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Infertility

29
Pipeline Programs
30
Companies
50
Clinical Trials
3 recruiting
0
Approved Products

Pipeline by Development Stage

Preclinical
Phase 1
Phase 1/2
Phase 2
Phase 2/3
Phase 3
On Market
0
4
0
2
1
8
14
Early DiscoveryClinical DevelopmentMarket

Drug Modality Breakdown

Vaccine
267%
Small Molecule
133%
+ 171 programs with unclassified modality

Competitive Landscape

32 companies ranked by most advanced pipeline stage

Human BioSciences
1
1
4
Influenza VaccinePhase 4Vaccine1 trial
Influenza VaccinePhase 4Vaccine1 trial
LetrozolePhase 4Small Molecule1 trial
rFSHPhase 41 trial
Elagolix 200 MGPhase 3
+12 more programs
Active Trials
NCT03799107Active Not Recruiting3,700Est. Jul 2025
NCT02246309Terminated31Est. Dec 2015
NCT00501800Active Not Recruiting1,250Est. Jul 2025
+11 more trials
MSD
MSDIreland - Ballydine
11 programs
2
5
Contraceptives, OralPhase 41 trial
CrinonePhase 41 trial
Double StimulationPhase 41 trial
HCGPhase 41 trial
corifollitropin alfaPhase 41 trial
+6 more programs
Active Trials
NCT01318291Completed166Est. Sep 2014
NCT04142190Completed1,351Est. Dec 2018
NCT02635607Unknown200Est. Mar 2017
+8 more trials
Sharp Therapeutics
2
5
Contraceptives, OralPhase 4
CrinonePhase 4
Double StimulationPhase 4
HCGPhase 4
corifollitropin alfaPhase 4
+6 more programs
Colorado Therapeutics
Colorado TherapeuticsCO - Louisville
9 programs
2
2
Elagolix 200 MGPhase 31 trial
Elagolix 200 MGPhase 31 trial
Elagolix 200 MGPhase 11 trial
Follicle Stimulating HormonePhase 11 trial
IVM mediaN/A1 trial
+4 more programs
Active Trials
NCT02516462Unknown100Est. Dec 2022
NCT00902382Completed264Est. Jun 2014
NCT01180387Completed1,640Est. Jan 2015
+6 more trials
Dong-A ST
Dong-A STKorea - Seoul
2 programs
1
1
DA-3801 InjectionPhase 31 trial
T-RPhase 11 trial
Active Trials
NCT01851512Completed27Est. Apr 2011
NCT01820728Completed93Est. Oct 2012
UNION therapeutics
1
LuverisPhase 21 trial
Active Trials
NCT01029470Unknown150Est. Mar 2011
Angeles Therapeutics
Angeles TherapeuticsCA - Los Angeles
1 program
1
Whole walnutsPhase 21 trial
Active Trials
NCT01505140Completed120Est. Dec 2010
AbbVie
AbbVieNORTH CHICAGO, IL
1 program
1
Elagolix 200 MGPhase 1
Ferring Pharmaceuticals
Ferring PharmaceuticalsArgentina - Buenos Aires
42 programs
AURORA-DonorN/A1 trial
Comprehensive Chromosome ScreeningN/A1 trial
Embryo cryopreservationN/A1 trial
Estradiol / ProgesteroneN/A
Fast Track to Fertility Algorithmic Text Messaging PlatformN/A1 trial
+37 more programs
Active Trials
NCT06280677Recruiting160Est. Sep 2026
NCT02032264Completed309Est. Jan 2017
NCT00963625Completed100Est. Oct 2010
+38 more trials
Merck & Co.
Merck & Co.RAHWAY, NJ
29 programs
AURORA-RecN/A1 trial
CCRI GroupN/A
Cetrorelix acetate and Follitropin alfaN/A1 trial
Control Ovarian Stimulation Timing TestN/A1 trial
Follitropin BetaN/A
+24 more programs
Active Trials
NCT04710264Completed137Est. Sep 2025
NCT01109654Completed2,175Est. Dec 2010
NCT02397135Unknown200Est. Sep 2016
+22 more trials
IBSA Institut Biochimique
IBSA Institut BiochimiqueSwitzerland - Lugano-Pazzallo
12 programs
Estradiol / ProgesteroneN/A1 trial
hFSH(Fostimon)N/A1 trial
Human hCG 10'000 IUPHASE_11 trial
Progesterone subcutaneousPHASE_21 trial
FSH-IBSAPHASE_31 trial
+7 more programs
Active Trials
NCT05232344Completed40Est. Feb 2024
NCT01107470Unknown2,000Est. Apr 2013
NCT03735030Completed26Est. Aug 2019
+9 more trials
Progyny
ProgynyNY - New York
9 programs
Correlating Time-Lapse Parameters With aCGH Testing in IVF Treatment (aCGH Study)N/A1 trial
