Associate Scientist, Potency Assay Development

Build our future together:

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. The Late-Stage Bioassay group within the Therapeutic Proteins Department is seeking a highly motivated Associate Scientist to support the development, optimization, and qualification of cell-based and molecular assays for our gene therapy pipeline, including AAV, siRNA, and antibody-oligonucleotide conjugate (AOC) programs. In this role, you will develop and optimize potency bioassays to support preclinical and clinical programs, perform sample testing in support of preclinical manufacturing process and product characterization, and help transfer qualified assays to GMP laboratories.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & where:

• Location: Tarrytown, NY

• Work model: Onsite

Discover your role:

• Develop, optimize, and qualify cell-based potency assays to support gene therapy programs.

• Execute qPCR, ELISA, Western blot, and related molecular or cell-based assays with strong attention to detail and reproducibility.

• Maintain healthy adherent and non-adherent mammalian cell cultures, including engineered or stable cell lines used in assay development.

• Operate laboratory instruments such as flow cytometers, plate readers (SpectraMax, EnVision), and other automated systems to support assay execution and data generation.

• Analyze data using appropriate statistical methods and document experiments, results, and conclusions clearly in the electronic lab notebook (ELN).

• Present findings in group and cross-functional meetings and contribute to assay troubleshooting, optimization, and technical decision-making.

• Support sample testing for preclinical manufacturing process and product characterization.

• Help transfer qualified assays to GMP laboratories.

This role requires:

• A Bachelors with at least 3 years of relevant laboratory experience, or a Masters with 0-2 years of experience

• Hands-on experience with cell-based assays, preferably including potency assays.

• Experience with qPCR, ELISA, and CE-Western blotting.

• Strong mammalian cell culture skills and the ability to execute experiments independently and reliably.

• Exceptional organizational skills and the ability to multitask across multiple workflows in a fast-paced environment

• Preferred experience includes mRNA expression measurement using qPCR, Luciferase reporter-based assays, immunofluorescence staining and imaging-based assay readouts, automated imaging or plate-based analytical platforms, and GraphPad Prism data analysis experience

Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all  qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

 

Where necessary, we disclose salary ranges for roles in all countries in which we operate.  The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.  Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.  If you have any questions, please speak with your recruiter. 

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed on‑site. Please speak with your recruiter and hiring manager for more information about on‑site expectations for your role and location.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$70,300.00 - $110,100.00