Sleep

Pipeline Programs

Companies

Clinical Trials

9 recruiting

Approved Products

Pipeline by Development Stage

Preclinical

Phase 1

Phase 1/2

Phase 2

Phase 2/3

Phase 3

On Market

Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

21 companies ranked by most advanced pipeline stage

Pre

P1/2

P2/3

Mkt

Colorado TherapeuticsCO - Louisville

6 programs

fsCBD CannabidiolPhase 21 trial

Extended Sleep InterventionN/A1 trial

LED portable light therapy bulbN/A1 trial

PBS StudyN/A1 trial

+1 more programs

Active Trials

NCT03814512Completed10Est. Dec 2023

NCT07465250Completed20Est. Jul 2025

NCT04202731Terminated5Est. Jul 2023

+3 more trials

MSDIreland - Ballydine

1 program

Suvorexant 20 mgPhase 21 trial

Active Trials

NCT04629547Recruiting200Est. May 2026

Sharp TherapeuticsPA - Pittsburgh

1 program

Suvorexant 20 mgPhase 2

Oregon TherapeuticsFrance - Paris

6 programs

DronabinolPhase 11 trial

Breathing Group 1N/A1 trial

Construction Virtual Reality Stress ChallengesN/A1 trial

Enhanced CabN/A1 trial

Manipulation of Sleep DurationN/A1 trial

+1 more programs

Active Trials

NCT05756686Completed95Est. Aug 2024

NCT07431970Not Yet Recruiting12Est. Aug 2026

NCT03108599Completed49Est. Aug 2021

+3 more trials

PfizerNEW YORK, NY

1 program

PF-04457845 / matched placeboPhase 11 trial

Active Trials

NCT01002625Terminated18Est. Jan 2010

Angeles TherapeuticsCA - Los Angeles

4 programs

Care2SleepN/A1 trial

Magnesium L-ThreonateN/A1 trial

Sleep AppN/A1 trial

TS-C-STEPN/A1 trial

Active Trials

NCT05452031Recruiting672Est. Aug 2027

NCT07015047Active Not Recruiting100Est. Jul 2026

NCT04487483Unknown101Est. Aug 2020

+1 more trials

Human BioSciencesWV - Martinsburg

4 programs

Infant sleep-adapted coparenting interventionN/A1 trial

Timed evening technology and digital media useN/A1 trial

Transdiagnostic Intervention for Sleep and Circadian DysfunctionN/A1 trial

no screen control with dim light and calming activitiesN/A1 trial

Active Trials

NCT03187561Completed216Est. May 2025

NCT05820555Recruiting180Est. Aug 2026

NCT07461844Not Yet Recruiting24Est. Sep 2027

+1 more trials

PhilipsNetherlands - Amsterdam

3 programs

Philips SmartSleep Technology--Continuous Fixed Interval modalityN/A1 trial

PowersleepN/A1 trial

blue lightN/A1 trial

Active Trials

NCT03911154Completed9Est. Jun 2021

NCT02797678Completed62Est. Jan 2017

NCT02216318Completed29Est. Dec 2013

Cognition TherapeuticsPA - Pittsburgh

2 programs

24/7 EEG™ SubQN/A

Sleep and Wellbeing StudyN/A1 trial

Active Trials

NCT03012685Completed100Est. Apr 2018

Jazz PharmaceuticalsCA - Palo Alto

2 programs

Language of SleepinessN/A1 trial

sodium oxybatePHASE_41 trial

Active Trials

NCT04323254Unknown200Est. Mar 2021

NCT00506974Completed60Est. Jun 2008

Temple TherapeuticsNetherlands - Geleen

2 programs

Optimize SleepN/A1 trial

Sleep TightN/A1 trial

Active Trials

NCT01508793Completed103Est. Nov 2016

NCT06038591Completed60Est. Mar 2025

Design PharmaceuticalsMA - Cambridge

2 programs

PrenaBeltN/A

Design TherapeuticsCARLSBAD, CA

