Executive Director, Head of Data Analytics

<div class="content-intro"><p><strong><span data-contrast="auto">About Us</span></strong><span data-ccp-props="{}"> </span></p> <div data-olk-copy-source="MessageBody">Kardigan is a heart health company working to make cardiovascular disease preventable, curable and no longer the leading cause of death in the world.<br><br></div> <div>It is Kardigan’s mission to develop multiple targeted treatments in parallel that bring people with cardiovascular diseases to the cures they deserve.</div> <div> </div> <div>Led by Tassos Giannakakos, Jay Edelberg, <span data-olk-copy-source="MessageBody">M.D., Ph.D.,</span> and Bob McDowell, Ph.D., Kardigan’s co-founders have reunited after leading MyoKardia to discover and develop mavacamten, the first cardiac myosin inhibitor, resulting in an acquisition by Bristol Myers Squibb in 2020.</div> <div> </div> <div>We have a cutting-edge discovery and translational research platform, a pipeline of late-stage candidates, and an industry-leading team that is driven to improve the lives of patients.</div> <div> </div> <div>At Kardigan, we are motivated by our values which guide how we work, interact, and achieve our goals. <strong>Driven by patients and their families</strong>, we are deeply committed to improving the lives of patients and prioritizing their needs above all else. We believe in <strong>being authentic</strong>—leading with truth to bring out the best in others by creating an environment where every person knows they will be fully accepted. With an <strong>eagerness to learn</strong>, we encourage the highest levels of curiosity and are open to changing our minds. We are committed to <strong>winning as a team</strong> with urgency, excellence, and intention, and support each other no matter what role we play or where we sit. Lastly, we strive to <strong>enable the impossible</strong> because patients are counting on us. We are not afraid to take risks to unlock innovation and advance scientific discoveries.</div> <div> </div> <div>These values are the foundation of our work, empowering us to make a real difference, every day.</div> <div> </div> <div> </div></div><p><strong>Reports To: </strong>  VP, Biometrics</p> <p><strong>Location: </strong>Princeton, NJ – On-site 4 days per week (Mon to Thurs) </p> <p><strong>Position Summary</strong></p> <p>The Head of Data Analytics is a strategic leader responsible for the architectural vision and operational execution of data delivery and advanced insights at Kardigan. This role reports to the head of Biometrics and unites <strong>Statistical Programming</strong> and <strong>Data Science</strong> into a single, cohesive engine. You will build, lead, and develop a high-performing team, and lead the modernization of our Stats Programming & Data Science infrastructure—bridging traditional SAS-based regulatory production with R-based data science—to create real-time, automated dashboards that accelerate decision-making across our cardiovascular pipeline.</p> <p>The Head of Data Analytics serves as a thought-leader in advanced analytics, ensuring high-quality, compliant data deliverables while enabling predictive insights, automation, and scalable analytics platforms.</p> <p>This position will also be responsible for departmental & organizational strategic initiatives.</p> <p><strong>Essential Duties and Responsibilities</strong> </p> <ul> <li>Develop the Data Analytics function and strategy aligned with the organizations clinical development goals. Lead the recruitment, on-boarding, and management of staff and external vendors and consultants </li> <li>Ensure data interpretation and statistical analysis support high-integrity decision making and regulatory submissions</li> </ul> <ul> <li>Partner closely with Biostatistics, Medical, Clinical Operations, Safety, and Regulatory to ensure insights inform decision making and strategy</li> <li><strong>Modernization Roadmap:</strong> Define and execute the strategy to transition from legacy programming silos to a modern, hybrid R/SAS environment.</li> <li><strong>Platform Ownership:</strong> Lead the design and deployment of an internal analytics platform (e.g., R-Shiny, Spotfire) to provide cross-functional teams (Clinical, Safety,  Operations) with real-time, self-service data review capabilities.</li> </ul> <ul> <li><strong>Regulatory Quality:</strong> Oversee the internal team or CRO delivering SDTM, ADaM, and TFLs for regulatory submissions (IND, NDA/MAA). </li> <li><strong>Submission Strategy:</strong> Develop strategies for electronic submission packages, ensuring "inspection-readiness" is built into the data pipeline.</li> <li>Partner with Biostatistics to ensure alignment between analysis plans, programming execution, and advanced analytics approaches.</li> </ul> <ul> <li><strong>Process Engineering:</strong> Drive "Lean Programming" by leveraging automation to reduce turnaround times to support data monitoring activities.</li> <li><strong>Standardization:</strong> Develop a library of reusable R-packages and SAS macros to ensure reproducibility and consistency across all clinical programs.</li> <li>Establish best practices, SOPs, and governance frameworks for analysis across programs</li> <li>Ability to assess and transform capabilities through AI and Automation solutions or strategies </li> <li>Up to 20-30% domestic and international travel may be required</li> </ul> <p><strong>Qualifications and Preferred Skills</strong> </p> <ul> <li><strong>M.S. </strong>in Biostatistics, Data Science, Computer Science, or a related quantitative field is required. </li> <li>PhD preferred.</li> <li><strong>12+ years</strong> in Biometrics/Clinical Analytics, with at least <strong>5 years</strong> in a leadership role within a biotech or pharma environment.  Or 10+ yrs with a PhD</li> <li><strong>Cardiovascular Domain Expertise:</strong> Deep understanding of the unique data challenges in CV trials (e.g., longitudinal endpoints, high-frequency monitoring data).</li> </ul> <ul> <li>Strong knowledge and hands-on technical expertise of SQL, Python/R, and visualization tools</li> <li>Prior experience working in small fast-paced company highly preferred. </li> </ul> <ul> <li>Extensive experience in drug development and working with regulatory agencies such as FDA and EMA for submissions.</li> </ul> <ul> <li>Hands-on exposure to modern analytics platforms, cloud environments, and AI/ML enablement in clinical development</li> </ul> <ul> <li>Experience working in an environment where knowledge of and adherence to SOPs and regulatory guidelines are required </li> </ul> <ul> <li>Excellent collaborator, communicator (verbal & written), and influencer across technical and non-technical audiences</li> </ul> <ul> <li>Detail and process oriented and demonstration of strong project management skills. </li> <li>Demonstrated success in building & leading high-performing teams and driving change in a corporate environment</li> </ul><div class="content-pay-transparency"><div class="pay-input"><div class="description"><p>Exact Compensation may vary based on skills, experience and location.</p></div><div class="title">Pay range</div><div class="pay-range"><span>$260,000</span><span class="divider">—</span><span>$338,000 USD</span></div></div></div>