Staphylococcal Infections
4
Pipeline Programs
4
Companies
5
Clinical Trials
0
Approved Products
Pipeline by Development Stage
Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
3
1
0
0
0
0
Early DiscoveryClinical DevelopmentMarket
Drug Modality Breakdown
Vaccine
267%
Peptide
133%
+ 2 programs with unclassified modality
Competitive Landscape
4 companies ranked by most advanced pipeline stage
AM-PharmaNetherlands - Utrecht
1 program1
human lactoferrin peptide 1-11Phase 1/2Peptide1 trial
Active Trials
United TherapeuticsMD - Silver Spring
2 programs2
NDV-3 investigational vaccinePhase 1Vaccine1 trial
NDV-3 vaccine with alum IMPhase 1Vaccine1 trial
Active Trials
Trial Timeline
Clinical trial activity over time
2021
2022
2023
2024
2025
2026
AM-Pharmahuman lactoferrin peptide 1-11
United TherapeuticsNDV-3 vaccine with alum IM
United TherapeuticsNDV-3 investigational vaccine
Merck & Co.V710
Pfizerlinezolid
Clinical Trials (5)
Total enrollment: 1,272 patients across 5 trials
A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Bacteremia Due to S. Epidermidis
Start: Feb 2009Est. completion: Oct 2009
Phase 1/2Withdrawn
Effect of Adjuvant & Route of Administration on Safety & Immunogenicity of NDV-3 Vaccine
Start: Sep 2011Est. completion: Dec 2012164 patients
Phase 1Completed
Safety and Immunogenicity Study of a Recombinant Protein Vaccine (NDV-3) Against S.Aureus and Candida
Start: Jan 2011Est. completion: Dec 201140 patients
Phase 1Completed
Safety, Tolerability, and Immunogenicity of a Single Dose of Merck 0657nI Staphylococcus Aureus Vaccine With or Without Merck Aluminum Adjuvant (V710-002)
Start: Sep 2006Est. completion: Oct 200764 patients
Phase 1Completed
Drug Use Investigation Of Zyvox (Linezolid) (Regulatory Post Marketing Commitment Plan)
Start: Feb 2007Est. completion: Apr 20111,004 patients
N/ACompleted
Phase Legend
Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available
Key Insights
4 companies competing in this space