Eeva System StudyN/A1 trial
Eeva™ Continued Access Study: Assessing the Usability of Eeva in a Clinical SettingN/A1 trial
Eeva™ Pregnancy Investigational Clinical Study: A Postmarket Follow-Up StudyN/A1 trial
Eeva™ TestN/A1 trial
+4 more programs
Active Trials
NCT02141685Unknown50Est. Feb 2016
NCT01369446Completed160Est. Apr 2012
NCT01617993Completed31Est. Feb 2013
+6 more trials
Conceivable Life Sciences
AURA assisted ART treatmentN/A1 trial
Automated VitrificationN/A1 trial
Gamete preparation, ICSI, embryo culture and vitrification robot assistantN/A1 trial
Active Trials
NCT06581068Recruiting150Est. Feb 2027
NCT07197983Recruiting125Est. Jun 2026
NCT06074835Completed42Est. Oct 2025
Labcorp
LabcorpBURLINGTON, NC
3 programs
HyperSpermN/A1 trial
Standard Sperm PreparationN/A1 trial
PGDPHASE_21 trial
Active Trials
NCT05680363Completed41Est. Dec 2025
NCT07478549Not Yet Recruiting202Est. Aug 2027
NCT02000349Unknown186Est. Dec 2016
CooperSurgical
CooperSurgicalCT - Trumbull
2 programs
Benchtop IncubatorN/A1 trial
Non-Euploid Embryo Transfer (NEET) RegistryN/A1 trial
Active Trials
NCT06214936Recruiting252Est. Jun 2026
NCT07036536Recruiting1,000Est. Dec 2030
Conception
ConceptionCA - Berkeley
2 programs
Lifestyle behaviour and dietary habits assessmentN/A1 trial
PIPELLE ENDOMETRIAL SAMPLINGN/A1 trial
Active Trials
NCT03050944Completed250Est. Dec 2016
NCT00796341Completed99Est. Sep 2008
Genomic Prediction
Genomic PredictionNJ - Hackettstown
2 programs
M2 TestN/A1 trial
Preimplantation Genetic TestingN/A1 trial
Active Trials
NCT04544462Active Not Recruiting500Est. Dec 2026
NCT04528498Recruiting500Est. Dec 2025
Overture Life
2 programs
Overture Metabolomics Embryo SelectionN/A1 trial
Overture Metabolomics Embryo SelectionN/A1 trial
Active Trials
NCT04878991Unknown410Est. Jan 2024
NCT04976920Unknown205Est. Jan 2024
Teva
TevaIsrael - Petach Tikva
2 programs
DR-2011PHASE_21 trial
DR-2011PHASE_31 trial
Active Trials
NCT00117468Completed20Est. Apr 2006
NCT00615251Completed1,297Est. Aug 2009
Martin Pharmaceuticals
1 program
Clinical Tests to Predict the Success of Assisted Reproductive TechniquesN/A1 trial
Active Trials
NCT02437578Completed542Est. Mar 2019
Abbott
AbbottABBOTT PARK, IL
1 program
Duphaston®N/A2 trials
Active Trials
NCT04249297Unknown1,150Est. Dec 2022
NCT03690765Completed350Est. May 2020
Femasys
FemasysSUWANEE, GA
1 program
FemaSeed Localized Directional InseminationN/A1 trial
Active Trials
NCT04968847Completed314Est. Apr 2024
Alife
AlifeGEORGE TOWN, Cayman Islands
1 program
Hera SystemN/A1 trial
Active Trials
NCT05483985Unknown440Est. Jan 2025
Innovation Pharmaceuticals
1 program
Hyalobarrier® gel endoN/A1 trial
Active Trials
NCT03880435Active Not Recruiting419Est. May 2025
Nordic Pharma
Nordic PharmaFrance - Paris
1 program
Hyalobarrier® gel endoN/A
Genomics
GenomicsUK - Oxford
1 program
Non-invasive chromosome screening(NICS)N/A1 trial
Active Trials
NCT04339166Completed1,152Est. Aug 2024
Genesis Therapeutics
Genesis TherapeuticsCA - Burlingame
1 program
Preimplantation Genetic Screening by NGSN/A
Illumina
IlluminaCA - Hayward
1 program
Preimplantation Genetic Screening by NGSN/A1 trial
Active Trials
NCT02268786Completed661Est. Dec 2016
City Therapeutics
City TherapeuticsMA - Cambridge
1 program
measuring cell freeDNAN/A1 trial
Active Trials
NCT02480491CompletedEst. May 2015
Qilu Pharmaceutical
Qilu PharmaceuticalChina - Jinan
1 program
QL1012PHASE_31 trial
Active Trials
NCT05149924Completed354Est. Oct 2019

