ALTRENO

Peak

tretinoin

NDATOPICALLOTION
Approved
Aug 2018
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
18

Mechanism of Action

nucleus. Tretinoin activates three members of the retinoic acid (RAR) nuclear receptors (RARα, RARβ, and RARγ) which act to modify gene expression, subsequent protein synthesis, and epithelial cell growth and differentiation. It has not been established whether the clinical effects of tretinoin are…

Pharmacologic Class:

Retinoid

Clinical Trials (5)

NCT07341659N/AActive Not Recruiting

Efficacy of Cosmetic Product RV3278B-OS0386 in the Maintenance Phase After Oral Isotretinoin Treatment of Adults Subjects With Facial Acne.

Started Feb 2025
102 enrolled
Acne
NCT04353180Phase 3Unknown

Assessment the Activity Value of Isotretinoin (13- Cis-Retinoic Acid ) in the Treatment of COVID-19 ( Isotretinoin in Treatment of COVID-19) (Randomized)

Started Aug 2021
100,000 enrolled
COVID19
NCT04096742Phase 4Unknown

Altreno for Chest Rejuvenation

Started Aug 2019
40 enrolled
Photodamaged SkinPhotoaging
NCT02498288Phase 1Completed

A Study to Determine Bioequivalence of Isotretinoin in Healthy Male Subjects Under Fed Condition

Started May 2013
36 enrolled
Acne Vulgaris
NCT01863615Phase 1Completed

Bioequivalence Study for an Isotretinoin

Started Aug 2011
36 enrolled
Skin Infections (Acne)

Loss of Exclusivity

LOE Date
Aug 22, 2038
151 months away
Patent Expiry
Aug 22, 2038

Patent Records (2)

Patent #ExpiryTypeUse Code
10653656
Aug 22, 2038
Product
U-2368
11324710
Aug 22, 2038
U-2368