CAMZYOS

Peak

mavacamten

NDAORALCAPSULE
Approved
Apr 2022
Lifecycle
Peak
Competitive Pressure
0/100
Clinical Trials
20

Mechanism of Action

Cardiac Myosin Inhibitors

Pharmacologic Class:

Cardiac Myosin Inhibitor

Indications (1)

Clinical Trials (5)

NCT07361289N/ARecruiting

A Study to Assess the Real-World Effectiveness of Mavacamten in Adult Patients With Obstructive Hypertrophic Cardiomyopathy in China

Started Jan 2026
500 enrolled
Hypertrophic Cardiomyopathy
NCT07004972Phase 4Recruiting

A Study of Mavacamten in Adults With Obstructive Hypertrophic Cardiomyopathy in India (ROVER)

Started Sep 2025
50 enrolled
Symptomatic Obstructive Hypertrophic Cardiomyopathy
NCT07383025N/ARecruiting

Mavacamten Post-marketing Surveillance in Patients With Obstructive Hypertrophic Cardiomyopathy in Japan

Started May 2025
200 enrolled
Obstructive Hypertrophic Cardiomyopathy (oHCM)
NCT06146660N/ARecruiting

A Study to Assess the Safety of Mavacamten in Korean Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy

Started Jul 2024
600 enrolled
Obstructive Hypertrophic Cardiomyopathy
NCT06338202N/ACompleted

Real-World Effectiveness of Mavacamten in Canada

Started Jun 2024
115 enrolled
Obstructive Hypertrophic Cardiomyopathy (oHCM)

Loss of Exclusivity

LOE Date
Apr 28, 2036
123 months away
Patent Expiry
Apr 28, 2036
Exclusivity Expiry
Apr 28, 2029

Patent Records (2)

Patent #ExpiryTypeUse Code
9585883
Jun 19, 2034
U-3373
RE50050
Apr 28, 2036
SubstanceProduct