+2 more companies

Trial Timeline

Clinical trial activity over time

2021
2022
2023
2024
2025
2026
2027
2028
2029
Merck & Co.rhFSH+rhLH
MSDDouble Stimulation
MSDCrinone
GuerbetLipiodol UF
Merck & Co.GERI+ incubator
Merck & Co.Forielle
Human BioSciencesInfluenza Vaccine
Human BioSciencesInfluenza Vaccine
Ferring Pharmaceuticalsmenotropin
MSDcorifollitropin alfa
Ferring PharmaceuticalsEndometrin® plus Progesterone in Oil
IBSA Institut BiochimiqueUrofollitrophin
Human BioSciencesrFSH
MSDHCG
MSDContraceptives, Oral

Showing 15 of 50 trials with date data

Clinical Trials (50)

Total enrollment: 15,792 patients across 50 trials

PErsonalized Addition of Recombinant LH in Ovarian Stimulation

Start: Feb 2021Est. completion: Nov 2027120 patients
Phase 4Recruiting
NCT04446845MSDDouble Stimulation

Double Stimulation Followed by a Fresh Embryo Transfer

Start: Oct 2020Est. completion: May 2023120 patients
Phase 4Completed

Efficacy and Safety of Crinone Versus Combination Medication (ACCESS)

Start: May 2019Est. completion: Oct 2021172 patients
Phase 4Terminated

Sonographic Hysterosalpingography: Oil vs Water Based Media (SHOW Trial)

Start: Jan 2019Est. completion: Aug 202158 patients
Phase 4Completed
NCT03164551Merck & Co.GERI+ incubator

TICON-Day 3, Time Lapse Versus Conventional Method in Day 3 Embryo Culture and Assessment

Start: Apr 2018Est. completion: Nov 2019408 patients
Phase 4Terminated

Clinical Performance and Safety Investigation of ENDOmetrial Washing MEdical DEvice Forielle

Start: Jan 2018Est. completion: Jun 20189 patients
Phase 4Terminated

Effect of Influenza Vaccination on IVF Outcomes - IVF

Start: Jan 2017Est. completion: Dec 2024238 patients
Phase 4Unknown

Effect of Influenza Vaccination on Donor Egg Recipient Outcomes

Start: Jan 2017Est. completion: Dec 2021126 patients
Phase 4Unknown

MENOPUR® in a Gonadotropin-Releasing Hormone (GnRH) Antagonist Cycle With Single-Blastocyst Transfer in a High Responder Subject Population

Start: Aug 2015Est. completion: Feb 2017620 patients
Phase 4Completed
NCT02466204MSDcorifollitropin alfa

Efficacy of Corifollitropin Alfa Versus Follitropin Beta in Aged IVF (In-vitro Fertilization) Patients

Start: Jun 2015Est. completion: Aug 2017400 patients
Phase 4Completed
NCT02254577Ferring PharmaceuticalsEndometrin® plus Progesterone in Oil

Vaginal Compared to Intramuscular Progesterone for Frozen Embryo Transfer

Start: Oct 2014Est. completion: Apr 20181,139 patients
Phase 4Completed

FSH in GnRH-AntagoniST Controlled Ovarian Hyperstimulation Cycles (FAST)

Start: Jan 2014Est. completion: Aug 2017710 patients
Phase 4Completed

Randomized Controlled Trial Comparing Embryonic Quality in rFSH Versus hMG in IVF Protocol With GnRH Antagonist

