Principal Software Engineering Lead

Unified Trial Solution – Clinical Trial Site and Investigator | Evinova (AstraZeneca Group)

About Evinova:

Are you ready to be part of the future of healthcare? Can you think big, be bold, and harness the power of digital and AI to tackle longstanding life sciences challenges? Then Evinova, a health tech business within the AstraZeneca Group, might be for you.

We are building software that transforms clinical trials for billions of patients worldwide. Evinova delivers market-leading digital health solutions that are science-based, evidence-led, and committed to human experience. We combine deep scientific expertise with modern software engineering and artificial intelligence to create new standards across the sector.

About Our Engineering Organization:

Our Product Engineering organization consists of multi-functional squads with the people and skills needed to deliver innovative digital products to patients and healthcare providers in clinical trials worldwide. We ship on quarterly program increments using agile methodologies.

We are proud to have one of the strongest software development teams in the health tech space, with deep technical and domain expertise. This is a place where you can build meaningful products, solve complex problems, and grow alongside engineers who care deeply about their craft and its impact.

About the Role:

This is not a traditional management role. We are seeking a hands-on engineering leader who actively writes and reviews code, makes architectural decisions, and leads by building alongside their team.

You will own the technical direction and delivery of the Clinical Trial Site and Investigator product areas within Unified Trial Solution while leading a multi-squad engineering organization. You will spend a significant portion of your time in the codebase, reviewing pull requests, partnering with engineers on complex challenges, evaluating AI-assisted development workflows, and ensuring scalable architecture. The remainder of your time will be focused on team development, cross-functional collaboration, and technical strategy.

We are looking for someone who can serve as the strongest technical voice within their product area and provide clear technical leadership across architecture, delivery, and engineering excellence.

Key Responsibilities

Hands-On Technical Leadership (50%+ of Time):

• Review pull requests, provide code-level feedback, and enforce engineering quality standards.
• Own architectural decisions across APIs, data models, service boundaries, and infrastructure.
• Write production-ready code for complex and foundational platform components.
• Partner with engineers to solve challenging technical problems while coaching and mentoring.
• Drive adoption of AI-assisted development tools, workflows, and best practices.
• Define and maintain standards for testing, CI/CD, observability, and deployment practices.
• AI-Native Engineering Culture
• Integrate AI tools into daily software development workflows.
• Evaluate and implement AI capabilities across Clinical Trial Site and Investigator products.
• Ensure AI-generated code is reviewed, tested, and held to the same quality standards as human-written code.
• Stay current with advancements in AI-assisted development and translate them into practical team improvements.

Team Leadership and Development

• Lead, mentor, and develop a multi-squad engineering organization.
• Build technical leadership capability within squad leads and senior engineers.
• Conduct technical interviews and assess candidates’ engineering capabilities.
• Foster a culture of continuous improvement, psychological safety, and accountability.
• Manage performance through clear expectations focused on quality, impact, and delivery.

Product and Delivery Leadership:

• Partner closely with Product Owners, Product Managers, Design, Clinical Operations, and other stakeholders.
• Translate clinical and business needs into scalable technical solutions.
• Provide technical insight on prioritization, architecture, risk, and long-term maintainability.
• Influence product direction through data, experimentation, clinical understanding, and engineering expertise.
• Drive predictable, high-quality delivery against quarterly objectives.
• Collaborate across the Unified Trial Solution organization to ensure architectural consistency and platform reuse.

Minimum Qualifications

• 8+ years of professional software engineering experience with a proven record of delivering production systems.
• 3+ years of experience leading engineering teams while remaining hands-on with software development.

Deep expertise in at least one of the following technology stacks:

• React / React Native
• Node.js
• Java
• AWS Cloud Services
• Strong architectural leadership across frontend, backend, and infrastructure components.
• Practical experience using AI-assisted development tools such as GitHub Copilot, Claude, Cursor, or similar technologies.
• Strong understanding of Agile delivery methodologies, including Scrum, Kanban, or SAFe.
• Bachelor's or Master's degree in Computer Science, Engineering, or equivalent experience.

Preferred Qualifications

• Experience delivering AI/ML capabilities in production environments, including LLM-powered or agentic AI solutions.
• Experience building software for healthcare professionals, clinical researchers, clinical trial operations, or site-facing applications.
• Familiarity with regulated software development environments, including GxP and SaMD.
• Experience with remote patient monitoring solutions and clinician-facing data visualizations.
• Contributions to open-source projects or demonstrated technical thought leadership.
• Clinical research industry experience.

What This Role Is Not

• A people-management role disconnected from software development.
• A project management role focused on timelines and coordination.
• A superficial AI adoption initiative. We seek someone who has meaningfully integrated AI into their development practices and can lead others to do the same.

Why Evinova?

Evinova draws upon AstraZeneca's extensive experience in developing innovative therapeutics, informed by insights from patients and clinical researchers worldwide. Together, we are accelerating the delivery of life-changing medicines and transforming clinical trial experiences through digital innovation.

We operate with a hybrid working model and expect employees to work from the office a minimum of three days per week, fostering collaboration, innovation, and connection while maintaining flexibility.

Join us as we build a new kind of health technology business and redefine what is possible for patients, healthcare professionals, and the life sciences industry.

Date Posted

02-Oct-2026

Closing Date

14-Oct-2026

AstraZeneca embraces diversity and equality of opportunity.  We are committed to building an inclusive and diverse team representing all backgrounds, with as wide a range of perspectives as possible, and harnessing industry-leading skills.  We believe that the more inclusive we are, the better our work will be.  We welcome and consider applications to join our team from all qualified candidates, regardless of their characteristics.  We comply with all applicable laws and regulations on non-discrimination in employment (and recruitment), as well as work authorization and employment eligibility verification requirements.