resistance is increasingly observed.
LOE Approaching
Product is approaching loss of exclusivity with moderate competitive pressure (30/100), signaling potential team consolidation and transition focus.
Mechanism of Action
CLINICAL PHARMACOLOGY Following the application of Centany (mupirocin ointment),2% to a 400 cm area on the back of 23 healthy volunteers once daily for 7 days, the mean (range) cumulative urinary excretion of monic acid over 24 hrs following the last administration was 1.25% (0.2% to 3.0%) of the…
Indications
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.