Start: Jan 2014Est. completion: Dec 2014188 patients
Phase 4Completed

Study of Dual Trigger Ovulation in Oocyte Donors

Start: Jan 2013Est. completion: Jun 201626 patients
Phase 4Terminated
NCT01638767MSDContraceptives, Oral

NuvaRing Versus Marvelon in the Coordination of In Vitro Fertilization Cycles

Start: Jul 2012Est. completion: Jul 20147 patients
Phase 4Terminated

Anti-Mullerian Hormone (AMH) Versus Antral Follicle Count (AFC) Guided rFSH Dosing Study

Start: Oct 2011Est. completion: Dec 2012348 patients
Phase 4Completed

Menopur Mixed Protocol

Start: Jul 2011Est. completion: Jan 2012122 patients
Phase 4Completed

Progesterone Serum Levels in Subfertile Female Patients Undergoing in Vitro Fertilisation (IVF)

Start: Oct 2010Est. completion: Jun 2013124 patients
Phase 4Completed

Vaginal Progesterone Versus Progesterone in Oil in Donor Egg Recipient In Vitro Fertilization Cycles Utilizing Vitrified Donor Eggs

Start: Feb 2010Est. completion: Sep 201110 patients
Phase 4Completed

MENOPUR® Versus FOLLISTIM®

Start: Dec 2008Est. completion: Jan 2010173 patients
Phase 4Completed

Does Letrozole Improve the Outcomes and/or Reduce the Cost of IVF-ET Cycles?

Start: Sep 2008Est. completion: Apr 20100
Phase 4Withdrawn
NCT00829244Merck & Co.GONAL f® prefilled pen

CONSORT Randomized Controlled Trial in Assisted Reproductive Technology

Start: Aug 2008Est. completion: Jan 2010200 patients
Phase 4Completed

Individual Versus Standard Follicle Stimulating Hormone Dose for Controlled Ovarian Stimulation and Insemination

Start: Sep 2006Est. completion: Oct 2008
Phase 4Completed

A Study of the Efficacy and Safety of Highly Purified Menotrophin Versus Recombinant Follitropin Alfa

Start: Oct 2005Est. completion: Apr 200980 patients
Phase 4Completed
NCT00953628Merck & Co.10000 IU urinary HCG

Endometrial Advancement After Rec or u-HCG Triggering

Start: Aug 2005Est. completion: Dec 2008130 patients
Phase 4Completed
NCT07340827Merck & Co.Follitropin alfa/lutropin alfa

A Study to Compare the Efficacy and Safety of Follitropin Alfa/Lutropin Alfa Versus hMG in Japanese Participants With LH and FSH Deficiency Undergoing ART (HINATA)

Start: Feb 2026Est. completion: Jun 2029333 patients
Phase 3Recruiting

Pre-IVF Treatment With a GnRH Antagonist in Women With endometriosis_temp

Start: Mar 2024Est. completion: Sep 2026297 patients
Phase 3Recruiting
NCT04549116IBSA Institut BiochimiqueProgesterone-IBSA Injectable Solution

Subcutaneous Progesterone in Frozen- Thawed Single Euploid Blastocyst Transfer.

Start: Oct 2022Est. completion: Jun 2026680 patients
Phase 3Active Not Recruiting

A Trial to Compare the Ovarian Response of REKOVELLE and GONAL-F in Conventional Dosing in Women Undergoing Controlled Ovarian Stimulation

Start: Jul 2022Est. completion: Apr 2024302 patients
Phase 3Completed

Pre-IVF Treatment With a GnRH Antagonist in Women With Endometriosis

Start: Mar 2022Est. completion: May 2025103 patients
Phase 3Completed

Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Indian Women

Start: Dec 2021Est. completion: Dec 2023220 patients
Phase 3Completed
NCT03895099MSDDesogestrel early follicular phase

New Ovarian Stimulation With Random Start, Use of Progestin Protocol for Oocyte Donors

Start: Sep 2020Est. completion: Oct 2023110 patients
Phase 3Completed
NCT04163458Ferring PharmaceuticalsMENOPUR solution for injection in pre-filled pen, 1200 IU/1.92 mL

Comparison of MENOPUR Liquid and Powder in Women Undergoing Assisted Reproductive Technology (ART)

Start: Oct 2019Est. completion: Jul 2021405 patients
Phase 3Completed

Efficacy and Safety of QL1012 in Women for Assisted Reproductive Treatment

Start: Oct 2018Est. completion: Oct 2019354 patients
Phase 3Completed

Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-1)