2 programs

PrenaBeltN/A1 trial

Active Trials

NCT02379728Completed200Est. Jun 2016

NCT02377817Completed23Est. Jan 2017

UNEEG MedicalDenmark - Allerod

1 program

24/7 EEG™ SubQN/A1 trial

Active Trials

NCT04513743Completed25Est. Jul 2022

Alliance PharmaceuticalsUK - Wiltshire

1 program

CannabigerolN/A1 trial

Active Trials

NCT05088018Completed68Est. May 2022

Enterprise TherapeuticsUK - Brighton

1 program

Dynamic LightingN/A1 trial

Active Trials

NCT05697757Completed10Est. Jun 2023

ElemindMA - Cambridge

1 program

Elemind NeuromodulationN/A1 trial

Active Trials

NCT05743114Completed200Est. Jan 2024

Purdue PharmaCT - Stamford

1 program

Normal proteinN/A1 trial

Active Trials

NCT03174769Completed71Est. Oct 2019

LabcorpBURLINGTON, NC

1 program

Static Lighting ConditionN/A1 trial

Active Trials

NCT05978934Unknown70Est. Dec 2023

Verily Life SciencesCA - South SF

1 program

Study WatchN/A1 trial

Active Trials

NCT05276362Completed90Est. Sep 2023

Intrinsic TherapeuticsMA - Woburn

1 program

TMS combined with EEGN/A1 trial

Active Trials

NCT07523191Recruiting30Est. May 2027

Trial Timeline

Clinical trial activity over time

2021

2022

2023

2024

2025

2026

2027

2028

2029

2030

2031

Jazz Pharmaceuticalssodium oxybate

Colorado TherapeuticsfsCBD Cannabidiol

MSDSuvorexant 20 mg

Oregon TherapeuticsDronabinol

PfizerPF-04457845 / matched placebo

Human BioSciencesTransdiagnostic Intervention for Sleep and Circadian Dysfunction

Intrinsic TherapeuticsTMS combined with EEG

Oregon TherapeuticsConstruction Virtual Reality Stress Challenges

Angeles TherapeuticsTS-C-STEP

Angeles TherapeuticsMagnesium L-Threonate

Oregon TherapeuticsManipulation of Sleep Duration

Human BioSciencesno screen control with dim light and calming activities

Colorado TherapeuticsLED portable light therapy bulb

Temple TherapeuticsSleep Tight

Showing 15 of 40 trials with date data

Clinical Trials (40)

Total enrollment: 5,347 patients across 40 trials

NCT00506974 Jazz Pharmaceuticalssodium oxybate

Enhancing Slow Wave Sleep With Sodium Oxybate

Start: May 2007Est. completion: Jun 200860 patients

Phase 4Completed

NCT06266611 Colorado TherapeuticsfsCBD Cannabidiol

Cannabis for Palliative Care in Cancer

Start: Sep 2024Est. completion: Jun 2028185 patients

Phase 2Recruiting

NCT06290063 Colorado TherapeuticsfsCBD Cannabidiol

Cannabidiol and Older Adult Cannabis Users

Start: May 2024Est. completion: Aug 2028385 patients

Phase 2Recruiting

NCT04629547 MSDSuvorexant 20 mg

Sleep Trial to Prevent Alzheimer's Disease

Start: May 2022Est. completion: May 2026200 patients

Phase 2Recruiting

NCT03560934 Oregon TherapeuticsDronabinol

Tetrahydrocannabinol (THC) and Sleep

Start: Sep 2018Est. completion: Dec 202518 patients

Phase 1Completed

NCT01002625 PfizerPF-04457845 / matched placebo

A Study To Establish The Effects Of PF-04457845 On Sleep In Healthy Volunteers

Start: Nov 2009Est. completion: Jan 201018 patients

Phase 1Terminated

NCT07461844 Human BioSciencesTransdiagnostic Intervention for Sleep and Circadian Dysfunction

