Postmenopause

Women's Health
4
Pipeline Programs
3
Companies
7
Clinical Trials
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
1
0
1
0
1
1
Early DiscoveryClinical DevelopmentMarket

Competitive Landscape

2 companies ranked by most advanced pipeline stage

Pfizer
PfizerNEW YORK, NY
4 programs
1
1
TrimegestonePhase 41 trial
Premarin/MPA 0.45 mg/1.5 mgPhase 11 trial
Conjugated Estrogen CreamN/A1 trial
PremarinN/A1 trial
Active Trials
NCT00484107Completed200Est. Oct 2006
NCT00380887Completed54
NCT00472927CompletedEst. Aug 2007
+1 more trials
Bayer
BayerLEVERKUSEN, Germany
3 programs
1
1
0.25mg DRSP / 0.5mg E2Phase 31 trial
Drospirenone/17ß-estradiolPhase 21 trial
E2/LNG oralN/A1 trial
Active Trials
NCT00913926Completed749Est. May 2009
NCT00420342Completed92Est. Sep 2008
NCT00522873Completed662Est. Aug 2009

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
PfizerTrimegestone
Bayer0.25mg DRSP / 0.5mg E2
BayerDrospirenone/17ß-estradiol
PfizerPremarin/MPA 0.45 mg/1.5 mg
BayerE2/LNG oral
PfizerConjugated Estrogen Cream
PfizerPremarin

Clinical Trials (7)

Total enrollment: 1,890 patients across 7 trials

NCT00195455PfizerTrimegestone

Study Evaluating Estradiol/Trimegestone in Vasomotor Symptoms (VMS) in Post-Menopausal Women.

Start: Feb 2005Est. completion: Mar 2007133 patients
Phase 4Completed
NCT00522873Bayer0.25mg DRSP / 0.5mg E2

Endometrial Safety Study

Start: Aug 2007Est. completion: Aug 2009662 patients
Phase 3Completed
NCT00420342BayerDrospirenone/17ß-estradiol

Effects of Angeliq and Prempro on Blood Pressure and Sodium Sensitivity in Postmenopausal Women With Prehypertension

Start: Jan 2007Est. completion: Sep 200892 patients
Phase 2Completed
NCT00472927PfizerPremarin/MPA 0.45 mg/1.5 mg

Bioequivalence Study of 3 New Formulations of Premarin/MPA Compared With Premarin/MPA (Prempro)

Start: May 2007Est. completion: Aug 2007
Phase 1Completed
NCT00913926BayerE2/LNG oral

Effects of Wellnara on Climacteric Symptoms

Start: Sep 2007Est. completion: May 2009749 patients
N/ACompleted
NCT00484107PfizerConjugated Estrogen Cream

Tolerability & Safety of Premarin Vaginal Cream in Indian Postmenopausal Women

Start: Sep 2005Est. completion: Oct 2006200 patients
N/ACompleted
NCT00380887PfizerPremarin

Study Comparing Four New Formulations for Premarin in Healthy Postmenopausal Women

Start: Jun 200554 patients
N/ACompleted

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Phase Legend

Preclinical— Lab & animal studies
Phase 1— Safety & dosing
Phase 2— Efficacy testing
Phase 3— Large-scale trials
On Market— Approved & available

Key Insights

1 late-stage (Phase 3) programs — potential near-term approvals
3 companies competing in this space

Related Indications

Endometriosis(43)Menopause(27)Polycystic Ovary Syndrome(14)Controlled Ovarian Stimulation(5)Vasomotor Symptoms Associated With Menopause(4)Polycystic Ovarian Syndrome(3)Preeclampsia(3)Uterine Fibroids(3)Uterine Leiomyomata (Fibroids)(3)Ovarian Hyperstimulation Syndrome(3)