PREMPRO

LOE Approaching

conjugated estrogens and medroxyprogesterone acetate

NDAORAL-28TABLET
Approved
Nov 1995
Lifecycle
LOE Approaching
Competitive Pressure
30/100
Clinical Trials
4

Mechanism of Action

Estrogen Receptor Agonists

Pharmacologic Class:

Estrogen

Clinical Trials (4)

NCT00543634Phase 1Completed

Study Comparing Premarin®/MPA, PREMPRO® and Provera® in Healthy Postmenopausal Women

Started Oct 2007
30 enrolled
Postmenopause
NCT00472927Phase 1Completed

Bioequivalence Study of 3 New Formulations of Premarin/MPA Compared With Premarin/MPA (Prempro)

Started May 2007
Postmenopause
NCT00420342Phase 2Completed

Effects of Angeliq and Prempro on Blood Pressure and Sodium Sensitivity in Postmenopausal Women With Prehypertension

Started Jan 2007
92 enrolled
PostmenopauseHypertensionPre-Hypertension
NCT00401219Phase 1Completed

Study Comparing Bioavailability of 3 New Formulations of Premarin/MPA With Premarin/MPA (PREMPRO) Reference Formulation

Started Nov 2006
Estrogen Replacement Therapy