NDAORALTABLET, EXTENDED RELEASE
Approved
Jun 1965
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
20
Data completeness
4/8 — Partial
8-HOUR BAYER (aspirin) by Bayer is [acetylsalicylic acid (asa)] inhibits prostaglandin synthesis resulting in inhibition of platelet aggregation for their lifespan of about 7-10 days. Approved for coronary artery disease, myocardial infarction, stroke and 8 more indications. First approved in 1965.
Drug data last refreshed 20h ago
Mechanism of Action
[acetylsalicylic acid (ASA)] inhibits prostaglandin synthesis resulting in inhibition of platelet aggregation for their lifespan of about 7-10 days. The acetyl group of aspirin binds with a serine residue of cyclooxygenase-1 (COX-1) , resulting in irreversible inactivation of the enzyme. Inhibition…
Indications (11)
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Data Sources
- Drug label: DailyMed / FDA
- Clinical trials: ClinicalTrials.gov
- Patent data: FDA Orange Book
- Spending data: CMS Medicare
The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.