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Venous Ulcer

2
Pipeline Programs
8
Companies
8
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
0
1
1
0
0
0
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

8 companies ranked by most advanced pipeline stage

Bayer
BayerLEVERKUSEN, Germany
1 program
1
Silica Gel FiberPhase 21 trial
Active Trials
NCT00998673Terminated121Est. Jun 2011
Design Pharmaceuticals
1 program
1
Bioengineered Artificial Mesenchimal SheetPhase 1/2
Solventum
SolventumMN - St. Paul
2 programs
Coban 2N/A1 trial
Coban 2 Layer Compression SystemN/A1 trial
Active Trials
NCT00558662Completed234Est. Sep 2011
NCT00301496Completed80Est. Apr 2007
Tides Medical
Tides MedicalLA - Lafayette
1 program
Artacent Human Amniotic MembraneN/A1 trial
Active Trials
NCT02838784Unknown134Est. Dec 2018
Tactile Medical
Tactile MedicalMN - Minneapolis
1 program
Standard Wound CareN/A1 trial
Active Trials
NCT00847002Terminated8Est. Aug 2010
Design Therapeutics
1 program
Bioengineered Artificial Mesenchimal SheetPHASE_1_21 trial
Active Trials
NCT05962931Unknown20Est. Jul 2025
Eagle Pharmaceuticals
Eagle PharmaceuticalsNJ - Woodcliff Lake
1 program
OPAL APHASE_21 trial
Active Trials
NCT00933348Suspended30Est. Dec 2016
Organogenesis
OrganogenesisCANTON, MA
1 program
ApligrafPHASE_41 trial
Active Trials
NCT01327937Completed30Est. Dec 2013

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
OrganogenesisApligraf
Eagle PharmaceuticalsOPAL A
BayerSilica Gel Fiber
Design TherapeuticsBioengineered Artificial Mesenchimal Sheet
Tides MedicalArtacent Human Amniotic Membrane
SolventumCoban 2
Tactile MedicalStandard Wound Care
SolventumCoban 2 Layer Compression System

Clinical Trials (8)

Total enrollment: 657 patients across 8 trials

NCT01327937OrganogenesisApligraf

A Post Marketing Study of Apligraf in Non-healing Wounds of Subjects With Venous Leg Ulcers

Start: Mar 2011Est. completion: Dec 201330 patients
Phase 4Completed
NCT00933348Eagle PharmaceuticalsOPAL A

Safety and Efficacy of the Fruit-based Product OPAL A for the Treatment of Chronic Venous and Pressure Ulcers

Start: Jan 2010Est. completion: Dec 201630 patients
Phase 2Suspended
NCT00998673BayerSilica Gel Fiber

Silica Gel Fiber Wound Dressing for Chronic Venous Leg Ulcers

Start: Apr 2009Est. completion: Jun 2011121 patients
Phase 2Terminated
NCT05962931Design TherapeuticsBioengineered Artificial Mesenchimal Sheet

Clinical Trial With Adipose Tissue Stem Cells on Biological Matrix for the Treatment of Venous Ulcer of the Lower Limbs

Start: Jul 2023Est. completion: Jul 202520 patients
Phase 1/2Unknown
NCT02838784Tides MedicalArtacent Human Amniotic Membrane

Efficacy and Safety of Artacent™ for Treatment Resistant Lower Extremity Venous and Diabetic Ulcers

Start: Sep 2016Est. completion: Dec 2018134 patients
N/AUnknown
NCT00558662SolventumCoban 2

Randomized Clinical Trial (RCT) to Compare the Efficacy of Coban 2 Versus SSB in the Treatment of Venous Leg Ulcers

Start: Nov 2007Est. completion: Sep 2011234 patients
N/ACompleted
NCT00847002Tactile MedicalStandard Wound Care

Flexitouch Treatment for Venous Ulcers

Start: Sep 2007Est. completion: Aug 20108 patients
N/ATerminated
NCT00301496SolventumCoban 2 Layer Compression System

Randomized Controlled 8-week Crossover Evaluation of Compression Bandage Systems for Venous Leg Ulcers

Start: Mar 2006Est. completion: Apr 200780 patients
N/ACompleted

Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

8 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.