Transdiagnostic Sleep and Circadian Treatment for Autistic Adults

Start: Sep 2026Est. completion: Sep 202724 patients

N/ANot Yet Recruiting

NCT07523191 Intrinsic TherapeuticsTMS combined with EEG

Validation of Presence-IP1.0 for Detection of Consciousness Using Reduced-Montage TMS-EEG

Start: Mar 2026Est. completion: May 202730 patients

N/ARecruiting

NCT07431970 Oregon TherapeuticsConstruction Virtual Reality Stress Challenges

Assessing Construction Execution Under Sleep Impairment

Start: Mar 2026Est. completion: Aug 202612 patients

N/ANot Yet Recruiting

NCT07213908 Angeles TherapeuticsTS-C-STEP

Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

Start: Mar 2026Est. completion: Jun 20301,320 patients

N/ARecruiting

NCT07015047 Angeles TherapeuticsMagnesium L-Threonate

Effects of Magnesium L-Threonate on Sleep, Recovery, and Athletic Performance in Collegiate Athletes

Start: Oct 2025Est. completion: Jul 2026100 patients

N/AActive Not Recruiting

NCT06982950 Oregon TherapeuticsManipulation of Sleep Duration

Cannabis Association With Sleep Study

Start: Jul 2025Est. completion: Jun 203260 patients

N/ANot Yet Recruiting

NCT06192745 Human BioSciencesno screen control with dim light and calming activities

SCREENS: Sleep, Circadian Rhythms, and Electronics in the EveNing Study

Start: Jan 2025Est. completion: Aug 2028220 patients

N/ARecruiting

NCT07465250 Colorado TherapeuticsLED portable light therapy bulb

Effects of Combined Blue and Red Home-Based Light Therapy on Sleep in Adults With Self-Reported Sleep Difficulties

Start: Jul 2024Est. completion: Jul 202520 patients

N/ACompleted

NCT06038591 Temple TherapeuticsSleep Tight

Parent Intervention to Improve Child Sleep

Start: Jan 2024Est. completion: Mar 202560 patients

N/ACompleted

NCT05756686 Oregon TherapeuticsBreathing Group 1

Influence of Yogic Breathwork on Sleep

Start: Sep 2023Est. completion: Aug 202495 patients

N/ACompleted

NCT05978934 LabcorpStatic Lighting Condition

Determining How Indoor Lighting Affects the Brain Health of Older Adults

Start: May 2023Est. completion: Dec 202370 patients

N/AUnknown

NCT05820555 Human BioSciencesTimed evening technology and digital media use

The Goodnight Screen Media Study

Start: Apr 2023Est. completion: Aug 2026180 patients

N/ARecruiting

NCT05697757 Enterprise TherapeuticsDynamic Lighting

Lighting for Older Adults With Dementia

Start: Jan 2023Est. completion: Jun 202310 patients

N/ACompleted

NCT05452031 Angeles TherapeuticsCare2Sleep

A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

Start: Nov 2022Est. completion: Aug 2027672 patients

N/ARecruiting

NCT05276362 Verily Life SciencesStudy Watch

Study Watch Sleep Metric Performance Characterization Study

Start: Mar 2022Est. completion: Sep 202390 patients

N/ACompleted

NCT05088018 Alliance PharmaceuticalsCannabigerol

Swallowable Cannabigerol Tablets for Sleep Quality In Veterans (Veterans Exploring Cannabigerol for Sleep)

