Venous Ulcer

4
Pipeline Programs
6
Companies
6
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
2
0
0
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

6 companies ranked by most advanced pipeline stage

Organogenesis
OrganogenesisCANTON, MA
1 program
1
ApligrafPhase 41 trial
Active Trials
NCT01327937CompletedEst. Dec 2013
Eagle Pharmaceuticals
Eagle PharmaceuticalsNJ - Woodcliff Lake
1 program
1
OPAL APhase 21 trial
Active Trials
NCT00933348SuspendedEst. Dec 2016
Bayer
BayerLEVERKUSEN, Germany
1 program
1
Silica Gel FiberPhase 21 trial
Active Trials
NCT00998673Terminated121Est. Jun 2011
Design Therapeutics
1 program
1
Bioengineered Artificial Mesenchimal SheetPhase 1/21 trial
Active Trials
NCT05962931UnknownEst. Jul 2025
Tides Medical
Tides MedicalLA - Lafayette
1 program
Artacent Human Amniotic MembraneN/A1 trial
Active Trials
NCT02838784UnknownEst. Dec 2018
Tactile Medical
Tactile MedicalMN - Minneapolis
1 program
Standard Wound CareN/A1 trial
Active Trials
NCT00847002Terminated8Est. Aug 2010

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
OrganogenesisApligraf
Eagle PharmaceuticalsOPAL A
BayerSilica Gel Fiber
Design TherapeuticsBioengineered Artificial Mesenchimal Sheet
Tides MedicalArtacent Human Amniotic Membrane
Tactile MedicalStandard Wound Care

Clinical Trials (6)

Total enrollment: 129 patients across 6 trials

NCT01327937OrganogenesisApligraf

A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers

Start: Mar 2011Est. completion: Dec 2013
Phase 4Completed
NCT00933348Eagle PharmaceuticalsOPAL A

Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers

Start: Jan 2010Est. completion: Dec 2016
Phase 2Suspended
NCT00998673BayerSilica Gel Fiber

Silica Gel Fiber Wound Dressing for Chronic Venous Leg Ulcers

Start: Apr 2009Est. completion: Jun 2011121 patients
Phase 2Terminated
NCT05962931Design TherapeuticsBioengineered Artificial Mesenchimal Sheet

Clinical Trial With Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lower Limbs

Start: Jul 2023Est. completion: Jul 2025
Phase 1/2Unknown
NCT02838784Tides MedicalArtacent Human Amniotic Membrane

Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers

Start: Sep 2016Est. completion: Dec 2018
N/AUnknown
NCT00847002Tactile MedicalStandard Wound Care

Flexitouch Treatment for Venous Ulcers

Start: Sep 2007Est. completion: Aug 20108 patients
N/ATerminated

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

6 companies competing in this space