Formulation Senior Research Associate

Job Description

General Summary:

The Formulation Senior Research Associate will perform an array of activities working with other scientists to advance drug candidates from exploratory development through commercial line extension in a Quality by Design (QbD) environment using lab based and computational tools.

Key Duties and Responsibilities:

• Contribute to the development of solid dosage forms for clinical and commercial use, generate data for project progression and regulatory filings, conduct a range of activities for optimization and scale up studies
• Help execute, and interpret laboratory experiments, with minimal supervision, to meet established project timelines
• Maintain accurate and complete laboratory notebook capturing protocols, results and observations
• Interpret data to form sound conclusions
• Timely document integrated experimental outcomes in presentations and research reports
• Perform basic statistical analysis of experimental data
• Assist in technical transfer to CMO partners for clinical trial manufacture
• Initiate experimental troubleshooting on routine problems, with minimal supervision
• Contribute to drafting regulatory filing documentation
• Comply with all relevant Safety and GMP procedures

Knowledge and Skills:

• Sound technical knowledge of pharmaceutical and engineering principles in the solid dosage form development for both clinical and commercial scales
• Hands on experience with formulation techniques, processing equipment, and unit operations at both the laboratory and clinical manufacturing scales
• Strong math skills particularly as applied to material/energy balances, and intermediate applied statistical analysis
• Strong technical writing skills
• Strong verbal and written communication skills
• Successful and efficient multitasking and ability to work on a few projects concurrently
• Detail-oriented
• Direct experience working with CMOs is a plus
• Understanding of QbD and experience with Regulatory filings is a plus
• Strong background in oral solid form development and good understanding of material properties

Education and Experience:

• Bachelor’s degree in pharmaceutical, material science or chemical engineering field
• Master's Degree in pharmaceutical sciences, chemistry, chemical engineering, materials sciences or related field and 0-2 years experience in life sciences, engineering or academia, or
• Bachelor's Degree in pharmaceutical sciences, chemistry, chemical engineering, materials sciences or related field and 4 years experience in life sciences, engineering or academia

At Vertex, we embrace continuous learning and encourage employees to stay informed on advances in AI, technology, automation, and industry trends. We seek talent who bring an external perspective, demonstrate curiosity and sound judgment, and thoughtfully adopt new capabilities that improve decision-making, drive innovation, increase efficiency, and help deliver better outcomes for patients.

Pay Range:

$74,000 - $111,000

Disclosure Statement:

Flex Designation:

On-Site Designated

Flex Eligibility Status:

In this On-Site designated role, you will work five days per week on-site with ad hoc flexibility.  

Note: The Flex status for this position is subject to Vertex’s Policy on Flex @ Vertex Program and may be changed at any time.

#LI-Onsite

Company Information

Vertex is a global biotechnology company that invests in scientific innovation.

Vertex is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, sex, gender identity or expression, age, religion, national origin, ancestry, ethnicity, disability, veteran status, genetic information, sexual orientation, marital status, or any characteristic protected under applicable law. Vertex is an E-Verify Employer in the United States. Vertex will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

Any applicant requiring an accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied should make a request to the recruiter or hiring manager, or contact Talent Acquisition at ApplicationAssistance@vrtx.com