Start: Oct 2018Est. completion: Nov 2020579 patients
Phase 3Completed

Efficacy and Safety of FE 999049 in Controlled Ovarian Stimulation in Japanese Women

Start: Jul 2017Est. completion: Jul 2019373 patients
Phase 3Completed

Interest of Estrogen Scheduling Before Ovarian Stimulation With Corifollitropin Alfa

Start: Nov 2016Est. completion: Jan 2023334 patients
Phase 3Completed
NCT02449889Ferring Pharmaceuticalshighly purified human chorionic gonadotropin

A Randomised Trial Using Highly Purified Human Chorionic Gonadotropin (HP-hCG) and Recombinant Human Chorionic Gonadotropin (rhCG) in Women Undergoing Controlled Ovarian Stimulation

Start: Apr 2016Est. completion: Mar 2018176 patients
Phase 3Completed
NCT02310919Ferring PharmaceuticalsLow dose hCG plus FSH co-trigger

Administration of Follicle-stimulating Hormone (FSH) and Low Dose Human Chorionic Gonadotropin (hCG) for Oocyte Maturity While Decreasing hCG Exposure in In Vitro Fertilization (IVF) Cycles

Start: Sep 2014Est. completion: Jun 2018105 patients
Phase 3Completed

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 2

Start: Mar 2014Est. completion: Jan 2017513 patients
Phase 3Completed

Phase 3 Study to Evaluate the Efficacy and Safety of Pergoveris® in Assisted Reproductive Technology (ESPART)

Start: Jan 2014Est. completion: Aug 2015939 patients
Phase 3Completed
NCT01922193Ferring PharmaceuticalsHighly Purified Urofollitropin

Evaluation of Efficacy and Safety of Highly Purified Urofollitropin in Chinese Females Undergoing an Assisted Reproductive Technology (ART) Program

Start: Oct 2013Est. completion: Apr 2015263 patients
Phase 3Completed

Evidence-based Stimulation Trial With Human rFSH in Europe and Rest of World 1

Start: Oct 2013Est. completion: Jan 20171,329 patients
Phase 3Completed

Safety and Efficacy Study in in Vitro Fertilisation (IVF) Patients

Start: Feb 2011Est. completion: Dec 2013270 patients
Phase 3Completed
NCT00884221Ferring PharmaceuticalsHighly purified menotrophin

MENOPUR in Gonadotrophin-releasing Hormone (GnRH) Antagonist Cycles With Single Embryo Transfer

Start: Jul 2009Est. completion: Jan 2011749 patients
Phase 3Completed

A Clinical Trial to Evaluate the Efficacy and Safety of DR-2011 for In Vitro Fertilization

Start: Feb 2008Est. completion: Aug 20091,297 patients
Phase 3Completed
NCT01820728Dong-A STDA-3801 Injection

A Phase III Clinical Study to Compare the Efficacy and Safety of DA-3801 and That of Gonal-F®

Start: Jan 2007Est. completion: Oct 201293 patients
Phase 3Completed

Clinical Tolerance and Equivalence of hCG-IBSA vs Recombinant Human Chorionic Gonadotrophin in Women Undergoing In Vitro Fertilisation

Start: Aug 2005Est. completion: Dec 2008144 patients
Phase 3Completed

Clinical Study of Clinical Efficacy and Tolerability of hMG-IBSA s.c.in Women Undergoing COH in an ART Programme (IVF).

Start: May 2005Est. completion: Mar 2009144 patients
Phase 3Completed

Clinical Efficacy and Tolerability of Two FSH Preparations (Human FSH Versus rFSH - Follitropin Alpha) in Women Undergoing IVF

Start: Mar 2005Est. completion: May 2006152 patients
Phase 3Completed

Related Jobs

Phase Legend

PreclinicalLab & animal studies
Phase 1Safety & dosing
Phase 2Efficacy testing
Phase 3Large-scale trials
On MarketApproved & available

Key Insights

8 late-stage (Phase 3) programs, potential near-term approvals
3 actively recruiting trials targeting 15,792 patients
30 companies competing in this space

The information on this page is for informational purposes only and should not be used as a substitute for professional medical advice. Drug information is sourced from FDA, DailyMed, and other government databases. Adverse event data from FAERS does not establish causation. Always consult a healthcare professional for medical decisions.