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The Position

Developing enzymes for Roche internally as well as externally means for us the development of tailor-made biocatalysts and biological targets for creating the best-in-class molecules for Roche and our clients. Combining several biotechnological methods such as expression profiling, cell cultivation, enzyme purification portfolio, enzyme engineering and biochemical investigations, we always try to improve, to maintain or to design new enzymes. Mandatory, the complete value chain as a platform thought of Roche is given. We are working cross-functional for both the diagnostic and pharma division of Roche worldwide. Being an R&D function we always try to keep close contacts with our clients as with our production for ensuring a fast, but qualitatively high development which should result in functional Roche products finally.

As a Post-Doc Position in Novel Enzymes (m/f/d), you actively shape the development of new enzymes using biotechnological and bioinformatic methods. Become part of an innovative research team that consolidates a platform from dry-lab to wet-lab to develop customized enzymes for our diagnostics. We offer you a unique opportunity to translate your scientific ideas into practice and thus contribute to the improvement of patient health.

The opportunity

• You ensure the development of new enzymes using a combination of biotechnological and bioinformatic methods

• You are responsible for the independent production of tailored proteins/enzymes using molecular biological methods or the establishment of new production and screening methods for protein variants

• You support the consolidation of a platform from dry-lab to wet-lab, suitable for the protein engineering of novel enzymes

• You implement new biochemical and biophysical readouts suitable for the screening and development of tailored enzymes

• You pursue scientific and technical education by continuously following and reading the relevant scientific literature

Who you are

• You possess a university degree (Dr. / Ph.D.) in a relevant field

• You have specialized knowledge in the areas of protein engineering, bioinformatics, and molecular biology

• Experience in microbiology, downstream and upstream processing, as well as chemistry, is an advantage

• You demonstrate knowledge and expertise in recombinant protein expression, protein purification, and the development of protein analytical methods for protein characterization

• You are willing to provide consultation and troubleshooting regarding enzyme challenges in Research & Development and Production

This position is limited to 2 years.

Application documents

To make the application process as convenient as possible for you please add only a motivation letter and your updated CV. References and certificates are not required at this stage.

We look forward to receiving your application!

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Who we are

A healthier future drives us to innovate. Together, more than 100’000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let’s build a healthier future, together.