Start: Oct 2021Est. completion: May 202268 patients

N/ACompleted

NCT04804124 Oregon TherapeuticsRegularized Sleep Schedule

Sleep Duration and Cardiovascular Health

Start: Jun 2021Est. completion: Mar 202624 patients

N/ARecruiting

NCT04513743 UNEEG Medical24/7 EEG™ SubQ

Ultra Long-Term Sleep Monitoring Using UNEEG™ Medical 24/7 EEG™ SubQ

Start: Sep 2020Est. completion: Jul 202225 patients

N/ACompleted

NCT04323254 Jazz PharmaceuticalsLanguage of Sleepiness

Language of Sleepiness

Start: Mar 2020Est. completion: Mar 2021200 patients

N/AUnknown

NCT04487483 Angeles TherapeuticsSleep App

Exploring the Impact of a Sleep App on Sleep Quality

Start: Feb 2020Est. completion: Aug 2020101 patients

N/AUnknown

NCT05743114 ElemindElemind Neuromodulation

Sounds Locked to ElectroEncephalogram Phase For the Acceleration of Sleep Onset Time

Start: Feb 2020Est. completion: Jan 2024200 patients

N/ACompleted

NCT04202731 Colorado TherapeuticsPBS Study

Sleep, Insulin Sensitivity, and Weight in Adolescents Post-bariatric Surgery

Start: Nov 2019Est. completion: Jul 20235 patients

N/ATerminated

NCT03911154 PhilipsPhilips SmartSleep Technology--Continuous Fixed Interval modality

Evaluation of SmartSleep Technology for Improving the Efficiency and Restorative Quality of Sleep in Healthy Adults

Start: Apr 2019Est. completion: Jun 20219 patients

N/ACompleted

NCT03814512 Colorado TherapeuticsExtended Sleep Intervention

Improving Insulin Resistance and Energy Metabolism Through Sleep Extension in Adolescents

Start: Mar 2019Est. completion: Dec 202310 patients

N/ACompleted

NCT03187561 Human BioSciencesInfant sleep-adapted coparenting intervention

Coparenting, Infant Sleep, and Infant Development

Start: Nov 2018Est. completion: May 2025216 patients

N/ACompleted

NCT03174769 Purdue PharmaNormal protein

Impact of Protein Quantity Within the USDA Healthy Style Eating Pattern on Sleep

Start: May 2017Est. completion: Oct 201971 patients

N/ACompleted

NCT03108599 Oregon TherapeuticsEnhanced Cab

Tech4Rest Trial With Team Truck Drivers

Start: May 2017Est. completion: Aug 202149 patients

N/ACompleted

NCT03012685 Cognition TherapeuticsSleep and Wellbeing Study

Sleep and Wellbeing Study

Start: Nov 2016Est. completion: Apr 2018100 patients

N/ACompleted

NCT03330093 Colorado TherapeuticsSleep Health in Preschoolers

Sleep and Emotion Processing in Childhood

Start: Aug 2016Est. completion: Jul 201923 patients

N/ACompleted

NCT02797678 PhilipsPowersleep

Feasibility, Effectiveness and Efficacy of the PowerSleep Device

Start: Jun 2016Est. completion: Jan 201762 patients

N/ACompleted

NCT02377817 Design TherapeuticsPrenaBelt

Halifax PrenaBelt Trial

Start: Mar 2016Est. completion: Jan 201723 patients

N/ACompleted

NCT02379728 Design TherapeuticsPrenaBelt

Ghana PrenaBelt Trial: A Positional Therapy Device to Reduce Still-Birth

Start: Sep 2015Est. completion: Jun 2016200 patients

N/ACompleted

NCT02216318 Philipsblue light

Energy-efficient and Health Promoting Light for Elderly People

Start: Oct 2013Est. completion: Dec 201329 patients

N/ACompleted

NCT01508793 Temple TherapeuticsOptimize Sleep

Enhancing Sleep Duration: Effects on Children's Eating and Activity Behaviors

Start: Jan 2012Est. completion: Nov 2016103 patients

N/ACompleted

Phase Legend

Preclinical— Lab & animal studies

Phase 1— Safety & dosing

Phase 2— Efficacy testing

Phase 3— Large-scale trials

On Market— Approved & available

Key Insights

9 actively recruiting trials targeting 5,347 patients

24 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.