Thesis Work, 30 Credits - Advancing Roller Compaction Simulation in Drug Development

Are you passionate about advancing pharmaceutical manufacturing through process simulation and data analysis? We offer an exciting thesis opportunity to develop and apply roller compaction simulation for early drug product development, optimizing process parameters, material characterization, and formulation design—all while leveraging digital tools and in silico modeling to drive innovation in drug development! 

About AstraZeneca:  

AstraZeneca is a global, science-led, patient-centred biopharmaceutical company focusing on discovering, developing, and commercializing prescription medicines for some of the world’s most serious diseases. But we’re more than a global leading pharmaceutical company. At AstraZeneca, we're dedicated to being a Great Place to Work and empowering employees to push the boundaries of science and fuel their entrepreneurial spirit.   

About the Opportunity:  

As a Thesis Worker at AstraZeneca, you’ll find an environment that’s full of unique opportunities and exciting challenges. Here, you’ll have the opportunity to pursue your areas of interest whilst equally developing a broad skillset and knowledge base to get the best out of your experience. You’ll be working on meaningful projects to make an impact and deliver real value for our patients and our business.  

Thesis work description:   

This project will advance the use of roller compaction simulation to accelerate drug product development. Miniaturization  significantly reduce drug substance usage, making drug product development available earlier and at a lower cost. You will investigate roller compaction process design and key process parameters optimization using miniaturized simulations . Material characterization methods—including particle size distribution and flow properties—will be used to evaluate comparisons between processes. The project can also employ digital tools for thorough data analysis and process modelling to support the development of innovative manufacturing strategies. 

Key Objectives: 

• Utilize miniaturized roller compaction simulations to investigate and optimize full scale process. 
• Evaluate and compare material characterization methods, such as particle size distribution and flow properties, to inform process development. 
• Map integration of roller compaction simulation into the formulation development workflow. 
• Employ digital tools and analytics to assess and interpret process data effectively. 
• Combine simulated trials with in-silico modeling to enhance process understanding. 
• Support the development and implementation of innovative manufacturing strategies by leveraging simulation and modeling insights. 

Placement: 

This is an on-site position at AstraZeneca Gothenburg. AstraZeneca does not support with accommodations for this role.  

Structure:  

Duration: Fall  term 2026  

Credits: 30  

  

Essential Requirements:  

• Enrolled in a Master's program within Pharmacy, Process Engineering, Chemistry or other relevant fields 
• Excellent English communication skills, including speaking, presenting and scientific writing. 
• Laboratory skills 
• Skilled in data interpretation, as well as organizing and processing raw data. 
• Ability to independently organise, plan and execute work tasks. 

So, what’s next?   

Apply today and take the chance to be part of making a difference, making connections, and gaining the tools and experience to open doors and fulfil your potential. We can´'t wait to hear from you!   

We welcome your application as soon as possible, but ahead of the scheduled closing date 20th of April 2026. In the event that we identify suitable candidates ahead of the scheduled closing date, we reserve the right to withdraw the vacancy earlier than published.   

Date Posted

30-Mar-2026

Closing Date

20-Apr-2026

Our mission is to build an inclusive and equitable environment. We want people to feel they belong at AstraZeneca and Alexion, starting with our recruitment process. We welcome and consider applications from all qualified candidates, regardless of characteristics. We offer reasonable adjustments/accommodations to help all candidates to perform at their best. If you have a need for any adjustments/accommodations, please complete the section in the application form.